| Full name: complement factor H related 4 | Alias Symbol: FHR-4|FHR4 | ||
| Type: protein-coding gene | Cytoband: 1q31.3 | ||
| Entrez ID: 10877 | HGNC ID: HGNC:16979 | Ensembl Gene: ENSG00000134365 | OMIM ID: 605337 |
| Drug and gene relationship at DGIdb | |||
Expression of CFHR4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CFHR4 | 10877 | 207874_s_at | 0.7625 | 0.3794 | |
| GSE20347 | CFHR4 | 10877 | 207874_s_at | 0.5413 | 0.0147 | |
| GSE23400 | CFHR4 | 10877 | 207874_s_at | 0.0233 | 0.5222 | |
| GSE26886 | CFHR4 | 10877 | 207874_s_at | 0.7761 | 0.0282 | |
| GSE29001 | CFHR4 | 10877 | 207874_s_at | 0.5432 | 0.0517 | |
| GSE38129 | CFHR4 | 10877 | 207874_s_at | 0.3286 | 0.0697 | |
| GSE45670 | CFHR4 | 10877 | 207874_s_at | 0.5947 | 0.0127 | |
| GSE53622 | CFHR4 | 10877 | 6035 | 1.4262 | 0.0000 | |
| GSE53624 | CFHR4 | 10877 | 6035 | 2.4794 | 0.0000 | |
| GSE63941 | CFHR4 | 10877 | 207874_s_at | 1.4021 | 0.0770 | |
| GSE77861 | CFHR4 | 10877 | 207874_s_at | 0.0937 | 0.6352 | |
| TCGA | CFHR4 | 10877 | RNAseq | 3.1673 | 0.0007 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by CFHR4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CFHR4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CFHR4 | 10877 | 6 | 1 | 23 | |
| GSE20123 | CFHR4 | 10877 | 6 | 1 | 23 | |
| GSE43470 | CFHR4 | 10877 | 5 | 1 | 37 | |
| GSE46452 | CFHR4 | 10877 | 3 | 1 | 55 | |
| GSE47630 | CFHR4 | 10877 | 14 | 0 | 26 | |
| GSE54993 | CFHR4 | 10877 | 0 | 6 | 64 | |
| GSE54994 | CFHR4 | 10877 | 16 | 0 | 37 | |
| GSE60625 | CFHR4 | 10877 | 0 | 0 | 11 | |
| GSE74703 | CFHR4 | 10877 | 5 | 1 | 30 | |
| GSE74704 | CFHR4 | 10877 | 2 | 1 | 17 | |
| TCGA | CFHR4 | 10877 | 41 | 6 | 49 |
Total number of gains: 98; Total number of losses: 18; Total Number of normals: 372.
Somatic mutations of CFHR4:
Generating mutation plots.
Highly correlated genes for CFHR4:
Showing top 20/115 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CFHR4 | CHD3 | 0.65258 | 3 | 0 | 3 |
| CFHR4 | SH2D2A | 0.644711 | 4 | 0 | 3 |
| CFHR4 | GAS2L3 | 0.644706 | 3 | 0 | 3 |
| CFHR4 | HAGLROS | 0.637475 | 5 | 0 | 5 |
| CFHR4 | LINC01116 | 0.627223 | 3 | 0 | 3 |
| CFHR4 | MTDH | 0.625608 | 4 | 0 | 3 |
| CFHR4 | RPAIN | 0.61924 | 3 | 0 | 3 |
| CFHR4 | PRR15 | 0.611156 | 3 | 0 | 3 |
| CFHR4 | C17orf100 | 0.608495 | 3 | 0 | 3 |
| CFHR4 | DHX36 | 0.604295 | 4 | 0 | 3 |
| CFHR4 | HOXD8 | 0.602655 | 5 | 0 | 3 |
| CFHR4 | ACVR1C | 0.59921 | 4 | 0 | 4 |
| CFHR4 | C2orf69 | 0.594488 | 3 | 0 | 3 |
| CFHR4 | LINC01049 | 0.593662 | 4 | 0 | 3 |
| CFHR4 | SLC3A2 | 0.593259 | 4 | 0 | 3 |
| CFHR4 | RRS1 | 0.59194 | 4 | 0 | 3 |
| CFHR4 | TCF24 | 0.590844 | 5 | 0 | 3 |
| CFHR4 | CEL | 0.589557 | 5 | 0 | 3 |
| CFHR4 | CCNE2 | 0.588726 | 6 | 0 | 5 |
| CFHR4 | ODC1 | 0.584531 | 4 | 0 | 3 |
For details and further investigation, click here
