| Full name: coiled-coil-helix-coiled-coil-helix domain containing 10 | Alias Symbol: N27C7-4|MIX17A | ||
| Type: protein-coding gene | Cytoband: 22q11.23 | ||
| Entrez ID: 400916 | HGNC ID: HGNC:15559 | Ensembl Gene: ENSG00000250479 | OMIM ID: 615903 |
| Drug and gene relationship at DGIdb | |||
Expression of CHCHD10:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CHCHD10 | 400916 | 224932_at | -0.2235 | 0.6055 | |
| GSE26886 | CHCHD10 | 400916 | 224932_at | 0.0353 | 0.8866 | |
| GSE45670 | CHCHD10 | 400916 | 224932_at | 0.0498 | 0.8983 | |
| GSE63941 | CHCHD10 | 400916 | 224932_at | 2.2193 | 0.0474 | |
| GSE77861 | CHCHD10 | 400916 | 224932_at | -0.2401 | 0.6907 | |
| GSE97050 | CHCHD10 | 400916 | A_24_P6083 | -0.5433 | 0.3263 | |
| SRP007169 | CHCHD10 | 400916 | RNAseq | -0.1351 | 0.7650 | |
| SRP008496 | CHCHD10 | 400916 | RNAseq | -0.5993 | 0.0316 | |
| SRP064894 | CHCHD10 | 400916 | RNAseq | -0.0512 | 0.9139 | |
| SRP133303 | CHCHD10 | 400916 | RNAseq | -0.0525 | 0.8043 | |
| SRP159526 | CHCHD10 | 400916 | RNAseq | 0.1956 | 0.6222 | |
| SRP193095 | CHCHD10 | 400916 | RNAseq | -0.3302 | 0.0481 | |
| SRP219564 | CHCHD10 | 400916 | RNAseq | 0.0697 | 0.9168 | |
| TCGA | CHCHD10 | 400916 | RNAseq | -0.2115 | 0.0108 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by CHCHD10 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of CHCHD10:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CHCHD10 | 400916 | 5 | 7 | 18 | |
| GSE20123 | CHCHD10 | 400916 | 5 | 6 | 19 | |
| GSE43470 | CHCHD10 | 400916 | 3 | 6 | 34 | |
| GSE46452 | CHCHD10 | 400916 | 32 | 1 | 26 | |
| GSE47630 | CHCHD10 | 400916 | 8 | 5 | 27 | |
| GSE54993 | CHCHD10 | 400916 | 3 | 6 | 61 | |
| GSE54994 | CHCHD10 | 400916 | 11 | 7 | 35 | |
| GSE60625 | CHCHD10 | 400916 | 5 | 0 | 6 | |
| GSE74703 | CHCHD10 | 400916 | 3 | 5 | 28 | |
| GSE74704 | CHCHD10 | 400916 | 2 | 3 | 15 | |
| TCGA | CHCHD10 | 400916 | 26 | 15 | 55 |
Total number of gains: 103; Total number of losses: 61; Total Number of normals: 324.
Somatic mutations of CHCHD10:
Generating mutation plots.
Highly correlated genes for CHCHD10:
Showing top 20/90 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CHCHD10 | GBA2 | 0.842918 | 3 | 0 | 3 |
| CHCHD10 | POU6F1 | 0.78381 | 3 | 0 | 3 |
| CHCHD10 | ID2 | 0.781489 | 3 | 0 | 3 |
| CHCHD10 | CRY2 | 0.781129 | 3 | 0 | 3 |
| CHCHD10 | EMD | 0.781058 | 3 | 0 | 3 |
| CHCHD10 | PIGP | 0.7642 | 3 | 0 | 3 |
| CHCHD10 | APOBEC2 | 0.761943 | 3 | 0 | 3 |
| CHCHD10 | ALDH1A2 | 0.746719 | 3 | 0 | 3 |
| CHCHD10 | SUCLG1 | 0.716736 | 3 | 0 | 3 |
| CHCHD10 | PLEKHB1 | 0.706524 | 3 | 0 | 3 |
| CHCHD10 | ZNF208 | 0.703059 | 3 | 0 | 3 |
| CHCHD10 | RBP2 | 0.698065 | 3 | 0 | 3 |
| CHCHD10 | SOBP | 0.697049 | 3 | 0 | 3 |
| CHCHD10 | SIK1 | 0.691842 | 3 | 0 | 3 |
| CHCHD10 | JPH2 | 0.688943 | 3 | 0 | 3 |
| CHCHD10 | TSC22D3 | 0.68667 | 3 | 0 | 3 |
| CHCHD10 | PMF1 | 0.684076 | 3 | 0 | 3 |
| CHCHD10 | SRSF7 | 0.680958 | 3 | 0 | 3 |
| CHCHD10 | DEDD | 0.67926 | 3 | 0 | 3 |
| CHCHD10 | NELL1 | 0.676476 | 3 | 0 | 3 |
For details and further investigation, click here
