| Full name: cathepsin G | Alias Symbol: CG | ||
| Type: protein-coding gene | Cytoband: 14q12 | ||
| Entrez ID: 1511 | HGNC ID: HGNC:2532 | Ensembl Gene: ENSG00000100448 | OMIM ID: 116830 |
| Drug and gene relationship at DGIdb | |||
Expression of CTSG:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CTSG | 1511 | 205653_at | -0.9702 | 0.1943 | |
| GSE20347 | CTSG | 1511 | 205653_at | -0.4466 | 0.0035 | |
| GSE23400 | CTSG | 1511 | 205653_at | -0.3364 | 0.0000 | |
| GSE26886 | CTSG | 1511 | 205653_at | -0.2008 | 0.2784 | |
| GSE29001 | CTSG | 1511 | 205653_at | -0.3918 | 0.0075 | |
| GSE38129 | CTSG | 1511 | 205653_at | -0.9937 | 0.0000 | |
| GSE45670 | CTSG | 1511 | 205653_at | -1.5741 | 0.0000 | |
| GSE53622 | CTSG | 1511 | 29512 | -1.3180 | 0.0000 | |
| GSE53624 | CTSG | 1511 | 29512 | -1.3209 | 0.0000 | |
| GSE63941 | CTSG | 1511 | 205653_at | 0.3777 | 0.0166 | |
| GSE77861 | CTSG | 1511 | 205653_at | -0.2575 | 0.0365 | |
| GSE97050 | CTSG | 1511 | A_23_P140384 | -0.0187 | 0.9711 | |
| SRP064894 | CTSG | 1511 | RNAseq | -1.5523 | 0.0037 | |
| SRP133303 | CTSG | 1511 | RNAseq | -2.4171 | 0.0003 | |
| SRP159526 | CTSG | 1511 | RNAseq | -0.7046 | 0.4908 | |
| SRP219564 | CTSG | 1511 | RNAseq | 0.2514 | 0.8449 | |
| TCGA | CTSG | 1511 | RNAseq | -1.8893 | 0.0007 |
Upregulated datasets: 0; Downregulated datasets: 6.
Survival by CTSG expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CTSG:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CTSG | 1511 | 8 | 3 | 19 | |
| GSE20123 | CTSG | 1511 | 8 | 3 | 19 | |
| GSE43470 | CTSG | 1511 | 8 | 2 | 33 | |
| GSE46452 | CTSG | 1511 | 16 | 2 | 41 | |
| GSE47630 | CTSG | 1511 | 11 | 10 | 19 | |
| GSE54993 | CTSG | 1511 | 3 | 11 | 56 | |
| GSE54994 | CTSG | 1511 | 18 | 5 | 30 | |
| GSE60625 | CTSG | 1511 | 0 | 2 | 9 | |
| GSE74703 | CTSG | 1511 | 7 | 2 | 27 | |
| GSE74704 | CTSG | 1511 | 3 | 2 | 15 | |
| TCGA | CTSG | 1511 | 27 | 12 | 57 |
Total number of gains: 109; Total number of losses: 54; Total Number of normals: 325.
Somatic mutations of CTSG:
Generating mutation plots.
Highly correlated genes for CTSG:
Showing top 20/417 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CTSG | GPR146 | 0.73137 | 3 | 0 | 3 |
| CTSG | ADORA1 | 0.701423 | 3 | 0 | 3 |
| CTSG | ABCA4 | 0.697161 | 4 | 0 | 4 |
| CTSG | SPATA31E1 | 0.693019 | 3 | 0 | 3 |
| CTSG | MAGEE2 | 0.69175 | 3 | 0 | 3 |
| CTSG | CCDC33 | 0.688727 | 3 | 0 | 3 |
| CTSG | GALR3 | 0.676509 | 6 | 0 | 5 |
| CTSG | TBX21 | 0.670864 | 3 | 0 | 3 |
| CTSG | CLEC10A | 0.670787 | 10 | 0 | 8 |
| CTSG | OR4D2 | 0.668109 | 4 | 0 | 4 |
| CTSG | HDC | 0.664657 | 11 | 0 | 8 |
| CTSG | DCLK1 | 0.657452 | 7 | 0 | 6 |
| CTSG | HTR3A | 0.653457 | 6 | 0 | 5 |
| CTSG | SCARA5 | 0.652947 | 5 | 0 | 4 |
| CTSG | PDE2A | 0.652354 | 10 | 0 | 9 |
| CTSG | STH | 0.651967 | 3 | 0 | 3 |
| CTSG | GATA2 | 0.651504 | 6 | 0 | 5 |
| CTSG | SLC8A3 | 0.650363 | 4 | 0 | 3 |
| CTSG | ACKR1 | 0.649574 | 9 | 0 | 8 |
| CTSG | FTHL17 | 0.64735 | 3 | 0 | 3 |
For details and further investigation, click here
