| Full name: ectonucleoside triphosphate diphosphohydrolase 4 | Alias Symbol: LALP70|LAP70|KIAA0392|NTPDase-4|UDPase | ||
| Type: protein-coding gene | Cytoband: 8p21.3 | ||
| Entrez ID: 9583 | HGNC ID: HGNC:14573 | Ensembl Gene: ENSG00000197217 | OMIM ID: 607577 |
| Drug and gene relationship at DGIdb | |||
Expression of ENTPD4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ENTPD4 | 9583 | 204076_at | 0.1941 | 0.5722 | |
| GSE20347 | ENTPD4 | 9583 | 204076_at | 0.2253 | 0.2396 | |
| GSE23400 | ENTPD4 | 9583 | 204076_at | 0.2783 | 0.0039 | |
| GSE26886 | ENTPD4 | 9583 | 204076_at | 0.3326 | 0.2667 | |
| GSE29001 | ENTPD4 | 9583 | 204076_at | 0.0689 | 0.8502 | |
| GSE38129 | ENTPD4 | 9583 | 204076_at | 0.0994 | 0.5092 | |
| GSE45670 | ENTPD4 | 9583 | 204076_at | 0.0986 | 0.6630 | |
| GSE53622 | ENTPD4 | 9583 | 105160 | 0.2864 | 0.0000 | |
| GSE53624 | ENTPD4 | 9583 | 105160 | -0.2589 | 0.0001 | |
| GSE63941 | ENTPD4 | 9583 | 204076_at | -1.1426 | 0.0046 | |
| GSE77861 | ENTPD4 | 9583 | 204076_at | 0.5941 | 0.2456 | |
| GSE97050 | ENTPD4 | 9583 | A_23_P216017 | 0.3983 | 0.2616 | |
| SRP007169 | ENTPD4 | 9583 | RNAseq | 0.1992 | 0.5955 | |
| SRP008496 | ENTPD4 | 9583 | RNAseq | 0.6775 | 0.0096 | |
| SRP064894 | ENTPD4 | 9583 | RNAseq | 0.1195 | 0.5841 | |
| SRP133303 | ENTPD4 | 9583 | RNAseq | 0.1057 | 0.4678 | |
| SRP159526 | ENTPD4 | 9583 | RNAseq | 0.1158 | 0.6265 | |
| SRP193095 | ENTPD4 | 9583 | RNAseq | 0.0110 | 0.9296 | |
| SRP219564 | ENTPD4 | 9583 | RNAseq | 0.0393 | 0.8721 | |
| TCGA | ENTPD4 | 9583 | RNAseq | -0.2021 | 0.0006 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by ENTPD4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ENTPD4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ENTPD4 | 9583 | 4 | 12 | 14 | |
| GSE20123 | ENTPD4 | 9583 | 4 | 12 | 14 | |
| GSE43470 | ENTPD4 | 9583 | 4 | 9 | 30 | |
| GSE46452 | ENTPD4 | 9583 | 13 | 13 | 33 | |
| GSE47630 | ENTPD4 | 9583 | 10 | 8 | 22 | |
| GSE54993 | ENTPD4 | 9583 | 2 | 14 | 54 | |
| GSE54994 | ENTPD4 | 9583 | 8 | 18 | 27 | |
| GSE60625 | ENTPD4 | 9583 | 3 | 0 | 8 | |
| GSE74703 | ENTPD4 | 9583 | 4 | 7 | 25 | |
| GSE74704 | ENTPD4 | 9583 | 3 | 8 | 9 | |
| TCGA | ENTPD4 | 9583 | 15 | 42 | 39 |
Total number of gains: 70; Total number of losses: 143; Total Number of normals: 275.
Somatic mutations of ENTPD4:
Generating mutation plots.
Highly correlated genes for ENTPD4:
Showing top 20/379 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ENTPD4 | ENG | 0.842324 | 3 | 0 | 3 |
| ENTPD4 | RICTOR | 0.805178 | 3 | 0 | 3 |
| ENTPD4 | TUBE1 | 0.794531 | 3 | 0 | 3 |
| ENTPD4 | SH2B3 | 0.786717 | 3 | 0 | 3 |
| ENTPD4 | LMAN1 | 0.76557 | 3 | 0 | 3 |
| ENTPD4 | CLDN12 | 0.762282 | 4 | 0 | 3 |
| ENTPD4 | STK32B | 0.741898 | 3 | 0 | 3 |
| ENTPD4 | TMX3 | 0.739247 | 3 | 0 | 3 |
| ENTPD4 | FNIP1 | 0.732813 | 3 | 0 | 3 |
| ENTPD4 | HVCN1 | 0.727337 | 3 | 0 | 3 |
| ENTPD4 | RARS2 | 0.720633 | 3 | 0 | 3 |
| ENTPD4 | FAM160B1 | 0.71828 | 3 | 0 | 3 |
| ENTPD4 | SVEP1 | 0.717277 | 3 | 0 | 3 |
| ENTPD4 | SETX | 0.715628 | 3 | 0 | 3 |
| ENTPD4 | IGFBP4 | 0.713357 | 4 | 0 | 4 |
| ENTPD4 | GIMAP4 | 0.712493 | 3 | 0 | 3 |
| ENTPD4 | MCAM | 0.706902 | 3 | 0 | 3 |
| ENTPD4 | POU5F2 | 0.703252 | 3 | 0 | 3 |
| ENTPD4 | MMP3 | 0.702766 | 4 | 0 | 4 |
| ENTPD4 | CEP85L | 0.702745 | 3 | 0 | 3 |
For details and further investigation, click here
