| Full name: centromere protein C | Alias Symbol: CENP-C|hcp-4|MIF2 | ||
| Type: protein-coding gene | Cytoband: 4q13.2 | ||
| Entrez ID: 1060 | HGNC ID: HGNC:1854 | Ensembl Gene: ENSG00000145241 | OMIM ID: 117141 |
Screen Evidence:
| |||
Expression of CENPC:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CENPC | 1060 | 204739_at | -0.2264 | 0.5589 | |
| GSE20347 | CENPC | 1060 | 204739_at | -0.4521 | 0.0103 | |
| GSE23400 | CENPC | 1060 | 204739_at | -0.1819 | 0.0036 | |
| GSE26886 | CENPC | 1060 | 204739_at | -0.7313 | 0.0016 | |
| GSE29001 | CENPC | 1060 | 204739_at | -0.4144 | 0.0761 | |
| GSE38129 | CENPC | 1060 | 204739_at | -0.2801 | 0.0496 | |
| GSE45670 | CENPC | 1060 | 204739_at | -0.4124 | 0.0150 | |
| GSE53622 | CENPC | 1060 | 37782 | -0.3624 | 0.0000 | |
| GSE53624 | CENPC | 1060 | 37782 | -0.5111 | 0.0000 | |
| GSE63941 | CENPC | 1060 | 204739_at | -1.0838 | 0.0478 | |
| GSE77861 | CENPC | 1060 | 204739_at | -0.0252 | 0.9549 | |
| SRP007169 | CENPC | 1060 | RNAseq | 0.0686 | 0.8828 | |
| SRP008496 | CENPC | 1060 | RNAseq | 0.3502 | 0.2186 | |
| SRP064894 | CENPC | 1060 | RNAseq | -0.6248 | 0.0050 | |
| SRP133303 | CENPC | 1060 | RNAseq | -0.2170 | 0.1507 | |
| SRP159526 | CENPC | 1060 | RNAseq | -0.6442 | 0.0139 | |
| SRP193095 | CENPC | 1060 | RNAseq | -0.4118 | 0.0017 | |
| SRP219564 | CENPC | 1060 | RNAseq | -0.7264 | 0.0718 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by CENPC expression:
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| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of CENPC:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CENPC | 1060 | 2 | 11 | 17 | |
| GSE20123 | CENPC | 1060 | 2 | 12 | 16 | |
| GSE43470 | CENPC | 1060 | 0 | 13 | 30 | |
| GSE46452 | CENPC | 1060 | 2 | 35 | 22 | |
| GSE47630 | CENPC | 1060 | 0 | 19 | 21 | |
| GSE54993 | CENPC | 1060 | 7 | 0 | 63 | |
| GSE54994 | CENPC | 1060 | 1 | 9 | 43 | |
| GSE60625 | CENPC | 1060 | 0 | 0 | 11 | |
| GSE74703 | CENPC | 1060 | 0 | 11 | 25 | |
| GSE74704 | CENPC | 1060 | 1 | 8 | 11 | |
| TCGA | CENPC | 1060 | 18 | 27 | 51 |
Total number of gains: 33; Total number of losses: 145; Total Number of normals: 310.
Somatic mutations of CENPC:
Generating mutation plots.
Highly correlated genes for CENPC:
Showing top 20/453 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CENPC | PITHD1 | 0.735454 | 3 | 0 | 3 |
| CENPC | EIF2B1 | 0.72453 | 3 | 0 | 3 |
| CENPC | COQ5 | 0.687949 | 3 | 0 | 3 |
| CENPC | ZNF506 | 0.673603 | 3 | 0 | 3 |
| CENPC | MCPH1 | 0.662984 | 3 | 0 | 3 |
| CENPC | GDAP2 | 0.654348 | 3 | 0 | 3 |
| CENPC | PTPN13 | 0.650335 | 9 | 0 | 8 |
| CENPC | EMC2 | 0.640597 | 3 | 0 | 3 |
| CENPC | YIPF1 | 0.639688 | 3 | 0 | 3 |
| CENPC | NUP54 | 0.6328 | 3 | 0 | 3 |
| CENPC | LMBRD2 | 0.63256 | 4 | 0 | 3 |
| CENPC | ERI2 | 0.631226 | 3 | 0 | 3 |
| CENPC | FAM3B | 0.627177 | 5 | 0 | 3 |
| CENPC | IMPACT | 0.626155 | 3 | 0 | 3 |
| CENPC | ZNF212 | 0.622359 | 4 | 0 | 3 |
| CENPC | AASDH | 0.621453 | 4 | 0 | 3 |
| CENPC | MOB1B | 0.620266 | 4 | 0 | 3 |
| CENPC | MAGI3 | 0.619552 | 5 | 0 | 4 |
| CENPC | ATMIN | 0.618591 | 6 | 0 | 5 |
| CENPC | ZNF823 | 0.616916 | 4 | 0 | 3 |
For details and further investigation, click here
