| Full name: calponin 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 19p13.3 | ||
| Entrez ID: 1265 | HGNC ID: HGNC:2156 | Ensembl Gene: ENSG00000064666 | OMIM ID: 602373 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of CNN2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CNN2 | 1265 | 201605_x_at | 0.3224 | 0.3970 | |
| GSE20347 | CNN2 | 1265 | 201605_x_at | 0.0552 | 0.7663 | |
| GSE23400 | CNN2 | 1265 | 201605_x_at | 0.1816 | 0.0015 | |
| GSE26886 | CNN2 | 1265 | 201605_x_at | 0.0557 | 0.8160 | |
| GSE29001 | CNN2 | 1265 | 201605_x_at | -0.2657 | 0.1654 | |
| GSE38129 | CNN2 | 1265 | 201605_x_at | 0.2803 | 0.0486 | |
| GSE45670 | CNN2 | 1265 | 201605_x_at | 0.4984 | 0.0002 | |
| GSE53622 | CNN2 | 1265 | 66252 | 0.1641 | 0.0066 | |
| GSE53624 | CNN2 | 1265 | 66252 | 0.0575 | 0.2977 | |
| GSE63941 | CNN2 | 1265 | 201605_x_at | 0.3597 | 0.2127 | |
| GSE77861 | CNN2 | 1265 | 201605_x_at | 0.1346 | 0.5352 | |
| GSE97050 | CNN2 | 1265 | A_24_P142743 | 0.7653 | 0.1057 | |
| SRP007169 | CNN2 | 1265 | RNAseq | 0.7659 | 0.0665 | |
| SRP008496 | CNN2 | 1265 | RNAseq | 0.8194 | 0.0004 | |
| SRP064894 | CNN2 | 1265 | RNAseq | 0.2322 | 0.2021 | |
| SRP133303 | CNN2 | 1265 | RNAseq | 0.6488 | 0.0003 | |
| SRP159526 | CNN2 | 1265 | RNAseq | -0.0153 | 0.9457 | |
| SRP193095 | CNN2 | 1265 | RNAseq | 0.3041 | 0.0356 | |
| SRP219564 | CNN2 | 1265 | RNAseq | 0.2811 | 0.4714 | |
| TCGA | CNN2 | 1265 | RNAseq | 0.2631 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CNN2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CNN2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CNN2 | 1265 | 4 | 6 | 20 | |
| GSE20123 | CNN2 | 1265 | 4 | 5 | 21 | |
| GSE43470 | CNN2 | 1265 | 1 | 9 | 33 | |
| GSE46452 | CNN2 | 1265 | 47 | 1 | 11 | |
| GSE47630 | CNN2 | 1265 | 5 | 7 | 28 | |
| GSE54993 | CNN2 | 1265 | 13 | 4 | 53 | |
| GSE54994 | CNN2 | 1265 | 8 | 15 | 30 | |
| GSE60625 | CNN2 | 1265 | 9 | 0 | 2 | |
| GSE74703 | CNN2 | 1265 | 1 | 7 | 28 | |
| GSE74704 | CNN2 | 1265 | 3 | 3 | 14 | |
| TCGA | CNN2 | 1265 | 8 | 25 | 63 |
Total number of gains: 103; Total number of losses: 82; Total Number of normals: 303.
Somatic mutations of CNN2:
Generating mutation plots.
Highly correlated genes for CNN2:
Showing top 20/282 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CNN2 | OGFOD2 | 0.735246 | 4 | 0 | 4 |
| CNN2 | FAM83A | 0.721901 | 3 | 0 | 3 |
| CNN2 | HAS3 | 0.67504 | 3 | 0 | 3 |
| CNN2 | CDCA2 | 0.673931 | 3 | 0 | 3 |
| CNN2 | CPSF3 | 0.667896 | 3 | 0 | 3 |
| CNN2 | NUDT14 | 0.667364 | 3 | 0 | 3 |
| CNN2 | IL11 | 0.664041 | 3 | 0 | 3 |
| CNN2 | SLC39A1 | 0.662355 | 4 | 0 | 4 |
| CNN2 | TSC22D4 | 0.656706 | 3 | 0 | 3 |
| CNN2 | NRSN2 | 0.656219 | 3 | 0 | 3 |
| CNN2 | ATAD3A | 0.649117 | 3 | 0 | 3 |
| CNN2 | OCIAD2 | 0.647804 | 3 | 0 | 3 |
| CNN2 | CMIP | 0.646975 | 5 | 0 | 4 |
| CNN2 | LDB1 | 0.642576 | 4 | 0 | 3 |
| CNN2 | CDK6 | 0.638058 | 4 | 0 | 3 |
| CNN2 | ITGA3 | 0.637788 | 4 | 0 | 4 |
| CNN2 | FUOM | 0.637653 | 3 | 0 | 3 |
| CNN2 | ATP2A2 | 0.634208 | 4 | 0 | 3 |
| CNN2 | TANC2 | 0.633002 | 4 | 0 | 4 |
| CNN2 | MAP2K2 | 0.631262 | 4 | 0 | 3 |
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