| Full name: acetyl-CoA acyltransferase 2 | Alias Symbol: DSAEC | ||
| Type: protein-coding gene | Cytoband: 18q21.1 | ||
| Entrez ID: 10449 | HGNC ID: HGNC:83 | Ensembl Gene: ENSG00000167315 | OMIM ID: 604770 |
| Drug and gene relationship at DGIdb | |||
Expression of ACAA2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ACAA2 | 10449 | 202003_s_at | -0.7470 | 0.3827 | |
| GSE20347 | ACAA2 | 10449 | 202003_s_at | -0.6273 | 0.0689 | |
| GSE23400 | ACAA2 | 10449 | 202003_s_at | -0.5146 | 0.0000 | |
| GSE26886 | ACAA2 | 10449 | 202003_s_at | -1.5012 | 0.0000 | |
| GSE29001 | ACAA2 | 10449 | 202003_s_at | -0.8086 | 0.0155 | |
| GSE38129 | ACAA2 | 10449 | 202003_s_at | -0.6712 | 0.0239 | |
| GSE45670 | ACAA2 | 10449 | 202003_s_at | -1.4014 | 0.0001 | |
| GSE53622 | ACAA2 | 10449 | 46964 | -0.8248 | 0.0000 | |
| GSE53624 | ACAA2 | 10449 | 46964 | -0.6873 | 0.0000 | |
| GSE63941 | ACAA2 | 10449 | 202003_s_at | -2.9208 | 0.0286 | |
| GSE77861 | ACAA2 | 10449 | 202003_s_at | -0.8020 | 0.1134 | |
| GSE97050 | ACAA2 | 10449 | A_23_P89799 | -0.4703 | 0.3128 | |
| SRP007169 | ACAA2 | 10449 | RNAseq | 0.0508 | 0.9391 | |
| SRP008496 | ACAA2 | 10449 | RNAseq | 0.2555 | 0.5714 | |
| SRP064894 | ACAA2 | 10449 | RNAseq | -0.2754 | 0.2813 | |
| SRP133303 | ACAA2 | 10449 | RNAseq | -0.3880 | 0.1744 | |
| SRP159526 | ACAA2 | 10449 | RNAseq | -0.1810 | 0.6553 | |
| SRP193095 | ACAA2 | 10449 | RNAseq | -0.4250 | 0.2402 | |
| SRP219564 | ACAA2 | 10449 | RNAseq | -0.8478 | 0.1117 | |
| TCGA | ACAA2 | 10449 | RNAseq | -0.5107 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by ACAA2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ACAA2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ACAA2 | 10449 | 0 | 9 | 21 | |
| GSE20123 | ACAA2 | 10449 | 0 | 9 | 21 | |
| GSE43470 | ACAA2 | 10449 | 0 | 4 | 39 | |
| GSE46452 | ACAA2 | 10449 | 1 | 26 | 32 | |
| GSE47630 | ACAA2 | 10449 | 5 | 20 | 15 | |
| GSE54993 | ACAA2 | 10449 | 9 | 0 | 61 | |
| GSE54994 | ACAA2 | 10449 | 1 | 17 | 35 | |
| GSE60625 | ACAA2 | 10449 | 0 | 4 | 7 | |
| GSE74703 | ACAA2 | 10449 | 0 | 4 | 32 | |
| GSE74704 | ACAA2 | 10449 | 0 | 6 | 14 | |
| TCGA | ACAA2 | 10449 | 10 | 43 | 43 |
Total number of gains: 26; Total number of losses: 142; Total Number of normals: 320.
Somatic mutations of ACAA2:
Generating mutation plots.
Highly correlated genes for ACAA2:
Showing top 20/969 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ACAA2 | ZFP36L1 | 0.724992 | 3 | 0 | 3 |
| ACAA2 | NKTR | 0.719332 | 3 | 0 | 3 |
| ACAA2 | CDS2 | 0.715704 | 3 | 0 | 3 |
| ACAA2 | RASGEF1B | 0.711939 | 3 | 0 | 3 |
| ACAA2 | FAM98A | 0.707545 | 3 | 0 | 3 |
| ACAA2 | NPRL2 | 0.702989 | 3 | 0 | 3 |
| ACAA2 | FNIP2 | 0.698092 | 4 | 0 | 3 |
| ACAA2 | TNFSF12 | 0.696738 | 3 | 0 | 3 |
| ACAA2 | PRPF38A | 0.695631 | 3 | 0 | 3 |
| ACAA2 | TRIM6 | 0.691072 | 3 | 0 | 3 |
| ACAA2 | ZNF23 | 0.686754 | 3 | 0 | 3 |
| ACAA2 | RASSF3 | 0.686331 | 4 | 0 | 4 |
| ACAA2 | RHBDF1 | 0.685345 | 4 | 0 | 4 |
| ACAA2 | LIN7A | 0.6837 | 4 | 0 | 3 |
| ACAA2 | DNAJC21 | 0.682904 | 3 | 0 | 3 |
| ACAA2 | FEM1B | 0.679762 | 3 | 0 | 3 |
| ACAA2 | PLEKHB1 | 0.675863 | 5 | 0 | 5 |
| ACAA2 | KRT78 | 0.673505 | 3 | 0 | 3 |
| ACAA2 | PBX2 | 0.673357 | 4 | 0 | 3 |
| ACAA2 | AGL | 0.672983 | 3 | 0 | 3 |
For details and further investigation, click here
