| Full name: cholinergic receptor nicotinic gamma subunit | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 2q37.1 | ||
| Entrez ID: 1146 | HGNC ID: HGNC:1967 | Ensembl Gene: ENSG00000196811 | OMIM ID: 100730 |
| Drug and gene relationship at DGIdb | |||
Expression of CHRNG:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CHRNG | 1146 | 221355_at | -0.3210 | 0.1658 | |
| GSE20347 | CHRNG | 1146 | 221355_at | 0.0856 | 0.4096 | |
| GSE23400 | CHRNG | 1146 | 221355_at | -0.1946 | 0.0000 | |
| GSE26886 | CHRNG | 1146 | 221355_at | 0.0510 | 0.7026 | |
| GSE29001 | CHRNG | 1146 | 221355_at | 0.0468 | 0.8276 | |
| GSE38129 | CHRNG | 1146 | 221355_at | -0.0787 | 0.3415 | |
| GSE45670 | CHRNG | 1146 | 221355_at | 0.0505 | 0.5856 | |
| GSE53622 | CHRNG | 1146 | 56305 | 0.2423 | 0.0752 | |
| GSE53624 | CHRNG | 1146 | 56305 | 0.3011 | 0.0018 | |
| GSE63941 | CHRNG | 1146 | 221355_at | -0.0550 | 0.7440 | |
| GSE77861 | CHRNG | 1146 | 221355_at | -0.1452 | 0.2626 | |
| SRP007169 | CHRNG | 1146 | RNAseq | -1.4232 | 0.0157 | |
| SRP133303 | CHRNG | 1146 | RNAseq | 0.1495 | 0.3708 | |
| SRP159526 | CHRNG | 1146 | RNAseq | 0.5844 | 0.2031 | |
| SRP193095 | CHRNG | 1146 | RNAseq | 0.1233 | 0.3716 | |
| SRP219564 | CHRNG | 1146 | RNAseq | 0.8106 | 0.0211 | |
| TCGA | CHRNG | 1146 | RNAseq | -0.3107 | 0.4282 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by CHRNG expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CHRNG:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CHRNG | 1146 | 1 | 12 | 17 | |
| GSE20123 | CHRNG | 1146 | 1 | 12 | 17 | |
| GSE43470 | CHRNG | 1146 | 1 | 8 | 34 | |
| GSE46452 | CHRNG | 1146 | 0 | 5 | 54 | |
| GSE47630 | CHRNG | 1146 | 4 | 5 | 31 | |
| GSE54993 | CHRNG | 1146 | 3 | 2 | 65 | |
| GSE54994 | CHRNG | 1146 | 6 | 10 | 37 | |
| GSE60625 | CHRNG | 1146 | 0 | 3 | 8 | |
| GSE74703 | CHRNG | 1146 | 1 | 6 | 29 | |
| GSE74704 | CHRNG | 1146 | 1 | 5 | 14 | |
| TCGA | CHRNG | 1146 | 11 | 29 | 56 |
Total number of gains: 29; Total number of losses: 97; Total Number of normals: 362.
Somatic mutations of CHRNG:
Generating mutation plots.
Highly correlated genes for CHRNG:
Showing top 20/550 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CHRNG | SPAG8 | 0.742347 | 3 | 0 | 3 |
| CHRNG | FGFR1 | 0.739616 | 3 | 0 | 3 |
| CHRNG | SNPH | 0.701759 | 3 | 0 | 3 |
| CHRNG | SYT13 | 0.6878 | 3 | 0 | 3 |
| CHRNG | TMEM8B | 0.682066 | 3 | 0 | 3 |
| CHRNG | LIPF | 0.679869 | 3 | 0 | 3 |
| CHRNG | RASGRP2 | 0.675077 | 3 | 0 | 3 |
| CHRNG | GABRB2 | 0.66684 | 3 | 0 | 3 |
| CHRNG | MAGEC1 | 0.661366 | 3 | 0 | 3 |
| CHRNG | CAPN11 | 0.659623 | 4 | 0 | 3 |
| CHRNG | UBE2D4 | 0.657503 | 3 | 0 | 3 |
| CHRNG | WDR60 | 0.656038 | 3 | 0 | 3 |
| CHRNG | CTSE | 0.655688 | 4 | 0 | 4 |
| CHRNG | LAT2 | 0.6556 | 3 | 0 | 3 |
| CHRNG | C4BPA | 0.654753 | 5 | 0 | 5 |
| CHRNG | LINC01260 | 0.65447 | 5 | 0 | 5 |
| CHRNG | NPTXR | 0.653287 | 8 | 0 | 8 |
| CHRNG | SLC6A11 | 0.647376 | 4 | 0 | 3 |
| CHRNG | MAP1A | 0.644027 | 3 | 0 | 3 |
| CHRNG | SSUH2 | 0.643173 | 4 | 0 | 3 |
For details and further investigation, click here
