| Full name: cytoskeleton associated protein 4 | Alias Symbol: P63|CLIMP-63|ERGIC-63 | ||
| Type: protein-coding gene | Cytoband: 12q23.3 | ||
| Entrez ID: 10970 | HGNC ID: HGNC:16991 | Ensembl Gene: ENSG00000136026 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of CKAP4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CKAP4 | 10970 | 200999_s_at | 0.3431 | 0.4519 | |
| GSE20347 | CKAP4 | 10970 | 200999_s_at | -0.4452 | 0.0018 | |
| GSE23400 | CKAP4 | 10970 | 200999_s_at | 0.1163 | 0.2209 | |
| GSE26886 | CKAP4 | 10970 | 200999_s_at | -0.2009 | 0.2968 | |
| GSE29001 | CKAP4 | 10970 | 200999_s_at | -0.1280 | 0.6930 | |
| GSE38129 | CKAP4 | 10970 | 200999_s_at | 0.1059 | 0.5658 | |
| GSE45670 | CKAP4 | 10970 | 200999_s_at | 0.1947 | 0.1757 | |
| GSE63941 | CKAP4 | 10970 | 200999_s_at | -3.2529 | 0.0005 | |
| GSE77861 | CKAP4 | 10970 | 200999_s_at | 0.0755 | 0.7612 | |
| GSE97050 | CKAP4 | 10970 | A_23_P48056 | 0.6288 | 0.1927 | |
| SRP007169 | CKAP4 | 10970 | RNAseq | -1.5721 | 0.0001 | |
| SRP008496 | CKAP4 | 10970 | RNAseq | -1.2012 | 0.0000 | |
| SRP064894 | CKAP4 | 10970 | RNAseq | 0.2402 | 0.1537 | |
| SRP133303 | CKAP4 | 10970 | RNAseq | 0.2947 | 0.1037 | |
| SRP159526 | CKAP4 | 10970 | RNAseq | 0.1851 | 0.4910 | |
| SRP193095 | CKAP4 | 10970 | RNAseq | -0.1956 | 0.2003 | |
| SRP219564 | CKAP4 | 10970 | RNAseq | 0.1066 | 0.8050 | |
| TCGA | CKAP4 | 10970 | RNAseq | 0.0850 | 0.0740 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by CKAP4 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of CKAP4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CKAP4 | 10970 | 5 | 3 | 22 | |
| GSE20123 | CKAP4 | 10970 | 5 | 3 | 22 | |
| GSE43470 | CKAP4 | 10970 | 2 | 1 | 40 | |
| GSE46452 | CKAP4 | 10970 | 9 | 1 | 49 | |
| GSE47630 | CKAP4 | 10970 | 9 | 1 | 30 | |
| GSE54993 | CKAP4 | 10970 | 0 | 5 | 65 | |
| GSE54994 | CKAP4 | 10970 | 4 | 2 | 47 | |
| GSE60625 | CKAP4 | 10970 | 0 | 0 | 11 | |
| GSE74703 | CKAP4 | 10970 | 2 | 0 | 34 | |
| GSE74704 | CKAP4 | 10970 | 2 | 2 | 16 | |
| TCGA | CKAP4 | 10970 | 21 | 9 | 66 |
Total number of gains: 59; Total number of losses: 27; Total Number of normals: 402.
Somatic mutations of CKAP4:
Generating mutation plots.
Highly correlated genes for CKAP4:
Showing top 20/108 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CKAP4 | OSTC | 0.725644 | 3 | 0 | 3 |
| CKAP4 | ATP6V1A | 0.693225 | 3 | 0 | 3 |
| CKAP4 | CDK2AP1 | 0.681314 | 3 | 0 | 3 |
| CKAP4 | IKBIP | 0.670582 | 3 | 0 | 3 |
| CKAP4 | LACTB | 0.669304 | 4 | 0 | 3 |
| CKAP4 | NAA40 | 0.655612 | 3 | 0 | 3 |
| CKAP4 | LOX | 0.649051 | 4 | 0 | 3 |
| CKAP4 | PRKAR1A | 0.634678 | 3 | 0 | 3 |
| CKAP4 | CTSB | 0.634436 | 4 | 0 | 4 |
| CKAP4 | DOCK10 | 0.634085 | 3 | 0 | 3 |
| CKAP4 | ELMOD2 | 0.632183 | 3 | 0 | 3 |
| CKAP4 | VSIG1 | 0.627173 | 3 | 0 | 3 |
| CKAP4 | GORASP2 | 0.62565 | 3 | 0 | 3 |
| CKAP4 | MCTP2 | 0.623396 | 4 | 0 | 4 |
| CKAP4 | SLC22A23 | 0.620985 | 5 | 0 | 4 |
| CKAP4 | COPB2 | 0.618723 | 5 | 0 | 3 |
| CKAP4 | NAT1 | 0.618033 | 4 | 0 | 3 |
| CKAP4 | SUSD1 | 0.614666 | 4 | 0 | 3 |
| CKAP4 | STK35 | 0.611764 | 4 | 0 | 3 |
| CKAP4 | SSR1 | 0.608818 | 5 | 0 | 3 |
For details and further investigation, click here
