TRMT112

 

Full name: tRNA methyltransferase subunit 11-2 Alias Symbol: HSPC152|HSPC170|TRM112|TRMT11-2|hTrm112
Type: protein-coding gene Cytoband: 11q13.1
Entrez ID: 51504 HGNC ID: HGNC:26940 Ensembl Gene: ENSG00000173113 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of TRMT112:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TRMT112 51504 217774_s_at 0.4779 0.1327
GSE20347 TRMT112 51504 217774_s_at 0.5470 0.0010
GSE23400 TRMT112 51504 217774_s_at 0.6694 0.0000
GSE26886 TRMT112 51504 217774_s_at 0.3813 0.0773
GSE29001 TRMT112 51504 217774_s_at 0.5016 0.1501
GSE38129 TRMT112 51504 217774_s_at 0.5752 0.0000
GSE45670 TRMT112 51504 217774_s_at 0.4088 0.0123
GSE53622 TRMT112 51504 53868 0.8416 0.0000
GSE53624 TRMT112 51504 53868 1.1044 0.0000
GSE63941 TRMT112 51504 217774_s_at 0.8289 0.0038
GSE77861 TRMT112 51504 217774_s_at 0.6631 0.0035
GSE97050 TRMT112 51504 A_23_P12992 0.5399 0.1581
SRP007169 TRMT112 51504 RNAseq 0.0987 0.7797
SRP008496 TRMT112 51504 RNAseq 0.0485 0.8147
SRP064894 TRMT112 51504 RNAseq 0.4845 0.0633
SRP133303 TRMT112 51504 RNAseq 0.4661 0.0375
SRP159526 TRMT112 51504 RNAseq 0.5038 0.0002
SRP193095 TRMT112 51504 RNAseq 0.3621 0.0120
SRP219564 TRMT112 51504 RNAseq 0.4263 0.2112
TCGA TRMT112 51504 RNAseq 0.3482 0.0000

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by TRMT112 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of TRMT112:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TRMT112 51504 6 5 19
GSE20123 TRMT112 51504 6 5 19
GSE43470 TRMT112 51504 1 3 39
GSE46452 TRMT112 51504 8 4 47
GSE47630 TRMT112 51504 4 6 30
GSE54993 TRMT112 51504 3 0 67
GSE54994 TRMT112 51504 5 5 43
GSE60625 TRMT112 51504 0 3 8
GSE74703 TRMT112 51504 1 1 34
GSE74704 TRMT112 51504 4 3 13
TCGA TRMT112 51504 21 9 66

Total number of gains: 59; Total number of losses: 44; Total Number of normals: 385.  

 

Somatic mutations of TRMT112:

 

Generating mutation plots.

 

Highly correlated genes for TRMT112:

 

Showing top 20/1825 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TRMT112NEDD10.776854606
TRMT112SOCS70.766503303
TRMT112TUBB2B0.765703303
TRMT112CLSPN0.762178606
TRMT112FADS10.754187303
TRMT112YIF1A0.74896711011
TRMT112RAB340.743466303
TRMT112BANF10.73799413011
TRMT112NONO0.729154808
TRMT112PFDN20.72904611011
TRMT112YWHAG0.728954505
TRMT112STIP10.72736313013
TRMT112PSMG30.726079605
TRMT112EXOC30.724535303
TRMT112POLR2G0.72345812011
TRMT112VAX10.721137303
TRMT112ZNF7070.720223303
TRMT112GANAB0.71957612012
TRMT112KDM1A0.7190511008
TRMT112NOP580.715496504

For details and further investigation, click here