| Full name: coatomer protein complex subunit beta 2 | Alias Symbol: beta'-COP|betaprime-COP | ||
| Type: protein-coding gene | Cytoband: 3q23 | ||
| Entrez ID: 9276 | HGNC ID: HGNC:2232 | Ensembl Gene: ENSG00000184432 | OMIM ID: 606990 |
| Drug and gene relationship at DGIdb | |||
Expression of COPB2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | COPB2 | 9276 | 201098_at | 0.3819 | 0.3050 | |
| GSE20347 | COPB2 | 9276 | 201098_at | 0.2194 | 0.0870 | |
| GSE23400 | COPB2 | 9276 | 201098_at | 0.3768 | 0.0000 | |
| GSE26886 | COPB2 | 9276 | 201098_at | 0.1174 | 0.5479 | |
| GSE29001 | COPB2 | 9276 | 201098_at | 0.0134 | 0.9785 | |
| GSE38129 | COPB2 | 9276 | 201098_at | 0.3204 | 0.0043 | |
| GSE45670 | COPB2 | 9276 | 201098_at | 0.3708 | 0.0017 | |
| GSE53622 | COPB2 | 9276 | 51483 | 0.3593 | 0.0000 | |
| GSE53624 | COPB2 | 9276 | 51483 | 0.3381 | 0.0000 | |
| GSE63941 | COPB2 | 9276 | 201098_at | -0.3065 | 0.4445 | |
| GSE77861 | COPB2 | 9276 | 201098_at | 0.1560 | 0.6282 | |
| GSE97050 | COPB2 | 9276 | A_23_P91891 | 0.2832 | 0.2483 | |
| SRP007169 | COPB2 | 9276 | RNAseq | -0.1124 | 0.7365 | |
| SRP008496 | COPB2 | 9276 | RNAseq | 0.0299 | 0.8939 | |
| SRP064894 | COPB2 | 9276 | RNAseq | 0.0257 | 0.8934 | |
| SRP133303 | COPB2 | 9276 | RNAseq | 0.4204 | 0.0009 | |
| SRP159526 | COPB2 | 9276 | RNAseq | 0.4999 | 0.1330 | |
| SRP193095 | COPB2 | 9276 | RNAseq | 0.0505 | 0.7059 | |
| SRP219564 | COPB2 | 9276 | RNAseq | -0.0162 | 0.9631 | |
| TCGA | COPB2 | 9276 | RNAseq | 0.0632 | 0.1463 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by COPB2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of COPB2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | COPB2 | 9276 | 18 | 0 | 12 | |
| GSE20123 | COPB2 | 9276 | 18 | 0 | 12 | |
| GSE43470 | COPB2 | 9276 | 22 | 0 | 21 | |
| GSE46452 | COPB2 | 9276 | 15 | 4 | 40 | |
| GSE47630 | COPB2 | 9276 | 18 | 3 | 19 | |
| GSE54993 | COPB2 | 9276 | 2 | 8 | 60 | |
| GSE54994 | COPB2 | 9276 | 32 | 1 | 20 | |
| GSE60625 | COPB2 | 9276 | 0 | 6 | 5 | |
| GSE74703 | COPB2 | 9276 | 19 | 0 | 17 | |
| GSE74704 | COPB2 | 9276 | 12 | 0 | 8 | |
| TCGA | COPB2 | 9276 | 61 | 4 | 31 |
Total number of gains: 217; Total number of losses: 26; Total Number of normals: 245.
Somatic mutations of COPB2:
Generating mutation plots.
Highly correlated genes for COPB2:
Showing top 20/648 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| COPB2 | RPS6KB1 | 0.709536 | 3 | 0 | 3 |
| COPB2 | IL10RB | 0.690738 | 3 | 0 | 3 |
| COPB2 | HAS3 | 0.689487 | 3 | 0 | 3 |
| COPB2 | COPG1 | 0.679081 | 8 | 0 | 7 |
| COPB2 | NCAPH | 0.676301 | 4 | 0 | 4 |
| COPB2 | UMPS | 0.674858 | 9 | 0 | 8 |
| COPB2 | LIPT1 | 0.674273 | 3 | 0 | 3 |
| COPB2 | RAD21 | 0.671209 | 3 | 0 | 3 |
| COPB2 | PDCD10 | 0.665644 | 12 | 0 | 9 |
| COPB2 | NDUFB4 | 0.662647 | 8 | 0 | 8 |
| COPB2 | MON2 | 0.657576 | 4 | 0 | 3 |
| COPB2 | ARHGEF18 | 0.64741 | 4 | 0 | 4 |
| COPB2 | STEAP1B | 0.64432 | 4 | 0 | 3 |
| COPB2 | FAHD1 | 0.642353 | 3 | 0 | 3 |
| COPB2 | HOXA10 | 0.639878 | 3 | 0 | 3 |
| COPB2 | CDCA2 | 0.638796 | 4 | 0 | 3 |
| COPB2 | ATP6V1G1 | 0.63757 | 3 | 0 | 3 |
| COPB2 | RCC2 | 0.637433 | 4 | 0 | 4 |
| COPB2 | ZBTB9 | 0.635844 | 4 | 0 | 3 |
| COPB2 | MRPL3 | 0.63385 | 11 | 0 | 9 |
For details and further investigation, click here
