| Full name: BTB domain and CNC homolog 2 | Alias Symbol: BTBD25 | ||
| Type: protein-coding gene | Cytoband: 6q15 | ||
| Entrez ID: 60468 | HGNC ID: HGNC:14078 | Ensembl Gene: ENSG00000112182 | OMIM ID: 605394 |
| Drug and gene relationship at DGIdb | |||
Expression of BACH2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BACH2 | 60468 | 227173_s_at | 0.0380 | 0.9454 | |
| GSE20347 | BACH2 | 60468 | 221234_s_at | 0.3799 | 0.1306 | |
| GSE23400 | BACH2 | 60468 | 221234_s_at | 0.1790 | 0.0223 | |
| GSE26886 | BACH2 | 60468 | 227173_s_at | 0.4843 | 0.0018 | |
| GSE29001 | BACH2 | 60468 | 221234_s_at | 0.2450 | 0.6038 | |
| GSE38129 | BACH2 | 60468 | 221234_s_at | 0.4357 | 0.1050 | |
| GSE45670 | BACH2 | 60468 | 227173_s_at | 0.0017 | 0.9924 | |
| GSE53622 | BACH2 | 60468 | 57220 | 0.5867 | 0.0002 | |
| GSE53624 | BACH2 | 60468 | 35238 | 0.3800 | 0.0124 | |
| GSE63941 | BACH2 | 60468 | 227173_s_at | 0.1916 | 0.5417 | |
| GSE77861 | BACH2 | 60468 | 227173_s_at | -0.0779 | 0.4060 | |
| GSE97050 | BACH2 | 60468 | A_33_P3302916 | 0.3768 | 0.2433 | |
| SRP007169 | BACH2 | 60468 | RNAseq | 2.5013 | 0.0008 | |
| SRP008496 | BACH2 | 60468 | RNAseq | 2.1709 | 0.0001 | |
| SRP064894 | BACH2 | 60468 | RNAseq | 0.5802 | 0.0608 | |
| SRP133303 | BACH2 | 60468 | RNAseq | 0.1473 | 0.5044 | |
| SRP159526 | BACH2 | 60468 | RNAseq | 0.0418 | 0.9490 | |
| SRP193095 | BACH2 | 60468 | RNAseq | 0.5574 | 0.0158 | |
| SRP219564 | BACH2 | 60468 | RNAseq | 0.1653 | 0.7112 | |
| TCGA | BACH2 | 60468 | RNAseq | 0.0769 | 0.6206 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by BACH2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of BACH2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BACH2 | 60468 | 1 | 4 | 25 | |
| GSE20123 | BACH2 | 60468 | 1 | 3 | 26 | |
| GSE43470 | BACH2 | 60468 | 2 | 1 | 40 | |
| GSE46452 | BACH2 | 60468 | 2 | 11 | 46 | |
| GSE47630 | BACH2 | 60468 | 8 | 6 | 26 | |
| GSE54993 | BACH2 | 60468 | 3 | 2 | 65 | |
| GSE54994 | BACH2 | 60468 | 8 | 10 | 35 | |
| GSE60625 | BACH2 | 60468 | 0 | 1 | 10 | |
| GSE74703 | BACH2 | 60468 | 2 | 1 | 33 | |
| GSE74704 | BACH2 | 60468 | 0 | 2 | 18 | |
| TCGA | BACH2 | 60468 | 7 | 21 | 68 |
Total number of gains: 34; Total number of losses: 62; Total Number of normals: 392.
Somatic mutations of BACH2:
Generating mutation plots.
Highly correlated genes for BACH2:
Showing top 20/365 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BACH2 | CXCR5 | 0.75187 | 3 | 0 | 3 |
| BACH2 | DERL3 | 0.730432 | 3 | 0 | 3 |
| BACH2 | CLDN2 | 0.725908 | 3 | 0 | 3 |
| BACH2 | RNF113A | 0.725614 | 3 | 0 | 3 |
| BACH2 | TNFAIP8L2 | 0.716532 | 3 | 0 | 3 |
| BACH2 | UBA52 | 0.71025 | 3 | 0 | 3 |
| BACH2 | SEC11C | 0.702001 | 3 | 0 | 3 |
| BACH2 | DDX54 | 0.700665 | 3 | 0 | 3 |
| BACH2 | IRF8 | 0.694959 | 3 | 0 | 3 |
| BACH2 | RAB39B | 0.693577 | 4 | 0 | 4 |
| BACH2 | KCND1 | 0.690734 | 5 | 0 | 5 |
| BACH2 | SEC22C | 0.690642 | 3 | 0 | 3 |
| BACH2 | SLITRK6 | 0.687441 | 4 | 0 | 3 |
| BACH2 | MTAP | 0.685417 | 3 | 0 | 3 |
| BACH2 | DHX37 | 0.685377 | 3 | 0 | 3 |
| BACH2 | SLC39A10 | 0.684506 | 4 | 0 | 4 |
| BACH2 | SPRED1 | 0.682096 | 4 | 0 | 4 |
| BACH2 | ABHD2 | 0.681118 | 3 | 0 | 3 |
| BACH2 | AGT | 0.679126 | 4 | 0 | 3 |
| BACH2 | NFATC1 | 0.675055 | 8 | 0 | 7 |
For details and further investigation, click here
