| Full name: ER membrane protein complex subunit 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 8q23.1 | ||
| Entrez ID: 9694 | HGNC ID: HGNC:28963 | Ensembl Gene: ENSG00000104412 | OMIM ID: 607722 |
Screen Evidence:
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Expression of EMC2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EMC2 | 9694 | 203584_at | 0.0603 | 0.9477 | |
| GSE20347 | EMC2 | 9694 | 203584_at | 0.0595 | 0.7279 | |
| GSE23400 | EMC2 | 9694 | 203584_at | 0.1602 | 0.0369 | |
| GSE26886 | EMC2 | 9694 | 203584_at | -0.6133 | 0.0055 | |
| GSE29001 | EMC2 | 9694 | 203584_at | -0.1380 | 0.7282 | |
| GSE38129 | EMC2 | 9694 | 203584_at | 0.0544 | 0.6803 | |
| GSE45670 | EMC2 | 9694 | 203584_at | 0.0185 | 0.8919 | |
| GSE53622 | EMC2 | 9694 | 12220 | -0.1213 | 0.0272 | |
| GSE53624 | EMC2 | 9694 | 12220 | -0.0498 | 0.3702 | |
| GSE63941 | EMC2 | 9694 | 203584_at | -0.1294 | 0.7738 | |
| GSE77861 | EMC2 | 9694 | 203584_at | -0.0941 | 0.7423 | |
| SRP007169 | EMC2 | 9694 | RNAseq | -0.1936 | 0.7447 | |
| SRP008496 | EMC2 | 9694 | RNAseq | -0.3223 | 0.3980 | |
| SRP064894 | EMC2 | 9694 | RNAseq | -0.0833 | 0.6836 | |
| SRP133303 | EMC2 | 9694 | RNAseq | 0.0613 | 0.6697 | |
| SRP159526 | EMC2 | 9694 | RNAseq | -0.4777 | 0.1575 | |
| SRP193095 | EMC2 | 9694 | RNAseq | -0.4203 | 0.0012 | |
| SRP219564 | EMC2 | 9694 | RNAseq | -0.4531 | 0.0791 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by EMC2 expression:
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| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of EMC2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EMC2 | 9694 | 16 | 0 | 14 | |
| GSE20123 | EMC2 | 9694 | 17 | 0 | 13 | |
| GSE43470 | EMC2 | 9694 | 22 | 0 | 21 | |
| GSE46452 | EMC2 | 9694 | 25 | 0 | 34 | |
| GSE47630 | EMC2 | 9694 | 24 | 0 | 16 | |
| GSE54993 | EMC2 | 9694 | 0 | 20 | 50 | |
| GSE54994 | EMC2 | 9694 | 37 | 1 | 15 | |
| GSE60625 | EMC2 | 9694 | 0 | 4 | 7 | |
| GSE74703 | EMC2 | 9694 | 19 | 0 | 17 | |
| GSE74704 | EMC2 | 9694 | 11 | 0 | 9 | |
| TCGA | EMC2 | 9694 | 60 | 1 | 35 |
Total number of gains: 231; Total number of losses: 26; Total Number of normals: 231.
Somatic mutations of EMC2:
Generating mutation plots.
Highly correlated genes for EMC2:
Showing top 20/52 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EMC2 | SDCBP | 0.648554 | 4 | 0 | 4 |
| EMC2 | CENPC | 0.640597 | 3 | 0 | 3 |
| EMC2 | ABI1 | 0.638998 | 3 | 0 | 3 |
| EMC2 | IDI1 | 0.636603 | 3 | 0 | 3 |
| EMC2 | CWC22 | 0.630527 | 3 | 0 | 3 |
| EMC2 | PRPF18 | 0.626563 | 4 | 0 | 3 |
| EMC2 | SERINC1 | 0.618287 | 4 | 0 | 3 |
| EMC2 | TDRD7 | 0.618028 | 3 | 0 | 3 |
| EMC2 | BNIP3L | 0.615798 | 3 | 0 | 3 |
| EMC2 | PEX2 | 0.604828 | 6 | 0 | 5 |
| EMC2 | TRAPPC11 | 0.598814 | 4 | 0 | 3 |
| EMC2 | CD2AP | 0.593295 | 3 | 0 | 3 |
| EMC2 | YIPF4 | 0.588654 | 5 | 0 | 3 |
| EMC2 | RCHY1 | 0.584559 | 3 | 0 | 3 |
| EMC2 | PPP1R2 | 0.584543 | 5 | 0 | 4 |
| EMC2 | HIBCH | 0.581127 | 3 | 0 | 3 |
| EMC2 | RIOK2 | 0.579787 | 4 | 0 | 3 |
| EMC2 | RMDN1 | 0.576656 | 6 | 0 | 3 |
| EMC2 | CSNK1A1 | 0.575359 | 3 | 0 | 3 |
| EMC2 | VPS13B | 0.567905 | 7 | 0 | 5 |
For details and further investigation, click here
