| Full name: nucleoporin 188 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 9q34.11 | ||
| Entrez ID: 23511 | HGNC ID: HGNC:17859 | Ensembl Gene: ENSG00000095319 | OMIM ID: 615587 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of NUP188:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NUP188 | 23511 | 212691_at | 0.2179 | 0.5204 | |
| GSE20347 | NUP188 | 23511 | 212691_at | -0.0519 | 0.6461 | |
| GSE23400 | NUP188 | 23511 | 212691_at | 0.0484 | 0.3770 | |
| GSE26886 | NUP188 | 23511 | 212691_at | 0.0906 | 0.6043 | |
| GSE29001 | NUP188 | 23511 | 212691_at | -0.1224 | 0.4643 | |
| GSE38129 | NUP188 | 23511 | 212691_at | 0.1457 | 0.1669 | |
| GSE45670 | NUP188 | 23511 | 212691_at | 0.1373 | 0.1920 | |
| GSE53622 | NUP188 | 23511 | 49963 | -0.0460 | 0.5892 | |
| GSE53624 | NUP188 | 23511 | 49963 | 0.2486 | 0.0001 | |
| GSE63941 | NUP188 | 23511 | 212691_at | 0.6022 | 0.0671 | |
| GSE77861 | NUP188 | 23511 | 212691_at | 0.0733 | 0.6409 | |
| GSE97050 | NUP188 | 23511 | A_24_P237753 | -0.2342 | 0.6209 | |
| SRP007169 | NUP188 | 23511 | RNAseq | 0.6461 | 0.0654 | |
| SRP008496 | NUP188 | 23511 | RNAseq | 0.4383 | 0.0675 | |
| SRP064894 | NUP188 | 23511 | RNAseq | 0.0287 | 0.8835 | |
| SRP133303 | NUP188 | 23511 | RNAseq | 0.2923 | 0.1036 | |
| SRP159526 | NUP188 | 23511 | RNAseq | 0.3252 | 0.2007 | |
| SRP193095 | NUP188 | 23511 | RNAseq | 0.2166 | 0.0771 | |
| SRP219564 | NUP188 | 23511 | RNAseq | -0.1517 | 0.4862 | |
| TCGA | NUP188 | 23511 | RNAseq | 0.1732 | 0.0006 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NUP188 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NUP188:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NUP188 | 23511 | 6 | 9 | 15 | |
| GSE20123 | NUP188 | 23511 | 6 | 9 | 15 | |
| GSE43470 | NUP188 | 23511 | 5 | 8 | 30 | |
| GSE46452 | NUP188 | 23511 | 6 | 13 | 40 | |
| GSE47630 | NUP188 | 23511 | 3 | 16 | 21 | |
| GSE54993 | NUP188 | 23511 | 3 | 3 | 64 | |
| GSE54994 | NUP188 | 23511 | 11 | 8 | 34 | |
| GSE60625 | NUP188 | 23511 | 0 | 0 | 11 | |
| GSE74703 | NUP188 | 23511 | 5 | 6 | 25 | |
| GSE74704 | NUP188 | 23511 | 3 | 7 | 10 | |
| TCGA | NUP188 | 23511 | 27 | 24 | 45 |
Total number of gains: 75; Total number of losses: 103; Total Number of normals: 310.
Somatic mutations of NUP188:
Generating mutation plots.
Highly correlated genes for NUP188:
Showing top 20/329 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NUP188 | CDC42EP1 | 0.752561 | 3 | 0 | 3 |
| NUP188 | PI4K2A | 0.741607 | 3 | 0 | 3 |
| NUP188 | NOLC1 | 0.740864 | 3 | 0 | 3 |
| NUP188 | ZNHIT1 | 0.721256 | 3 | 0 | 3 |
| NUP188 | MPI | 0.70939 | 3 | 0 | 3 |
| NUP188 | BCAR3 | 0.709318 | 3 | 0 | 3 |
| NUP188 | TMEM69 | 0.696678 | 3 | 0 | 3 |
| NUP188 | SLC25A39 | 0.695893 | 4 | 0 | 4 |
| NUP188 | SURF6 | 0.692734 | 5 | 0 | 5 |
| NUP188 | MRPL42 | 0.691949 | 4 | 0 | 3 |
| NUP188 | MRPL3 | 0.684766 | 4 | 0 | 4 |
| NUP188 | ZNF484 | 0.676119 | 4 | 0 | 3 |
| NUP188 | BIN3 | 0.672854 | 3 | 0 | 3 |
| NUP188 | SF3B3 | 0.671389 | 4 | 0 | 3 |
| NUP188 | BPHL | 0.670729 | 3 | 0 | 3 |
| NUP188 | RABIF | 0.670229 | 4 | 0 | 4 |
| NUP188 | GPBP1L1 | 0.66939 | 3 | 0 | 3 |
| NUP188 | CAPZA1 | 0.66782 | 4 | 0 | 3 |
| NUP188 | PRPS2 | 0.664467 | 3 | 0 | 3 |
| NUP188 | NOL11 | 0.664372 | 4 | 0 | 3 |
For details and further investigation, click here
