| Full name: claspin | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1p34.3 | ||
| Entrez ID: 63967 | HGNC ID: HGNC:19715 | Ensembl Gene: ENSG00000092853 | OMIM ID: 605434 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of CLSPN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CLSPN | 63967 | 243840_at | 0.6648 | 0.1673 | |
| GSE20347 | CLSPN | 63967 | 219621_at | 0.0761 | 0.2126 | |
| GSE23400 | CLSPN | 63967 | 219621_at | -0.0387 | 0.1854 | |
| GSE26886 | CLSPN | 63967 | 243840_at | 0.2654 | 0.0529 | |
| GSE29001 | CLSPN | 63967 | 219621_at | -0.0709 | 0.6067 | |
| GSE38129 | CLSPN | 63967 | 219621_at | 0.0759 | 0.1899 | |
| GSE45670 | CLSPN | 63967 | 243840_at | 0.8830 | 0.0000 | |
| GSE53622 | CLSPN | 63967 | 34914 | 1.9385 | 0.0000 | |
| GSE53624 | CLSPN | 63967 | 34914 | 2.2744 | 0.0000 | |
| GSE63941 | CLSPN | 63967 | 243840_at | 0.6245 | 0.2501 | |
| GSE77861 | CLSPN | 63967 | 243840_at | 0.2667 | 0.0070 | |
| GSE97050 | CLSPN | 63967 | A_23_P126212 | 0.7776 | 0.1983 | |
| SRP007169 | CLSPN | 63967 | RNAseq | 2.9514 | 0.0000 | |
| SRP008496 | CLSPN | 63967 | RNAseq | 1.7885 | 0.0002 | |
| SRP064894 | CLSPN | 63967 | RNAseq | 1.7510 | 0.0000 | |
| SRP133303 | CLSPN | 63967 | RNAseq | 1.5135 | 0.0000 | |
| SRP159526 | CLSPN | 63967 | RNAseq | 1.5987 | 0.0000 | |
| SRP193095 | CLSPN | 63967 | RNAseq | 1.0769 | 0.0000 | |
| SRP219564 | CLSPN | 63967 | RNAseq | 1.2207 | 0.0139 | |
| TCGA | CLSPN | 63967 | RNAseq | 1.2275 | 0.0000 |
Upregulated datasets: 10; Downregulated datasets: 0.
Survival by CLSPN expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CLSPN:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CLSPN | 63967 | 2 | 5 | 23 | |
| GSE20123 | CLSPN | 63967 | 2 | 4 | 24 | |
| GSE43470 | CLSPN | 63967 | 7 | 2 | 34 | |
| GSE46452 | CLSPN | 63967 | 4 | 1 | 54 | |
| GSE47630 | CLSPN | 63967 | 8 | 3 | 29 | |
| GSE54993 | CLSPN | 63967 | 1 | 1 | 68 | |
| GSE54994 | CLSPN | 63967 | 11 | 2 | 40 | |
| GSE60625 | CLSPN | 63967 | 0 | 0 | 11 | |
| GSE74703 | CLSPN | 63967 | 6 | 1 | 29 | |
| GSE74704 | CLSPN | 63967 | 1 | 0 | 19 | |
| TCGA | CLSPN | 63967 | 11 | 19 | 66 |
Total number of gains: 53; Total number of losses: 38; Total Number of normals: 397.
Somatic mutations of CLSPN:
Generating mutation plots.
Highly correlated genes for CLSPN:
Showing top 20/1533 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CLSPN | ANLN | 0.824236 | 6 | 0 | 6 |
| CLSPN | MGAT2 | 0.807364 | 3 | 0 | 3 |
| CLSPN | RAB11FIP5 | 0.802163 | 3 | 0 | 3 |
| CLSPN | SLC16A2 | 0.795382 | 3 | 0 | 3 |
| CLSPN | UCK2 | 0.793942 | 3 | 0 | 3 |
| CLSPN | ZNF707 | 0.788215 | 3 | 0 | 3 |
| CLSPN | MMS22L | 0.782449 | 3 | 0 | 3 |
| CLSPN | PSMG3 | 0.779243 | 6 | 0 | 6 |
| CLSPN | IFFO2 | 0.778612 | 3 | 0 | 3 |
| CLSPN | EBNA1BP2 | 0.776568 | 3 | 0 | 3 |
| CLSPN | THOC6 | 0.77192 | 6 | 0 | 6 |
| CLSPN | FAM89A | 0.77177 | 3 | 0 | 3 |
| CLSPN | DKC1 | 0.76897 | 3 | 0 | 3 |
| CLSPN | ORAI1 | 0.768676 | 3 | 0 | 3 |
| CLSPN | KTI12 | 0.768327 | 3 | 0 | 3 |
| CLSPN | TRAF7 | 0.767555 | 4 | 0 | 4 |
| CLSPN | SLC3A2 | 0.763262 | 6 | 0 | 6 |
| CLSPN | TRMT112 | 0.762178 | 6 | 0 | 6 |
| CLSPN | NCAPG2 | 0.755035 | 7 | 0 | 7 |
| CLSPN | CEP55 | 0.753986 | 7 | 0 | 7 |
For details and further investigation, click here
