TMEM69

 

Full name: transmembrane protein 69 Alias Symbol: FLJ21029
Type: protein-coding gene Cytoband: 1p34.1
Entrez ID: 51249 HGNC ID: HGNC:28035 Ensembl Gene: ENSG00000159596 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of TMEM69:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TMEM69 51249 223335_at 0.3052 0.5714
GSE26886 TMEM69 51249 223335_at 0.3962 0.0411
GSE45670 TMEM69 51249 223335_at 0.2554 0.0158
GSE53622 TMEM69 51249 37729 0.3408 0.0000
GSE53624 TMEM69 51249 37729 0.5065 0.0000
GSE63941 TMEM69 51249 223335_at 0.8308 0.0174
GSE77861 TMEM69 51249 223335_at 0.0597 0.8754
GSE97050 TMEM69 51249 A_23_P104151 0.1338 0.6098
SRP007169 TMEM69 51249 RNAseq -0.2204 0.5923
SRP008496 TMEM69 51249 RNAseq -0.3559 0.1533
SRP064894 TMEM69 51249 RNAseq 0.2346 0.2049
SRP133303 TMEM69 51249 RNAseq 0.0833 0.5990
SRP159526 TMEM69 51249 RNAseq 0.0936 0.7226
SRP193095 TMEM69 51249 RNAseq 0.0171 0.8958
SRP219564 TMEM69 51249 RNAseq 0.1981 0.5883
TCGA TMEM69 51249 RNAseq 0.3052 0.0000

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by TMEM69 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of TMEM69:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TMEM69 51249 4 3 23
GSE20123 TMEM69 51249 4 2 24
GSE43470 TMEM69 51249 6 2 35
GSE46452 TMEM69 51249 2 1 56
GSE47630 TMEM69 51249 9 3 28
GSE54993 TMEM69 51249 0 1 69
GSE54994 TMEM69 51249 11 2 40
GSE60625 TMEM69 51249 0 0 11
GSE74703 TMEM69 51249 5 1 30
GSE74704 TMEM69 51249 2 0 18
TCGA TMEM69 51249 11 16 69

Total number of gains: 54; Total number of losses: 31; Total Number of normals: 403.  

 

Somatic mutations of TMEM69:

 

Generating mutation plots.

 

Highly correlated genes for TMEM69:

 

Showing top 20/613 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TMEM69PSMC60.878694303
TMEM69MAP4K50.875185303
TMEM69SMAD10.792369303
TMEM69STYX0.782062303
TMEM69GPBP1L10.772878403
TMEM69DYRK20.764192303
TMEM69TFIP110.763839303
TMEM69MYSM10.76373303
TMEM69NAA300.760545303
TMEM69TSPAN90.758936303
TMEM69MCMBP0.758915504
TMEM69UEVLD0.752961303
TMEM69KTI120.750524303
TMEM69EXOSC100.740106505
TMEM69NFKB20.739821303
TMEM69INTS120.731811403
TMEM69PDCD60.731281303
TMEM69CLP10.728982404
TMEM69MYOF0.728469303
TMEM69YTHDF20.722847403

For details and further investigation, click here