| Full name: FKBP prolyl isomerase 4 | Alias Symbol: FKBP59|FKBP52 | ||
| Type: protein-coding gene | Cytoband: 12p13.33 | ||
| Entrez ID: 2288 | HGNC ID: HGNC:3720 | Ensembl Gene: ENSG00000004478 | OMIM ID: 600611 |
| Drug and gene relationship at DGIdb | |||
Expression of FKBP4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FKBP4 | 2288 | 200895_s_at | 0.2928 | 0.4562 | |
| GSE20347 | FKBP4 | 2288 | 200895_s_at | 0.1840 | 0.3238 | |
| GSE23400 | FKBP4 | 2288 | 200895_s_at | 0.1911 | 0.0091 | |
| GSE26886 | FKBP4 | 2288 | 200895_s_at | -0.0482 | 0.8352 | |
| GSE29001 | FKBP4 | 2288 | 200895_s_at | 0.2215 | 0.3485 | |
| GSE38129 | FKBP4 | 2288 | 200895_s_at | 0.2907 | 0.0552 | |
| GSE45670 | FKBP4 | 2288 | 200895_s_at | 0.4639 | 0.0594 | |
| GSE53622 | FKBP4 | 2288 | 64378 | 0.4766 | 0.0000 | |
| GSE53624 | FKBP4 | 2288 | 64378 | 0.4930 | 0.0000 | |
| GSE63941 | FKBP4 | 2288 | 200895_s_at | 1.8266 | 0.0018 | |
| GSE77861 | FKBP4 | 2288 | 200895_s_at | 0.3096 | 0.1349 | |
| GSE97050 | FKBP4 | 2288 | A_32_P71788 | 0.1338 | 0.6430 | |
| SRP007169 | FKBP4 | 2288 | RNAseq | -0.6502 | 0.2656 | |
| SRP008496 | FKBP4 | 2288 | RNAseq | -0.5142 | 0.1594 | |
| SRP064894 | FKBP4 | 2288 | RNAseq | -0.0196 | 0.9374 | |
| SRP133303 | FKBP4 | 2288 | RNAseq | 0.4623 | 0.0940 | |
| SRP159526 | FKBP4 | 2288 | RNAseq | 0.4327 | 0.0607 | |
| SRP193095 | FKBP4 | 2288 | RNAseq | 0.1556 | 0.3194 | |
| SRP219564 | FKBP4 | 2288 | RNAseq | -0.0322 | 0.9242 | |
| TCGA | FKBP4 | 2288 | RNAseq | 0.1018 | 0.0740 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by FKBP4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FKBP4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FKBP4 | 2288 | 6 | 4 | 20 | |
| GSE20123 | FKBP4 | 2288 | 6 | 4 | 20 | |
| GSE43470 | FKBP4 | 2288 | 11 | 4 | 28 | |
| GSE46452 | FKBP4 | 2288 | 10 | 1 | 48 | |
| GSE47630 | FKBP4 | 2288 | 12 | 2 | 26 | |
| GSE54993 | FKBP4 | 2288 | 1 | 10 | 59 | |
| GSE54994 | FKBP4 | 2288 | 9 | 2 | 42 | |
| GSE60625 | FKBP4 | 2288 | 0 | 1 | 10 | |
| GSE74703 | FKBP4 | 2288 | 11 | 2 | 23 | |
| GSE74704 | FKBP4 | 2288 | 4 | 2 | 14 | |
| TCGA | FKBP4 | 2288 | 40 | 6 | 50 |
Total number of gains: 110; Total number of losses: 38; Total Number of normals: 340.
Somatic mutations of FKBP4:
Generating mutation plots.
Highly correlated genes for FKBP4:
Showing top 20/651 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FKBP4 | SCAF1 | 0.795764 | 3 | 0 | 3 |
| FKBP4 | CDC42EP1 | 0.783524 | 3 | 0 | 3 |
| FKBP4 | SELPLG | 0.762194 | 3 | 0 | 3 |
| FKBP4 | ZSCAN21 | 0.735985 | 3 | 0 | 3 |
| FKBP4 | RPS19BP1 | 0.735382 | 3 | 0 | 3 |
| FKBP4 | ZBED1 | 0.727787 | 3 | 0 | 3 |
| FKBP4 | TRAPPC1 | 0.723372 | 3 | 0 | 3 |
| FKBP4 | FLOT2 | 0.711192 | 4 | 0 | 3 |
| FKBP4 | NUCKS1 | 0.710974 | 3 | 0 | 3 |
| FKBP4 | MAP2K7 | 0.710435 | 3 | 0 | 3 |
| FKBP4 | PRELID1 | 0.708067 | 4 | 0 | 4 |
| FKBP4 | MLF2 | 0.707076 | 12 | 0 | 12 |
| FKBP4 | RPS6KA4 | 0.69696 | 3 | 0 | 3 |
| FKBP4 | ANKRD54 | 0.69541 | 3 | 0 | 3 |
| FKBP4 | EPB41L5 | 0.692197 | 3 | 0 | 3 |
| FKBP4 | TMSB15B | 0.684693 | 3 | 0 | 3 |
| FKBP4 | PTCD1 | 0.678891 | 3 | 0 | 3 |
| FKBP4 | DYNC1H1 | 0.676668 | 3 | 0 | 3 |
| FKBP4 | TMEM63B | 0.676528 | 3 | 0 | 3 |
| FKBP4 | RAB11B | 0.670806 | 4 | 0 | 3 |
For details and further investigation, click here
