| Full name: IKBKB interacting protein | Alias Symbol: FLJ31051|IKIP | ||
| Type: protein-coding gene | Cytoband: 12q23.1 | ||
| Entrez ID: 121457 | HGNC ID: HGNC:26430 | Ensembl Gene: ENSG00000166130 | OMIM ID: 609861 |
| Drug and gene relationship at DGIdb | |||
Expression of IKBIP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IKBIP | 121457 | 227295_at | 0.5030 | 0.5130 | |
| GSE26886 | IKBIP | 121457 | 236249_at | 1.7114 | 0.0000 | |
| GSE45670 | IKBIP | 121457 | 227295_at | 0.3193 | 0.4748 | |
| GSE53622 | IKBIP | 121457 | 97603 | 1.1456 | 0.0000 | |
| GSE53624 | IKBIP | 121457 | 97603 | 1.2546 | 0.0000 | |
| GSE63941 | IKBIP | 121457 | 227295_at | -2.0301 | 0.0533 | |
| GSE77861 | IKBIP | 121457 | 236249_at | 0.3645 | 0.0073 | |
| GSE97050 | IKBIP | 121457 | A_23_P53467 | 0.9738 | 0.0844 | |
| SRP007169 | IKBIP | 121457 | RNAseq | 2.3111 | 0.0000 | |
| SRP008496 | IKBIP | 121457 | RNAseq | 2.3744 | 0.0000 | |
| SRP064894 | IKBIP | 121457 | RNAseq | 1.5950 | 0.0000 | |
| SRP133303 | IKBIP | 121457 | RNAseq | 1.4208 | 0.0000 | |
| SRP159526 | IKBIP | 121457 | RNAseq | 0.8851 | 0.0016 | |
| SRP193095 | IKBIP | 121457 | RNAseq | 1.2690 | 0.0000 | |
| SRP219564 | IKBIP | 121457 | RNAseq | 0.9725 | 0.0491 | |
| TCGA | IKBIP | 121457 | RNAseq | 0.5576 | 0.0000 |
Upregulated datasets: 8; Downregulated datasets: 0.
Survival by IKBIP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IKBIP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IKBIP | 121457 | 2 | 3 | 25 | |
| GSE20123 | IKBIP | 121457 | 2 | 3 | 25 | |
| GSE43470 | IKBIP | 121457 | 2 | 0 | 41 | |
| GSE46452 | IKBIP | 121457 | 9 | 1 | 49 | |
| GSE47630 | IKBIP | 121457 | 9 | 2 | 29 | |
| GSE54993 | IKBIP | 121457 | 0 | 5 | 65 | |
| GSE54994 | IKBIP | 121457 | 4 | 2 | 47 | |
| GSE60625 | IKBIP | 121457 | 0 | 0 | 11 | |
| GSE74703 | IKBIP | 121457 | 2 | 0 | 34 | |
| GSE74704 | IKBIP | 121457 | 1 | 2 | 17 | |
| TCGA | IKBIP | 121457 | 17 | 9 | 70 |
Total number of gains: 48; Total number of losses: 27; Total Number of normals: 413.
Somatic mutations of IKBIP:
Generating mutation plots.
Highly correlated genes for IKBIP:
Showing top 20/1607 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IKBIP | LTBR | 0.840914 | 3 | 0 | 3 |
| IKBIP | ALKBH6 | 0.82356 | 3 | 0 | 3 |
| IKBIP | HAS3 | 0.815832 | 3 | 0 | 3 |
| IKBIP | TMEM132A | 0.811617 | 3 | 0 | 3 |
| IKBIP | SPON2 | 0.797882 | 3 | 0 | 3 |
| IKBIP | GNA12 | 0.76788 | 6 | 0 | 6 |
| IKBIP | MFAP2 | 0.766483 | 6 | 0 | 6 |
| IKBIP | LRCH3 | 0.765715 | 3 | 0 | 3 |
| IKBIP | WDR81 | 0.765615 | 3 | 0 | 3 |
| IKBIP | FCGR3A | 0.763337 | 3 | 0 | 3 |
| IKBIP | OSBPL6 | 0.761759 | 3 | 0 | 3 |
| IKBIP | GAS2L1 | 0.760549 | 4 | 0 | 4 |
| IKBIP | ZBED1 | 0.760123 | 3 | 0 | 3 |
| IKBIP | OSR2 | 0.757295 | 3 | 0 | 3 |
| IKBIP | WIZ | 0.749519 | 3 | 0 | 3 |
| IKBIP | MAGOHB | 0.74751 | 3 | 0 | 3 |
| IKBIP | PLEK2 | 0.746938 | 6 | 0 | 6 |
| IKBIP | BRIX1 | 0.744996 | 5 | 0 | 5 |
| IKBIP | CHST11 | 0.744035 | 6 | 0 | 6 |
| IKBIP | LPCAT1 | 0.739563 | 7 | 0 | 7 |
For details and further investigation, click here
