| Full name: complement factor H related 2 | Alias Symbol: FHR2 | ||
| Type: protein-coding gene | Cytoband: 1q31.3 | ||
| Entrez ID: 3080 | HGNC ID: HGNC:4890 | Ensembl Gene: ENSG00000080910 | OMIM ID: 600889 |
| Drug and gene relationship at DGIdb | |||
Expression of CFHR2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CFHR2 | 3080 | 206910_x_at | -0.3139 | 0.3932 | |
| GSE20347 | CFHR2 | 3080 | 206910_x_at | 0.0158 | 0.8835 | |
| GSE23400 | CFHR2 | 3080 | 206910_x_at | -0.0419 | 0.3871 | |
| GSE26886 | CFHR2 | 3080 | 206910_x_at | -0.0600 | 0.7829 | |
| GSE29001 | CFHR2 | 3080 | 206910_x_at | 0.2550 | 0.2025 | |
| GSE38129 | CFHR2 | 3080 | 206910_x_at | -0.2087 | 0.0614 | |
| GSE45670 | CFHR2 | 3080 | 206910_x_at | -0.5709 | 0.0098 | |
| GSE63941 | CFHR2 | 3080 | 206910_x_at | -1.2133 | 0.0014 | |
| GSE77861 | CFHR2 | 3080 | 206910_x_at | -0.0814 | 0.3390 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by CFHR2 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of CFHR2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CFHR2 | 3080 | 6 | 1 | 23 | |
| GSE20123 | CFHR2 | 3080 | 6 | 1 | 23 | |
| GSE43470 | CFHR2 | 3080 | 5 | 1 | 37 | |
| GSE46452 | CFHR2 | 3080 | 3 | 1 | 55 | |
| GSE47630 | CFHR2 | 3080 | 14 | 0 | 26 | |
| GSE54993 | CFHR2 | 3080 | 0 | 6 | 64 | |
| GSE54994 | CFHR2 | 3080 | 16 | 0 | 37 | |
| GSE60625 | CFHR2 | 3080 | 0 | 0 | 11 | |
| GSE74703 | CFHR2 | 3080 | 5 | 1 | 30 | |
| GSE74704 | CFHR2 | 3080 | 2 | 1 | 17 | |
| TCGA | CFHR2 | 3080 | 41 | 6 | 49 |
Total number of gains: 98; Total number of losses: 18; Total Number of normals: 372.
Somatic mutations of CFHR2:
Generating mutation plots.
Highly correlated genes for CFHR2:
Showing top 20/287 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CFHR2 | LRRN4CL | 0.713118 | 3 | 0 | 3 |
| CFHR2 | ATOH8 | 0.709342 | 3 | 0 | 3 |
| CFHR2 | TESC | 0.6937 | 3 | 0 | 3 |
| CFHR2 | GALNT15 | 0.692708 | 3 | 0 | 3 |
| CFHR2 | GNG2 | 0.691277 | 3 | 0 | 3 |
| CFHR2 | CFH | 0.678149 | 9 | 0 | 8 |
| CFHR2 | SCARA5 | 0.66338 | 3 | 0 | 3 |
| CFHR2 | LINC01279 | 0.661783 | 4 | 0 | 4 |
| CFHR2 | ENTPD1 | 0.658862 | 6 | 0 | 6 |
| CFHR2 | CLDN11 | 0.648381 | 4 | 0 | 4 |
| CFHR2 | RSPO1 | 0.646658 | 3 | 0 | 3 |
| CFHR2 | KCNT2 | 0.644474 | 4 | 0 | 3 |
| CFHR2 | CCDC80 | 0.640904 | 4 | 0 | 4 |
| CFHR2 | GSTM5 | 0.637056 | 5 | 0 | 4 |
| CFHR2 | SLC26A4 | 0.630684 | 3 | 0 | 3 |
| CFHR2 | ANKRD44 | 0.62971 | 4 | 0 | 3 |
| CFHR2 | PAMR1 | 0.628689 | 5 | 0 | 4 |
| CFHR2 | PLCB4 | 0.628402 | 3 | 0 | 3 |
| CFHR2 | F10 | 0.627702 | 4 | 0 | 4 |
| CFHR2 | LDB2 | 0.627683 | 7 | 0 | 6 |
For details and further investigation, click here
