| Full name: C-type lectin domain containing 10A | Alias Symbol: HML2|HML|CD301 | ||
| Type: protein-coding gene | Cytoband: 17p13.1 | ||
| Entrez ID: 10462 | HGNC ID: HGNC:16916 | Ensembl Gene: ENSG00000132514 | OMIM ID: 605999 |
| Drug and gene relationship at DGIdb | |||
Expression of CLEC10A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CLEC10A | 10462 | 206682_at | -0.7496 | 0.4361 | |
| GSE20347 | CLEC10A | 10462 | 206682_at | -0.5621 | 0.0000 | |
| GSE23400 | CLEC10A | 10462 | 206682_at | -0.3252 | 0.0000 | |
| GSE26886 | CLEC10A | 10462 | 206682_at | -1.6040 | 0.0000 | |
| GSE29001 | CLEC10A | 10462 | 206682_at | -0.8905 | 0.0003 | |
| GSE38129 | CLEC10A | 10462 | 206682_at | -0.6725 | 0.0000 | |
| GSE45670 | CLEC10A | 10462 | 206682_at | -0.9422 | 0.0003 | |
| GSE53622 | CLEC10A | 10462 | 29676 | -1.5409 | 0.0000 | |
| GSE53624 | CLEC10A | 10462 | 29676 | -1.5440 | 0.0000 | |
| GSE63941 | CLEC10A | 10462 | 206682_at | 0.2358 | 0.1547 | |
| GSE77861 | CLEC10A | 10462 | 206682_at | -0.4025 | 0.0785 | |
| GSE97050 | CLEC10A | 10462 | A_23_P141505 | 0.2700 | 0.5766 | |
| SRP007169 | CLEC10A | 10462 | RNAseq | -2.1912 | 0.0005 | |
| SRP064894 | CLEC10A | 10462 | RNAseq | -0.8720 | 0.0583 | |
| SRP133303 | CLEC10A | 10462 | RNAseq | -1.8244 | 0.0001 | |
| SRP159526 | CLEC10A | 10462 | RNAseq | -0.9831 | 0.5406 | |
| SRP193095 | CLEC10A | 10462 | RNAseq | -1.7746 | 0.0000 | |
| SRP219564 | CLEC10A | 10462 | RNAseq | -0.2849 | 0.7567 | |
| TCGA | CLEC10A | 10462 | RNAseq | -0.7312 | 0.0374 |
Upregulated datasets: 0; Downregulated datasets: 6.
Survival by CLEC10A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CLEC10A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CLEC10A | 10462 | 4 | 2 | 24 | |
| GSE20123 | CLEC10A | 10462 | 4 | 3 | 23 | |
| GSE43470 | CLEC10A | 10462 | 1 | 4 | 38 | |
| GSE46452 | CLEC10A | 10462 | 34 | 1 | 24 | |
| GSE47630 | CLEC10A | 10462 | 7 | 1 | 32 | |
| GSE54993 | CLEC10A | 10462 | 4 | 3 | 63 | |
| GSE54994 | CLEC10A | 10462 | 5 | 8 | 40 | |
| GSE60625 | CLEC10A | 10462 | 4 | 0 | 7 | |
| GSE74703 | CLEC10A | 10462 | 1 | 2 | 33 | |
| GSE74704 | CLEC10A | 10462 | 2 | 1 | 17 | |
| TCGA | CLEC10A | 10462 | 17 | 21 | 58 |
Total number of gains: 83; Total number of losses: 46; Total Number of normals: 359.
Somatic mutations of CLEC10A:
Generating mutation plots.
Highly correlated genes for CLEC10A:
Showing top 20/571 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CLEC10A | GIMAP7 | 0.777946 | 5 | 0 | 5 |
| CLEC10A | LINC00892 | 0.756006 | 4 | 0 | 4 |
| CLEC10A | CLDN5 | 0.704055 | 7 | 0 | 7 |
| CLEC10A | FGF23 | 0.691794 | 3 | 0 | 3 |
| CLEC10A | PLAC9 | 0.688245 | 5 | 0 | 5 |
| CLEC10A | CD1C | 0.677364 | 9 | 0 | 9 |
| CLEC10A | MPEG1 | 0.676507 | 6 | 0 | 5 |
| CLEC10A | ACKR1 | 0.675374 | 9 | 0 | 9 |
| CLEC10A | CMA1 | 0.675179 | 6 | 0 | 5 |
| CLEC10A | SUMF1 | 0.673224 | 3 | 0 | 3 |
| CLEC10A | CCL23 | 0.671044 | 4 | 0 | 3 |
| CLEC10A | CTSG | 0.670787 | 10 | 0 | 8 |
| CLEC10A | PTGDS | 0.668582 | 10 | 0 | 9 |
| CLEC10A | SLC9A9 | 0.656118 | 6 | 0 | 5 |
| CLEC10A | GIMAP6 | 0.654941 | 9 | 0 | 7 |
| CLEC10A | CFP | 0.653621 | 10 | 0 | 7 |
| CLEC10A | XCR1 | 0.651299 | 5 | 0 | 5 |
| CLEC10A | FAM107A | 0.650552 | 10 | 0 | 9 |
| CLEC10A | SPNS3 | 0.647456 | 5 | 0 | 4 |
| CLEC10A | THEMIS | 0.645664 | 5 | 0 | 4 |
For details and further investigation, click here
