| Full name: Rap1 GTPase-GDP dissociation stimulator 1 | Alias Symbol: SmgGDS | ||
| Type: protein-coding gene | Cytoband: 4q23 | ||
| Entrez ID: 5910 | HGNC ID: HGNC:9859 | Ensembl Gene: ENSG00000138698 | OMIM ID: 179502 |
| Drug and gene relationship at DGIdb | |||
Expression of RAP1GDS1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RAP1GDS1 | 5910 | 209444_at | 0.2478 | 0.6178 | |
| GSE20347 | RAP1GDS1 | 5910 | 209444_at | -0.8615 | 0.0000 | |
| GSE23400 | RAP1GDS1 | 5910 | 209444_at | -0.4068 | 0.0003 | |
| GSE26886 | RAP1GDS1 | 5910 | 209444_at | -0.4638 | 0.0282 | |
| GSE29001 | RAP1GDS1 | 5910 | 209444_at | -0.7629 | 0.0504 | |
| GSE38129 | RAP1GDS1 | 5910 | 209444_at | -0.4615 | 0.0130 | |
| GSE45670 | RAP1GDS1 | 5910 | 209444_at | -0.3183 | 0.0501 | |
| GSE53622 | RAP1GDS1 | 5910 | 31619 | -0.1967 | 0.0055 | |
| GSE53624 | RAP1GDS1 | 5910 | 31619 | -0.4821 | 0.0000 | |
| GSE63941 | RAP1GDS1 | 5910 | 209444_at | -0.9991 | 0.0427 | |
| GSE77861 | RAP1GDS1 | 5910 | 209444_at | -0.7122 | 0.0126 | |
| GSE97050 | RAP1GDS1 | 5910 | A_33_P3215123 | 0.1066 | 0.7784 | |
| SRP007169 | RAP1GDS1 | 5910 | RNAseq | -1.5050 | 0.0010 | |
| SRP008496 | RAP1GDS1 | 5910 | RNAseq | -1.3672 | 0.0000 | |
| SRP064894 | RAP1GDS1 | 5910 | RNAseq | -0.6104 | 0.0000 | |
| SRP133303 | RAP1GDS1 | 5910 | RNAseq | -0.0451 | 0.8355 | |
| SRP159526 | RAP1GDS1 | 5910 | RNAseq | -0.6942 | 0.0198 | |
| SRP193095 | RAP1GDS1 | 5910 | RNAseq | -0.4580 | 0.0021 | |
| SRP219564 | RAP1GDS1 | 5910 | RNAseq | -0.5653 | 0.0574 | |
| TCGA | RAP1GDS1 | 5910 | RNAseq | 0.0021 | 0.9706 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by RAP1GDS1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RAP1GDS1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RAP1GDS1 | 5910 | 0 | 12 | 18 | |
| GSE20123 | RAP1GDS1 | 5910 | 0 | 12 | 18 | |
| GSE43470 | RAP1GDS1 | 5910 | 0 | 15 | 28 | |
| GSE46452 | RAP1GDS1 | 5910 | 1 | 36 | 22 | |
| GSE47630 | RAP1GDS1 | 5910 | 0 | 20 | 20 | |
| GSE54993 | RAP1GDS1 | 5910 | 9 | 0 | 61 | |
| GSE54994 | RAP1GDS1 | 5910 | 1 | 11 | 41 | |
| GSE60625 | RAP1GDS1 | 5910 | 0 | 3 | 8 | |
| GSE74703 | RAP1GDS1 | 5910 | 0 | 13 | 23 | |
| GSE74704 | RAP1GDS1 | 5910 | 0 | 6 | 14 | |
| TCGA | RAP1GDS1 | 5910 | 8 | 41 | 47 |
Total number of gains: 19; Total number of losses: 169; Total Number of normals: 300.
Somatic mutations of RAP1GDS1:
Generating mutation plots.
Highly correlated genes for RAP1GDS1:
Showing top 20/888 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RAP1GDS1 | KDM2B | 0.900137 | 3 | 0 | 3 |
| RAP1GDS1 | ATG3 | 0.784263 | 3 | 0 | 3 |
| RAP1GDS1 | COG3 | 0.76304 | 3 | 0 | 3 |
| RAP1GDS1 | GORASP2 | 0.758419 | 3 | 0 | 3 |
| RAP1GDS1 | TM2D2 | 0.753817 | 3 | 0 | 3 |
| RAP1GDS1 | ZNF578 | 0.750462 | 3 | 0 | 3 |
| RAP1GDS1 | ECD | 0.7409 | 3 | 0 | 3 |
| RAP1GDS1 | BRWD1 | 0.738798 | 3 | 0 | 3 |
| RAP1GDS1 | SRP9 | 0.73664 | 3 | 0 | 3 |
| RAP1GDS1 | SEC24D | 0.726323 | 3 | 0 | 3 |
| RAP1GDS1 | ARL16 | 0.721295 | 3 | 0 | 3 |
| RAP1GDS1 | ZNF416 | 0.720509 | 5 | 0 | 5 |
| RAP1GDS1 | EPG5 | 0.720171 | 5 | 0 | 5 |
| RAP1GDS1 | TTC37 | 0.71813 | 5 | 0 | 4 |
| RAP1GDS1 | CLDN2 | 0.717224 | 3 | 0 | 3 |
| RAP1GDS1 | NUP54 | 0.709047 | 3 | 0 | 3 |
| RAP1GDS1 | SETD4 | 0.708398 | 3 | 0 | 3 |
| RAP1GDS1 | ZNF557 | 0.701678 | 4 | 0 | 4 |
| RAP1GDS1 | LRP11 | 0.700888 | 4 | 0 | 3 |
| RAP1GDS1 | MMAA | 0.697694 | 4 | 0 | 4 |
For details and further investigation, click here
