CEP55

 

Full name: centrosomal protein 55 Alias Symbol: FLJ10540|CT111
Type: protein-coding gene Cytoband: 10q23.33
Entrez ID: 55165 HGNC ID: HGNC:1161 Ensembl Gene: ENSG00000138180 OMIM ID: 610000
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of CEP55:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 CEP55 55165 218542_at 1.8193 0.0400
GSE20347 CEP55 55165 218542_at 2.0790 0.0000
GSE23400 CEP55 55165 218542_at 2.0649 0.0000
GSE26886 CEP55 55165 218542_at 0.3367 0.3792
GSE29001 CEP55 55165 218542_at 2.0757 0.0000
GSE38129 CEP55 55165 218542_at 2.5962 0.0000
GSE45670 CEP55 55165 218542_at 1.9967 0.0000
GSE53622 CEP55 55165 2308 2.0121 0.0000
GSE53624 CEP55 55165 2308 2.2077 0.0000
GSE63941 CEP55 55165 218542_at 2.4494 0.0020
GSE77861 CEP55 55165 218542_at 1.8829 0.0084
GSE97050 CEP55 55165 A_33_P3291831 2.7113 0.0717
SRP007169 CEP55 55165 RNAseq 3.4260 0.0000
SRP008496 CEP55 55165 RNAseq 3.2714 0.0000
SRP064894 CEP55 55165 RNAseq 1.8130 0.0000
SRP133303 CEP55 55165 RNAseq 2.4800 0.0000
SRP159526 CEP55 55165 RNAseq 1.5575 0.0000
SRP193095 CEP55 55165 RNAseq 1.5185 0.0000
SRP219564 CEP55 55165 RNAseq 1.6669 0.0380
TCGA CEP55 55165 RNAseq 1.2825 0.0000

Upregulated datasets: 18; Downregulated datasets: 0.  

 

Survival by CEP55 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of CEP55:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 CEP55 55165 0 8 22
GSE20123 CEP55 55165 0 7 23
GSE43470 CEP55 55165 0 7 36
GSE46452 CEP55 55165 1 11 47
GSE47630 CEP55 55165 2 14 24
GSE54993 CEP55 55165 7 0 63
GSE54994 CEP55 55165 1 10 42
GSE60625 CEP55 55165 0 0 11
GSE74703 CEP55 55165 0 5 31
GSE74704 CEP55 55165 0 4 16
TCGA CEP55 55165 6 26 64

Total number of gains: 17; Total number of losses: 92; Total Number of normals: 379.  

 

Somatic mutations of CEP55:

 

Generating mutation plots.

 

Highly correlated genes for CEP55:

 

Showing top 20/2217 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
CEP55CDK10.88576212012
CEP55NEK20.8698113013
CEP55KIF140.86484113012
CEP55NCAPH0.859244909
CEP55PRC10.85298213013
CEP55BUB10.85025211011
CEP55KIF20A0.8491313013
CEP55BUB1B0.8465131009
CEP55KIF110.84445813013
CEP55CCNB20.84391312012
CEP55CDKN30.84342513013
CEP55TOP2A0.84289313013
CEP55UBE2C0.84231113013
CEP55KIF230.8411713012
CEP55TPX20.84062313012
CEP55AURKB0.83831813013
CEP55ASPM0.8357713012
CEP55MKI670.83399113012
CEP55MELK0.83210213012
CEP55CDC200.83050112011

For details and further investigation, click here