| Full name: solute carrier family 26 member 4 | Alias Symbol: PDS | ||
| Type: protein-coding gene | Cytoband: 7q22.3 | ||
| Entrez ID: 5172 | HGNC ID: HGNC:8818 | Ensembl Gene: ENSG00000091137 | OMIM ID: 605646 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC26A4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC26A4 | 5172 | 206529_x_at | 0.0036 | 0.9892 | |
| GSE20347 | SLC26A4 | 5172 | 206529_x_at | 0.0647 | 0.2994 | |
| GSE23400 | SLC26A4 | 5172 | 206529_x_at | -0.0070 | 0.7389 | |
| GSE26886 | SLC26A4 | 5172 | 206529_x_at | -0.0480 | 0.7658 | |
| GSE29001 | SLC26A4 | 5172 | 206529_x_at | 0.0365 | 0.7916 | |
| GSE38129 | SLC26A4 | 5172 | 206529_x_at | -0.0410 | 0.5911 | |
| GSE45670 | SLC26A4 | 5172 | 206529_x_at | 0.1083 | 0.7589 | |
| GSE53622 | SLC26A4 | 5172 | 15338 | -0.3124 | 0.0671 | |
| GSE53624 | SLC26A4 | 5172 | 15338 | -0.2983 | 0.0827 | |
| GSE63941 | SLC26A4 | 5172 | 206529_x_at | -0.2787 | 0.0428 | |
| GSE77861 | SLC26A4 | 5172 | 206529_x_at | 0.0256 | 0.8378 | |
| SRP133303 | SLC26A4 | 5172 | RNAseq | -0.1169 | 0.6816 | |
| TCGA | SLC26A4 | 5172 | RNAseq | -0.9944 | 0.0052 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SLC26A4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC26A4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC26A4 | 5172 | 12 | 0 | 18 | |
| GSE20123 | SLC26A4 | 5172 | 12 | 0 | 18 | |
| GSE43470 | SLC26A4 | 5172 | 6 | 2 | 35 | |
| GSE46452 | SLC26A4 | 5172 | 10 | 1 | 48 | |
| GSE47630 | SLC26A4 | 5172 | 8 | 3 | 29 | |
| GSE54993 | SLC26A4 | 5172 | 2 | 9 | 59 | |
| GSE54994 | SLC26A4 | 5172 | 16 | 3 | 34 | |
| GSE60625 | SLC26A4 | 5172 | 0 | 0 | 11 | |
| GSE74703 | SLC26A4 | 5172 | 6 | 2 | 28 | |
| GSE74704 | SLC26A4 | 5172 | 8 | 0 | 12 | |
| TCGA | SLC26A4 | 5172 | 50 | 10 | 36 |
Total number of gains: 130; Total number of losses: 30; Total Number of normals: 328.
Somatic mutations of SLC26A4:
Generating mutation plots.
Highly correlated genes for SLC26A4:
Showing top 20/78 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC26A4 | PRPS1L1 | 0.647697 | 4 | 0 | 4 |
| SLC26A4 | ZC3H12D | 0.634057 | 3 | 0 | 3 |
| SLC26A4 | CFHR2 | 0.630684 | 3 | 0 | 3 |
| SLC26A4 | KSR1 | 0.610634 | 4 | 0 | 4 |
| SLC26A4 | CXCL11 | 0.603412 | 3 | 0 | 3 |
| SLC26A4 | XYLB | 0.599311 | 4 | 0 | 4 |
| SLC26A4 | TAP2 | 0.594463 | 3 | 0 | 3 |
| SLC26A4 | MTAP | 0.59119 | 3 | 0 | 3 |
| SLC26A4 | CDH10 | 0.590245 | 5 | 0 | 4 |
| SLC26A4 | PLA1A | 0.589751 | 6 | 0 | 5 |
| SLC26A4 | SYT12 | 0.588169 | 4 | 0 | 3 |
| SLC26A4 | CCDC144A | 0.587972 | 4 | 0 | 4 |
| SLC26A4 | DNAH3 | 0.587942 | 4 | 0 | 3 |
| SLC26A4 | AFF3 | 0.584716 | 3 | 0 | 3 |
| SLC26A4 | ATG10 | 0.583233 | 4 | 0 | 3 |
| SLC26A4 | ACKR4 | 0.581694 | 6 | 0 | 5 |
| SLC26A4 | IL17A | 0.580572 | 5 | 0 | 4 |
| SLC26A4 | MILR1 | 0.576419 | 4 | 0 | 3 |
| SLC26A4 | CCL23 | 0.576385 | 4 | 0 | 3 |
| SLC26A4 | HPCAL4 | 0.575661 | 4 | 0 | 3 |
For details and further investigation, click here
