| Full name: tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | Alias Symbol: DKFZP564D166|FLJ10215|FLJ11824|KIAA1148|KIAA1636|rols|ROLSA | ||
| Type: protein-coding gene | Cytoband: 17q23.2-q23.3 | ||
| Entrez ID: 26115 | HGNC ID: HGNC:30212 | Ensembl Gene: ENSG00000170921 | OMIM ID: 615047 |
| Drug and gene relationship at DGIdb | |||
Expression of TANC2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TANC2 | 26115 | 224952_at | 0.9310 | 0.0636 | |
| GSE20347 | TANC2 | 26115 | 208425_s_at | 0.4870 | 0.0011 | |
| GSE23400 | TANC2 | 26115 | 208425_s_at | 0.0623 | 0.0964 | |
| GSE26886 | TANC2 | 26115 | 224952_at | 0.9898 | 0.0048 | |
| GSE29001 | TANC2 | 26115 | 208425_s_at | 0.3226 | 0.2171 | |
| GSE38129 | TANC2 | 26115 | 208425_s_at | 0.4956 | 0.0002 | |
| GSE45670 | TANC2 | 26115 | 224952_at | 0.9011 | 0.0009 | |
| GSE53622 | TANC2 | 26115 | 62574 | 1.1089 | 0.0000 | |
| GSE53624 | TANC2 | 26115 | 62574 | 1.2366 | 0.0000 | |
| GSE63941 | TANC2 | 26115 | 224952_at | -0.6731 | 0.3247 | |
| GSE77861 | TANC2 | 26115 | 224952_at | 1.0470 | 0.0421 | |
| GSE97050 | TANC2 | 26115 | A_24_P942068 | 0.6364 | 0.2494 | |
| SRP007169 | TANC2 | 26115 | RNAseq | 1.7808 | 0.0001 | |
| SRP008496 | TANC2 | 26115 | RNAseq | 1.8155 | 0.0000 | |
| SRP064894 | TANC2 | 26115 | RNAseq | 1.6430 | 0.0000 | |
| SRP133303 | TANC2 | 26115 | RNAseq | 1.5650 | 0.0000 | |
| SRP159526 | TANC2 | 26115 | RNAseq | 0.9100 | 0.0113 | |
| SRP193095 | TANC2 | 26115 | RNAseq | 1.2414 | 0.0000 | |
| SRP219564 | TANC2 | 26115 | RNAseq | 1.5452 | 0.0043 | |
| TCGA | TANC2 | 26115 | RNAseq | 0.3514 | 0.0000 |
Upregulated datasets: 9; Downregulated datasets: 0.
Survival by TANC2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TANC2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TANC2 | 26115 | 4 | 1 | 25 | |
| GSE20123 | TANC2 | 26115 | 4 | 1 | 25 | |
| GSE43470 | TANC2 | 26115 | 5 | 0 | 38 | |
| GSE46452 | TANC2 | 26115 | 31 | 0 | 28 | |
| GSE47630 | TANC2 | 26115 | 7 | 1 | 32 | |
| GSE54993 | TANC2 | 26115 | 2 | 5 | 63 | |
| GSE54994 | TANC2 | 26115 | 9 | 5 | 39 | |
| GSE60625 | TANC2 | 26115 | 4 | 0 | 7 | |
| GSE74703 | TANC2 | 26115 | 5 | 0 | 31 | |
| GSE74704 | TANC2 | 26115 | 3 | 1 | 16 | |
| TCGA | TANC2 | 26115 | 31 | 9 | 56 |
Total number of gains: 105; Total number of losses: 23; Total Number of normals: 360.
Somatic mutations of TANC2:
Generating mutation plots.
Highly correlated genes for TANC2:
Showing top 20/1616 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TANC2 | SPON2 | 0.754465 | 3 | 0 | 3 |
| TANC2 | ZNF707 | 0.748871 | 3 | 0 | 3 |
| TANC2 | SEC16A | 0.747736 | 3 | 0 | 3 |
| TANC2 | CAPN12 | 0.747187 | 3 | 0 | 3 |
| TANC2 | CYTH3 | 0.744415 | 4 | 0 | 4 |
| TANC2 | CYP27C1 | 0.737297 | 7 | 0 | 7 |
| TANC2 | FAM89A | 0.736216 | 3 | 0 | 3 |
| TANC2 | SAFB2 | 0.734673 | 3 | 0 | 3 |
| TANC2 | SLC23A2 | 0.733824 | 4 | 0 | 4 |
| TANC2 | ALG1 | 0.720561 | 3 | 0 | 3 |
| TANC2 | FBLIM1 | 0.718378 | 7 | 0 | 7 |
| TANC2 | POLR2A | 0.7183 | 3 | 0 | 3 |
| TANC2 | REC8 | 0.715503 | 3 | 0 | 3 |
| TANC2 | FLRT2 | 0.715422 | 3 | 0 | 3 |
| TANC2 | JKAMP | 0.711695 | 7 | 0 | 6 |
| TANC2 | TMEM138 | 0.70537 | 6 | 0 | 6 |
| TANC2 | GUCY1A2 | 0.704657 | 4 | 0 | 4 |
| TANC2 | PIP4K2B | 0.704346 | 3 | 0 | 3 |
| TANC2 | DEPDC1B | 0.704078 | 5 | 0 | 5 |
| TANC2 | ALPK2 | 0.698861 | 3 | 0 | 3 |
For details and further investigation, click here
