| Full name: multiple C2 and transmembrane domain containing 2 | Alias Symbol: FLJ11175|FLJ33303 | ||
| Type: protein-coding gene | Cytoband: 15q26.2 | ||
| Entrez ID: 55784 | HGNC ID: HGNC:25636 | Ensembl Gene: ENSG00000140563 | OMIM ID: 616297 |
| Drug and gene relationship at DGIdb | |||
Expression of MCTP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MCTP2 | 55784 | 220603_s_at | 0.5506 | 0.4974 | |
| GSE20347 | MCTP2 | 55784 | 220603_s_at | 0.3177 | 0.0591 | |
| GSE23400 | MCTP2 | 55784 | 220603_s_at | 0.1318 | 0.0076 | |
| GSE26886 | MCTP2 | 55784 | 220603_s_at | 0.1509 | 0.5213 | |
| GSE29001 | MCTP2 | 55784 | 220603_s_at | 0.6016 | 0.0623 | |
| GSE38129 | MCTP2 | 55784 | 220603_s_at | 0.6685 | 0.0001 | |
| GSE45670 | MCTP2 | 55784 | 220603_s_at | 0.5175 | 0.0203 | |
| GSE53622 | MCTP2 | 55784 | 23115 | 0.5973 | 0.0000 | |
| GSE53624 | MCTP2 | 55784 | 23115 | 0.3409 | 0.0001 | |
| GSE63941 | MCTP2 | 55784 | 220603_s_at | -0.8494 | 0.3163 | |
| GSE77861 | MCTP2 | 55784 | 229021_at | 0.0263 | 0.8771 | |
| GSE97050 | MCTP2 | 55784 | A_24_P244944 | 0.5232 | 0.3704 | |
| SRP007169 | MCTP2 | 55784 | RNAseq | -0.2972 | 0.6368 | |
| SRP008496 | MCTP2 | 55784 | RNAseq | -0.2775 | 0.5291 | |
| SRP064894 | MCTP2 | 55784 | RNAseq | 0.0437 | 0.8709 | |
| SRP133303 | MCTP2 | 55784 | RNAseq | 0.2194 | 0.2419 | |
| SRP159526 | MCTP2 | 55784 | RNAseq | 0.2152 | 0.4255 | |
| SRP193095 | MCTP2 | 55784 | RNAseq | 0.3855 | 0.0002 | |
| SRP219564 | MCTP2 | 55784 | RNAseq | 0.8199 | 0.2362 | |
| TCGA | MCTP2 | 55784 | RNAseq | 0.2744 | 0.0017 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MCTP2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MCTP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MCTP2 | 55784 | 6 | 2 | 22 | |
| GSE20123 | MCTP2 | 55784 | 7 | 2 | 21 | |
| GSE43470 | MCTP2 | 55784 | 4 | 4 | 35 | |
| GSE46452 | MCTP2 | 55784 | 3 | 7 | 49 | |
| GSE47630 | MCTP2 | 55784 | 9 | 10 | 21 | |
| GSE54993 | MCTP2 | 55784 | 4 | 6 | 60 | |
| GSE54994 | MCTP2 | 55784 | 9 | 7 | 37 | |
| GSE60625 | MCTP2 | 55784 | 4 | 0 | 7 | |
| GSE74703 | MCTP2 | 55784 | 3 | 3 | 30 | |
| GSE74704 | MCTP2 | 55784 | 3 | 3 | 14 | |
| TCGA | MCTP2 | 55784 | 18 | 12 | 66 |
Total number of gains: 70; Total number of losses: 56; Total Number of normals: 362.
Somatic mutations of MCTP2:
Generating mutation plots.
Highly correlated genes for MCTP2:
Showing top 20/530 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MCTP2 | PPP1CA | 0.786647 | 3 | 0 | 3 |
| MCTP2 | CDYL2 | 0.731471 | 3 | 0 | 3 |
| MCTP2 | TMEM60 | 0.722619 | 3 | 0 | 3 |
| MCTP2 | SORD | 0.720875 | 4 | 0 | 3 |
| MCTP2 | LEO1 | 0.719417 | 3 | 0 | 3 |
| MCTP2 | LRRC59 | 0.714986 | 5 | 0 | 4 |
| MCTP2 | PPP4C | 0.690284 | 3 | 0 | 3 |
| MCTP2 | FAM83B | 0.683486 | 4 | 0 | 4 |
| MCTP2 | DNAJC7 | 0.677251 | 3 | 0 | 3 |
| MCTP2 | SLC30A7 | 0.675584 | 4 | 0 | 3 |
| MCTP2 | F2RL1 | 0.674806 | 4 | 0 | 4 |
| MCTP2 | PPIF | 0.674626 | 3 | 0 | 3 |
| MCTP2 | RNF149 | 0.670787 | 3 | 0 | 3 |
| MCTP2 | EIF2S2 | 0.670626 | 4 | 0 | 4 |
| MCTP2 | PLEKHA2 | 0.667725 | 4 | 0 | 3 |
| MCTP2 | CDCA2 | 0.663718 | 3 | 0 | 3 |
| MCTP2 | PKN3 | 0.661269 | 3 | 0 | 3 |
| MCTP2 | SESN3 | 0.656907 | 4 | 0 | 3 |
| MCTP2 | AAGAB | 0.654542 | 6 | 0 | 4 |
| MCTP2 | GSR | 0.652927 | 4 | 0 | 3 |
For details and further investigation, click here
