| Full name: solute carrier family 3 member 2 | Alias Symbol: 4T2HC|4F2|NACAE|CD98|CD98HC|4F2HC | ||
| Type: protein-coding gene | Cytoband: 11q12.3 | ||
| Entrez ID: 6520 | HGNC ID: HGNC:11026 | Ensembl Gene: ENSG00000168003 | OMIM ID: 158070 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of SLC3A2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC3A2 | 6520 | 200924_s_at | 0.8409 | 0.1839 | |
| GSE20347 | SLC3A2 | 6520 | 200924_s_at | 1.0898 | 0.0000 | |
| GSE23400 | SLC3A2 | 6520 | 200924_s_at | 0.9376 | 0.0000 | |
| GSE26886 | SLC3A2 | 6520 | 200924_s_at | 0.5627 | 0.0295 | |
| GSE29001 | SLC3A2 | 6520 | 200924_s_at | 0.7873 | 0.0158 | |
| GSE38129 | SLC3A2 | 6520 | 200924_s_at | 1.2191 | 0.0000 | |
| GSE45670 | SLC3A2 | 6520 | 200924_s_at | 0.9823 | 0.0007 | |
| GSE53622 | SLC3A2 | 6520 | 16499 | 1.2824 | 0.0000 | |
| GSE53624 | SLC3A2 | 6520 | 16499 | 1.2765 | 0.0000 | |
| GSE63941 | SLC3A2 | 6520 | 200924_s_at | 2.3188 | 0.0072 | |
| GSE77861 | SLC3A2 | 6520 | 200924_s_at | 1.3906 | 0.0011 | |
| GSE97050 | SLC3A2 | 6520 | A_23_P75811 | 1.0219 | 0.1239 | |
| SRP007169 | SLC3A2 | 6520 | RNAseq | 2.0149 | 0.0000 | |
| SRP008496 | SLC3A2 | 6520 | RNAseq | 2.1206 | 0.0000 | |
| SRP064894 | SLC3A2 | 6520 | RNAseq | 1.0824 | 0.0000 | |
| SRP133303 | SLC3A2 | 6520 | RNAseq | 1.4001 | 0.0000 | |
| SRP159526 | SLC3A2 | 6520 | RNAseq | 1.3350 | 0.0000 | |
| SRP193095 | SLC3A2 | 6520 | RNAseq | 1.2486 | 0.0000 | |
| SRP219564 | SLC3A2 | 6520 | RNAseq | 1.0906 | 0.0249 | |
| TCGA | SLC3A2 | 6520 | RNAseq | 0.3784 | 0.0000 |
Upregulated datasets: 13; Downregulated datasets: 0.
Survival by SLC3A2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC3A2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC3A2 | 6520 | 6 | 5 | 19 | |
| GSE20123 | SLC3A2 | 6520 | 6 | 5 | 19 | |
| GSE43470 | SLC3A2 | 6520 | 1 | 6 | 36 | |
| GSE46452 | SLC3A2 | 6520 | 8 | 4 | 47 | |
| GSE47630 | SLC3A2 | 6520 | 3 | 7 | 30 | |
| GSE54993 | SLC3A2 | 6520 | 3 | 0 | 67 | |
| GSE54994 | SLC3A2 | 6520 | 5 | 5 | 43 | |
| GSE60625 | SLC3A2 | 6520 | 0 | 3 | 8 | |
| GSE74703 | SLC3A2 | 6520 | 1 | 3 | 32 | |
| GSE74704 | SLC3A2 | 6520 | 4 | 3 | 13 | |
| TCGA | SLC3A2 | 6520 | 15 | 11 | 70 |
Total number of gains: 52; Total number of losses: 52; Total Number of normals: 384.
Somatic mutations of SLC3A2:
Generating mutation plots.
Highly correlated genes for SLC3A2:
Showing top 20/1828 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC3A2 | XPR1 | 0.778043 | 7 | 0 | 6 |
| SLC3A2 | TENM2 | 0.774264 | 5 | 0 | 5 |
| SLC3A2 | FAM89A | 0.770991 | 3 | 0 | 3 |
| SLC3A2 | SLC25A17 | 0.768578 | 8 | 0 | 8 |
| SLC3A2 | EBNA1BP2 | 0.767737 | 3 | 0 | 3 |
| SLC3A2 | CLSPN | 0.763262 | 6 | 0 | 6 |
| SLC3A2 | NOP56 | 0.761528 | 3 | 0 | 3 |
| SLC3A2 | CDCA2 | 0.749547 | 4 | 0 | 4 |
| SLC3A2 | TPX2 | 0.744185 | 12 | 0 | 11 |
| SLC3A2 | GALNT18 | 0.739956 | 6 | 0 | 6 |
| SLC3A2 | PLAU | 0.739381 | 10 | 0 | 10 |
| SLC3A2 | ALPK2 | 0.737349 | 3 | 0 | 3 |
| SLC3A2 | BLACAT1 | 0.734413 | 3 | 0 | 3 |
| SLC3A2 | SNRPB | 0.734293 | 10 | 0 | 10 |
| SLC3A2 | ATP1B3 | 0.734249 | 10 | 0 | 10 |
| SLC3A2 | FOXN2 | 0.733723 | 6 | 0 | 6 |
| SLC3A2 | NLN | 0.732046 | 3 | 0 | 3 |
| SLC3A2 | NUDT1 | 0.730745 | 11 | 0 | 10 |
| SLC3A2 | LRP12 | 0.730461 | 11 | 0 | 11 |
| SLC3A2 | PLK1 | 0.727362 | 11 | 0 | 11 |
For details and further investigation, click here
