NUDT14

 

Full name: nudix hydrolase 14 Alias Symbol: UGPP
Type: protein-coding gene Cytoband: 14q32.33
Entrez ID: 256281 HGNC ID: HGNC:20141 Ensembl Gene: ENSG00000183828 OMIM ID: 609219
Drug and gene relationship at DGIdb

 

Expression of NUDT14:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 NUDT14 256281 231914_at 0.8500 0.2189
GSE26886 NUDT14 256281 231914_at 0.7019 0.0024
GSE45670 NUDT14 256281 231914_at 0.5195 0.0339
GSE53622 NUDT14 256281 25410 0.8273 0.0000
GSE53624 NUDT14 256281 25410 0.7301 0.0000
GSE63941 NUDT14 256281 231914_at 1.0046 0.1354
GSE77861 NUDT14 256281 231914_at 0.1344 0.6279
GSE97050 NUDT14 256281 A_23_P414978 0.0692 0.7968
SRP007169 NUDT14 256281 RNAseq 0.5539 0.2082
SRP008496 NUDT14 256281 RNAseq 0.4230 0.2996
SRP064894 NUDT14 256281 RNAseq 1.2912 0.0002
SRP133303 NUDT14 256281 RNAseq 0.4111 0.0452
SRP159526 NUDT14 256281 RNAseq 1.5646 0.0002
SRP193095 NUDT14 256281 RNAseq 0.4888 0.0015
SRP219564 NUDT14 256281 RNAseq 1.1597 0.0008
TCGA NUDT14 256281 RNAseq 0.1565 0.0593

Upregulated datasets: 3; Downregulated datasets: 0.  

 

Survival by NUDT14 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of NUDT14:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 NUDT14 256281 11 3 16
GSE20123 NUDT14 256281 10 2 18
GSE43470 NUDT14 256281 5 3 35
GSE46452 NUDT14 256281 18 4 37
GSE47630 NUDT14 256281 11 8 21
GSE54993 NUDT14 256281 5 10 55
GSE54994 NUDT14 256281 21 4 28
GSE60625 NUDT14 256281 0 2 9
GSE74703 NUDT14 256281 4 3 29
GSE74704 NUDT14 256281 5 2 13
TCGA NUDT14 256281 32 17 47

Total number of gains: 122; Total number of losses: 58; Total Number of normals: 308.  

 

Somatic mutations of NUDT14:

 

Generating mutation plots.

 

Highly correlated genes for NUDT14:

 

Showing top 20/683 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
NUDT14PLXNB20.748304303
NUDT14WDR200.721499404
NUDT14KTI120.708418303
NUDT14SNW10.700455505
NUDT14COMT0.688708303
NUDT14SLC25A170.688148404
NUDT14GLRX50.686935606
NUDT14TGFB10.680799403
NUDT14ZNF8390.679545404
NUDT14INO80B0.67598303
NUDT14PLEKHG30.672882403
NUDT14MARK30.671603504
NUDT14JAG20.668632808
NUDT14CNN20.667364303
NUDT14DNASE20.66318505
NUDT14ISCA20.662907606
NUDT14ALKBH10.66091605
NUDT14FUBP10.660853303
NUDT14MMP140.659607404
NUDT14CENPE0.659033303

For details and further investigation, click here