| Full name: RAB6B, member RAS oncogene family | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 3q22.1 | ||
| Entrez ID: 51560 | HGNC ID: HGNC:14902 | Ensembl Gene: ENSG00000154917 | OMIM ID: 615852 |
| Drug and gene relationship at DGIdb | |||
Expression of RAB6B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RAB6B | 51560 | 221792_at | -0.2214 | 0.7318 | |
| GSE20347 | RAB6B | 51560 | 221792_at | 0.2818 | 0.0488 | |
| GSE23400 | RAB6B | 51560 | 221792_at | -0.0825 | 0.2237 | |
| GSE26886 | RAB6B | 51560 | 221792_at | 0.7852 | 0.0518 | |
| GSE29001 | RAB6B | 51560 | 221792_at | 0.0738 | 0.7625 | |
| GSE38129 | RAB6B | 51560 | 221792_at | -0.1270 | 0.4992 | |
| GSE45670 | RAB6B | 51560 | 225259_at | 0.0960 | 0.8250 | |
| GSE53622 | RAB6B | 51560 | 4870 | -0.5035 | 0.0323 | |
| GSE53624 | RAB6B | 51560 | 4870 | -0.1120 | 0.5801 | |
| GSE63941 | RAB6B | 51560 | 221792_at | 0.8273 | 0.1244 | |
| GSE77861 | RAB6B | 51560 | 221792_at | 0.2457 | 0.1695 | |
| GSE97050 | RAB6B | 51560 | A_24_P475349 | -0.6790 | 0.1820 | |
| SRP007169 | RAB6B | 51560 | RNAseq | 1.6123 | 0.0064 | |
| SRP008496 | RAB6B | 51560 | RNAseq | 1.9722 | 0.0000 | |
| SRP064894 | RAB6B | 51560 | RNAseq | 0.3261 | 0.3639 | |
| SRP133303 | RAB6B | 51560 | RNAseq | 0.5178 | 0.1556 | |
| SRP159526 | RAB6B | 51560 | RNAseq | 2.5419 | 0.0001 | |
| SRP193095 | RAB6B | 51560 | RNAseq | 0.4097 | 0.0633 | |
| SRP219564 | RAB6B | 51560 | RNAseq | -0.5122 | 0.5346 | |
| TCGA | RAB6B | 51560 | RNAseq | -0.2848 | 0.1514 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by RAB6B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RAB6B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RAB6B | 51560 | 16 | 0 | 14 | |
| GSE20123 | RAB6B | 51560 | 16 | 0 | 14 | |
| GSE43470 | RAB6B | 51560 | 21 | 0 | 22 | |
| GSE46452 | RAB6B | 51560 | 15 | 4 | 40 | |
| GSE47630 | RAB6B | 51560 | 18 | 3 | 19 | |
| GSE54993 | RAB6B | 51560 | 2 | 8 | 60 | |
| GSE54994 | RAB6B | 51560 | 32 | 1 | 20 | |
| GSE60625 | RAB6B | 51560 | 0 | 6 | 5 | |
| GSE74703 | RAB6B | 51560 | 18 | 0 | 18 | |
| GSE74704 | RAB6B | 51560 | 11 | 0 | 9 | |
| TCGA | RAB6B | 51560 | 59 | 5 | 32 |
Total number of gains: 208; Total number of losses: 27; Total Number of normals: 253.
Somatic mutations of RAB6B:
Generating mutation plots.
Highly correlated genes for RAB6B:
Showing top 20/494 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RAB6B | ATF3 | 0.766801 | 3 | 0 | 3 |
| RAB6B | CDS2 | 0.720047 | 3 | 0 | 3 |
| RAB6B | SPOCK1 | 0.697991 | 3 | 0 | 3 |
| RAB6B | TSPAN18 | 0.687907 | 9 | 0 | 8 |
| RAB6B | MEF2D | 0.686054 | 3 | 0 | 3 |
| RAB6B | BVES | 0.684078 | 4 | 0 | 4 |
| RAB6B | FLNA | 0.683885 | 4 | 0 | 3 |
| RAB6B | LIX1L | 0.683807 | 3 | 0 | 3 |
| RAB6B | NPTX1 | 0.681839 | 4 | 0 | 3 |
| RAB6B | ZXDA | 0.678573 | 3 | 0 | 3 |
| RAB6B | C5orf24 | 0.671376 | 3 | 0 | 3 |
| RAB6B | RNF150 | 0.668669 | 4 | 0 | 3 |
| RAB6B | GNPDA2 | 0.66851 | 3 | 0 | 3 |
| RAB6B | EBF1 | 0.666337 | 3 | 0 | 3 |
| RAB6B | ARHGEF25 | 0.663326 | 5 | 0 | 4 |
| RAB6B | GABRA2 | 0.661197 | 4 | 0 | 3 |
| RAB6B | RSF1 | 0.660614 | 4 | 0 | 3 |
| RAB6B | IER2 | 0.660237 | 3 | 0 | 3 |
| RAB6B | ANO5 | 0.656425 | 5 | 0 | 3 |
| RAB6B | C3orf18 | 0.655697 | 6 | 0 | 4 |
For details and further investigation, click here
