NCAPG2

 

Full name: non-SMC condensin II complex subunit G2 Alias Symbol: FLJ20311|MTB|CAP-G2|hCAP-G2
Type: protein-coding gene Cytoband: 7q36.3
Entrez ID: 54892 HGNC ID: HGNC:21904 Ensembl Gene: ENSG00000146918 OMIM ID: 608532
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of NCAPG2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 NCAPG2 54892 219588_s_at 0.9422 0.0674
GSE20347 NCAPG2 54892 219588_s_at 1.1806 0.0000
GSE23400 NCAPG2 54892 219588_s_at 0.9711 0.0000
GSE26886 NCAPG2 54892 219588_s_at -0.2512 0.2002
GSE29001 NCAPG2 54892 219588_s_at 0.9661 0.0002
GSE38129 NCAPG2 54892 219588_s_at 1.5028 0.0000
GSE45670 NCAPG2 54892 219588_s_at 0.7979 0.0034
GSE53622 NCAPG2 54892 53218 0.9163 0.0000
GSE53624 NCAPG2 54892 53218 1.2975 0.0000
GSE63941 NCAPG2 54892 219588_s_at 1.1269 0.0742
GSE77861 NCAPG2 54892 219588_s_at 0.8626 0.0092
GSE97050 NCAPG2 54892 A_33_P3659876 1.0712 0.1043
SRP007169 NCAPG2 54892 RNAseq 2.2696 0.0000
SRP008496 NCAPG2 54892 RNAseq 1.7741 0.0000
SRP064894 NCAPG2 54892 RNAseq 1.3617 0.0001
SRP133303 NCAPG2 54892 RNAseq 1.1660 0.0000
SRP159526 NCAPG2 54892 RNAseq 0.4753 0.1081
SRP193095 NCAPG2 54892 RNAseq 0.8569 0.0000
SRP219564 NCAPG2 54892 RNAseq 0.5990 0.2528
TCGA NCAPG2 54892 RNAseq 0.5754 0.0000

Upregulated datasets: 7; Downregulated datasets: 0.  

 

Survival by NCAPG2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of NCAPG2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 NCAPG2 54892 3 3 24
GSE20123 NCAPG2 54892 2 3 25
GSE43470 NCAPG2 54892 2 5 36
GSE46452 NCAPG2 54892 7 2 50
GSE47630 NCAPG2 54892 6 9 25
GSE54993 NCAPG2 54892 3 3 64
GSE54994 NCAPG2 54892 8 9 36
GSE60625 NCAPG2 54892 0 0 11
GSE74703 NCAPG2 54892 2 4 30
GSE74704 NCAPG2 54892 1 3 16
TCGA NCAPG2 54892 28 26 42

Total number of gains: 62; Total number of losses: 67; Total Number of normals: 359.  

 

Somatic mutations of NCAPG2:

 

Generating mutation plots.

 

Highly correlated genes for NCAPG2:

 

Showing top 20/1843 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
NCAPG2UBE2C0.82298811011
NCAPG2CENPF0.82012211011
NCAPG2DNMT10.81585911011
NCAPG2HJURP0.81539711011
NCAPG2NCAPH0.808892808
NCAPG2CBX30.805949909
NCAPG2ATAD20.80494612011
NCAPG2STIL0.80380411011
NCAPG2KIF20A0.80327511011
NCAPG2PRC10.80317312011
NCAPG2KNTC10.80042211011
NCAPG2TPX20.80032212012
NCAPG2GINS10.79677511011
NCAPG2KIF2C0.79580511011
NCAPG2BLM0.79498611011
NCAPG2ASPM0.79449511011
NCAPG2MMS22L0.793723303
NCAPG2KIF140.79197612012
NCAPG2CDC200.79149510010
NCAPG2BUB10.7903591009

For details and further investigation, click here