MRPL51

 

Full name: mitochondrial ribosomal protein L51 Alias Symbol: CDA09|HSPC241|bMRP64
Type: protein-coding gene Cytoband: 12p13.31
Entrez ID: 51258 HGNC ID: HGNC:14044 Ensembl Gene: ENSG00000111639 OMIM ID: 611855
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of MRPL51:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 MRPL51 51258 223086_x_at 0.1983 0.3929
GSE26886 MRPL51 51258 223086_x_at 0.2263 0.2249
GSE45670 MRPL51 51258 223086_x_at 0.3036 0.0249
GSE53622 MRPL51 51258 57957 0.5594 0.0000
GSE53624 MRPL51 51258 57957 0.6968 0.0000
GSE63941 MRPL51 51258 223086_x_at 0.2076 0.5667
GSE77861 MRPL51 51258 223086_x_at 0.1550 0.5910
GSE97050 MRPL51 51258 A_23_P99138 0.3011 0.3197
SRP007169 MRPL51 51258 RNAseq -0.0197 0.9599
SRP008496 MRPL51 51258 RNAseq -0.0310 0.9045
SRP064894 MRPL51 51258 RNAseq 0.3593 0.2629
SRP133303 MRPL51 51258 RNAseq 0.5408 0.0091
SRP159526 MRPL51 51258 RNAseq 0.1934 0.3693
SRP193095 MRPL51 51258 RNAseq -0.2814 0.0930
SRP219564 MRPL51 51258 RNAseq 0.0470 0.8404
TCGA MRPL51 51258 RNAseq 0.2307 0.0000

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by MRPL51 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of MRPL51:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 MRPL51 51258 9 4 17
GSE20123 MRPL51 51258 9 4 17
GSE43470 MRPL51 51258 8 3 32
GSE46452 MRPL51 51258 10 1 48
GSE47630 MRPL51 51258 12 2 26
GSE54993 MRPL51 51258 1 10 59
GSE54994 MRPL51 51258 10 2 41
GSE60625 MRPL51 51258 0 1 10
GSE74703 MRPL51 51258 7 2 27
GSE74704 MRPL51 51258 5 3 12
TCGA MRPL51 51258 40 6 50

Total number of gains: 111; Total number of losses: 38; Total Number of normals: 339.  

 

Somatic mutations of MRPL51:

 

Generating mutation plots.

 

Highly correlated genes for MRPL51:

 

Showing top 20/1257 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
MRPL51PARG0.784447303
MRPL51NADSYN10.779755303
MRPL51TUFM0.776983303
MRPL51GCDH0.761171303
MRPL51TMED20.760659303
MRPL51EMG10.74597707
MRPL51ALDH5A10.745857303
MRPL51TAF100.741346303
MRPL51STX100.73998303
MRPL51CDC42EP10.737499303
MRPL51PDCD60.737189303
MRPL51SRSF100.732843404
MRPL51DOCK60.730521303
MRPL51PHB20.72291907
MRPL51WIPI10.721888303
MRPL51PDIA40.721751505
MRPL51RUNDC10.721659303
MRPL51PRELID10.721646303
MRPL51MTCH20.718874303
MRPL51NDUFA90.718627909

For details and further investigation, click here