| Full name: cell growth regulator with EF-hand domain 1 | Alias Symbol: CGR11 | ||
| Type: protein-coding gene | Cytoband: 2p23.3 | ||
| Entrez ID: 10669 | HGNC ID: HGNC:16962 | Ensembl Gene: ENSG00000138028 | OMIM ID: 606137 |
| Drug and gene relationship at DGIdb | |||
Expression of CGREF1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CGREF1 | 10669 | 205937_at | -0.2723 | 0.4239 | |
| GSE20347 | CGREF1 | 10669 | 205937_at | 0.0662 | 0.5378 | |
| GSE23400 | CGREF1 | 10669 | 205937_at | -0.1263 | 0.0001 | |
| GSE26886 | CGREF1 | 10669 | 205937_at | 0.0991 | 0.4886 | |
| GSE29001 | CGREF1 | 10669 | 205937_at | 0.0285 | 0.8834 | |
| GSE38129 | CGREF1 | 10669 | 205937_at | 0.1823 | 0.1484 | |
| GSE45670 | CGREF1 | 10669 | 205937_at | 0.0255 | 0.9261 | |
| GSE53622 | CGREF1 | 10669 | 92820 | 0.6807 | 0.0001 | |
| GSE53624 | CGREF1 | 10669 | 92820 | 0.2962 | 0.0056 | |
| GSE63941 | CGREF1 | 10669 | 205937_at | -0.2907 | 0.4577 | |
| GSE77861 | CGREF1 | 10669 | 205937_at | -0.1467 | 0.2911 | |
| GSE97050 | CGREF1 | 10669 | A_33_P3281850 | 0.4133 | 0.2641 | |
| SRP064894 | CGREF1 | 10669 | RNAseq | -0.0366 | 0.9352 | |
| SRP133303 | CGREF1 | 10669 | RNAseq | -0.4472 | 0.1851 | |
| SRP159526 | CGREF1 | 10669 | RNAseq | 1.6925 | 0.0010 | |
| SRP193095 | CGREF1 | 10669 | RNAseq | 0.5859 | 0.1289 | |
| SRP219564 | CGREF1 | 10669 | RNAseq | 2.0081 | 0.0027 | |
| TCGA | CGREF1 | 10669 | RNAseq | -0.0583 | 0.8126 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by CGREF1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CGREF1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CGREF1 | 10669 | 11 | 2 | 17 | |
| GSE20123 | CGREF1 | 10669 | 11 | 2 | 17 | |
| GSE43470 | CGREF1 | 10669 | 3 | 1 | 39 | |
| GSE46452 | CGREF1 | 10669 | 3 | 4 | 52 | |
| GSE47630 | CGREF1 | 10669 | 8 | 0 | 32 | |
| GSE54993 | CGREF1 | 10669 | 0 | 6 | 64 | |
| GSE54994 | CGREF1 | 10669 | 10 | 0 | 43 | |
| GSE60625 | CGREF1 | 10669 | 0 | 3 | 8 | |
| GSE74703 | CGREF1 | 10669 | 3 | 0 | 33 | |
| GSE74704 | CGREF1 | 10669 | 9 | 1 | 10 | |
| TCGA | CGREF1 | 10669 | 37 | 2 | 57 |
Total number of gains: 95; Total number of losses: 21; Total Number of normals: 372.
Somatic mutations of CGREF1:
Generating mutation plots.
Highly correlated genes for CGREF1:
Showing top 20/25 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CGREF1 | KLK4 | 0.697726 | 3 | 0 | 3 |
| CGREF1 | MEGF10 | 0.679048 | 3 | 0 | 3 |
| CGREF1 | BRSK1 | 0.660406 | 3 | 0 | 3 |
| CGREF1 | CD300LG | 0.646875 | 3 | 0 | 3 |
| CGREF1 | RGL4 | 0.633133 | 3 | 0 | 3 |
| CGREF1 | SLC22A31 | 0.632057 | 3 | 0 | 3 |
| CGREF1 | C3orf35 | 0.625512 | 3 | 0 | 3 |
| CGREF1 | BTBD8 | 0.584687 | 4 | 0 | 3 |
| CGREF1 | TNFRSF14 | 0.584301 | 3 | 0 | 3 |
| CGREF1 | SLC13A4 | 0.58107 | 4 | 0 | 3 |
| CGREF1 | CEACAM1 | 0.57052 | 4 | 0 | 3 |
| CGREF1 | ARSF | 0.56341 | 3 | 0 | 3 |
| CGREF1 | RAP1GAP | 0.556442 | 4 | 0 | 3 |
| CGREF1 | PROCA1 | 0.554897 | 4 | 0 | 3 |
| CGREF1 | KANK3 | 0.550336 | 5 | 0 | 3 |
| CGREF1 | PNPLA7 | 0.54569 | 4 | 0 | 3 |
| CGREF1 | RXFP3 | 0.542572 | 4 | 0 | 3 |
| CGREF1 | TMEM108 | 0.542555 | 3 | 0 | 3 |
| CGREF1 | GPR157 | 0.539428 | 3 | 0 | 3 |
| CGREF1 | KCNA7 | 0.538432 | 5 | 0 | 3 |
For details and further investigation, click here
