| Full name: signal sequence receptor subunit 1 | Alias Symbol: TRAPA | ||
| Type: protein-coding gene | Cytoband: 6p24.3 | ||
| Entrez ID: 6745 | HGNC ID: HGNC:11323 | Ensembl Gene: ENSG00000124783 | OMIM ID: 600868 |
| Drug and gene relationship at DGIdb | |||
Expression of SSR1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SSR1 | 6745 | 200891_s_at | 0.6910 | 0.1307 | |
| GSE20347 | SSR1 | 6745 | 200891_s_at | 0.0851 | 0.5372 | |
| GSE23400 | SSR1 | 6745 | 200891_s_at | 0.3941 | 0.0000 | |
| GSE26886 | SSR1 | 6745 | 200891_s_at | -0.1011 | 0.5738 | |
| GSE29001 | SSR1 | 6745 | 200891_s_at | 0.1565 | 0.5858 | |
| GSE38129 | SSR1 | 6745 | 200891_s_at | 0.1620 | 0.2097 | |
| GSE45670 | SSR1 | 6745 | 200891_s_at | 0.4530 | 0.0001 | |
| GSE53622 | SSR1 | 6745 | 119905 | 0.2238 | 0.0000 | |
| GSE53624 | SSR1 | 6745 | 39296 | 0.1985 | 0.0001 | |
| GSE63941 | SSR1 | 6745 | 200891_s_at | -1.0317 | 0.0154 | |
| GSE77861 | SSR1 | 6745 | 200891_s_at | -0.0933 | 0.7425 | |
| GSE97050 | SSR1 | 6745 | A_33_P3396692 | 0.5354 | 0.1372 | |
| SRP007169 | SSR1 | 6745 | RNAseq | -0.1450 | 0.7014 | |
| SRP008496 | SSR1 | 6745 | RNAseq | -0.0436 | 0.8196 | |
| SRP064894 | SSR1 | 6745 | RNAseq | 0.5919 | 0.0001 | |
| SRP133303 | SSR1 | 6745 | RNAseq | 0.2860 | 0.1637 | |
| SRP159526 | SSR1 | 6745 | RNAseq | 0.4563 | 0.0101 | |
| SRP193095 | SSR1 | 6745 | RNAseq | -0.0237 | 0.8539 | |
| SRP219564 | SSR1 | 6745 | RNAseq | 0.4448 | 0.2132 | |
| TCGA | SSR1 | 6745 | RNAseq | 0.0088 | 0.8241 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by SSR1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SSR1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SSR1 | 6745 | 4 | 5 | 21 | |
| GSE20123 | SSR1 | 6745 | 4 | 5 | 21 | |
| GSE43470 | SSR1 | 6745 | 10 | 2 | 31 | |
| GSE46452 | SSR1 | 6745 | 1 | 10 | 48 | |
| GSE47630 | SSR1 | 6745 | 7 | 8 | 25 | |
| GSE54993 | SSR1 | 6745 | 1 | 1 | 68 | |
| GSE54994 | SSR1 | 6745 | 10 | 3 | 40 | |
| GSE60625 | SSR1 | 6745 | 0 | 1 | 10 | |
| GSE74703 | SSR1 | 6745 | 8 | 2 | 26 | |
| GSE74704 | SSR1 | 6745 | 2 | 2 | 16 | |
| TCGA | SSR1 | 6745 | 15 | 29 | 52 |
Total number of gains: 62; Total number of losses: 68; Total Number of normals: 358.
Somatic mutations of SSR1:
Generating mutation plots.
Highly correlated genes for SSR1:
Showing top 20/370 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SSR1 | LYSMD3 | 0.741178 | 3 | 0 | 3 |
| SSR1 | PAPSS2 | 0.732213 | 3 | 0 | 3 |
| SSR1 | MTCH2 | 0.727747 | 3 | 0 | 3 |
| SSR1 | LCMT1 | 0.713453 | 3 | 0 | 3 |
| SSR1 | TP53RK | 0.709829 | 3 | 0 | 3 |
| SSR1 | KLHL8 | 0.699027 | 3 | 0 | 3 |
| SSR1 | MMP15 | 0.693879 | 3 | 0 | 3 |
| SSR1 | ARID1B | 0.679188 | 3 | 0 | 3 |
| SSR1 | OSTC | 0.678362 | 5 | 0 | 4 |
| SSR1 | KBTBD6 | 0.678101 | 4 | 0 | 4 |
| SSR1 | TPM3 | 0.676544 | 5 | 0 | 3 |
| SSR1 | WDR4 | 0.670571 | 4 | 0 | 3 |
| SSR1 | SDHC | 0.668406 | 4 | 0 | 4 |
| SSR1 | DDX28 | 0.665446 | 4 | 0 | 3 |
| SSR1 | DTNBP1 | 0.664308 | 3 | 0 | 3 |
| SSR1 | PRRC2C | 0.664148 | 6 | 0 | 5 |
| SSR1 | NAT1 | 0.662379 | 4 | 0 | 3 |
| SSR1 | NDUFB3 | 0.661312 | 3 | 0 | 3 |
| SSR1 | LARS2 | 0.657106 | 4 | 0 | 3 |
| SSR1 | TCERG1 | 0.652886 | 4 | 0 | 4 |
For details and further investigation, click here
