| Full name: TSC22 domain family member 4 | Alias Symbol: THG-1|TILZ2 | ||
| Type: protein-coding gene | Cytoband: 7q22.1 | ||
| Entrez ID: 81628 | HGNC ID: HGNC:21696 | Ensembl Gene: ENSG00000166925 | OMIM ID: 611914 |
| Drug and gene relationship at DGIdb | |||
Expression of TSC22D4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TSC22D4 | 81628 | 208104_s_at | 0.0145 | 0.9799 | |
| GSE20347 | TSC22D4 | 81628 | 208104_s_at | -0.2969 | 0.0037 | |
| GSE23400 | TSC22D4 | 81628 | 208104_s_at | -0.2647 | 0.0000 | |
| GSE26886 | TSC22D4 | 81628 | 208104_s_at | 0.1741 | 0.1918 | |
| GSE29001 | TSC22D4 | 81628 | 208104_s_at | -0.3177 | 0.0338 | |
| GSE38129 | TSC22D4 | 81628 | 208104_s_at | -0.3539 | 0.0006 | |
| GSE45670 | TSC22D4 | 81628 | 208104_s_at | -0.1643 | 0.1776 | |
| GSE53622 | TSC22D4 | 81628 | 83415 | -0.6267 | 0.0000 | |
| GSE53624 | TSC22D4 | 81628 | 83415 | -0.5687 | 0.0000 | |
| GSE63941 | TSC22D4 | 81628 | 208104_s_at | -0.0293 | 0.9082 | |
| GSE77861 | TSC22D4 | 81628 | 208104_s_at | -0.2000 | 0.3570 | |
| GSE97050 | TSC22D4 | 81628 | A_24_P200942 | 0.0018 | 0.9971 | |
| SRP007169 | TSC22D4 | 81628 | RNAseq | -2.7044 | 0.0000 | |
| SRP008496 | TSC22D4 | 81628 | RNAseq | -2.5686 | 0.0000 | |
| SRP064894 | TSC22D4 | 81628 | RNAseq | -0.7610 | 0.0049 | |
| SRP133303 | TSC22D4 | 81628 | RNAseq | -0.6703 | 0.0000 | |
| SRP159526 | TSC22D4 | 81628 | RNAseq | -1.0474 | 0.0001 | |
| SRP193095 | TSC22D4 | 81628 | RNAseq | -0.5830 | 0.0008 | |
| SRP219564 | TSC22D4 | 81628 | RNAseq | -0.6615 | 0.0616 | |
| TCGA | TSC22D4 | 81628 | RNAseq | 0.0732 | 0.1729 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by TSC22D4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TSC22D4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TSC22D4 | 81628 | 13 | 0 | 17 | |
| GSE20123 | TSC22D4 | 81628 | 13 | 0 | 17 | |
| GSE43470 | TSC22D4 | 81628 | 7 | 2 | 34 | |
| GSE46452 | TSC22D4 | 81628 | 11 | 1 | 47 | |
| GSE47630 | TSC22D4 | 81628 | 7 | 3 | 30 | |
| GSE54993 | TSC22D4 | 81628 | 1 | 9 | 60 | |
| GSE54994 | TSC22D4 | 81628 | 16 | 3 | 34 | |
| GSE60625 | TSC22D4 | 81628 | 0 | 0 | 11 | |
| GSE74703 | TSC22D4 | 81628 | 7 | 1 | 28 | |
| GSE74704 | TSC22D4 | 81628 | 9 | 0 | 11 | |
| TCGA | TSC22D4 | 81628 | 52 | 6 | 38 |
Total number of gains: 136; Total number of losses: 25; Total Number of normals: 327.
Somatic mutations of TSC22D4:
Generating mutation plots.
Highly correlated genes for TSC22D4:
Showing top 20/1035 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TSC22D4 | CRIP3 | 0.742536 | 3 | 0 | 3 |
| TSC22D4 | RIPK3 | 0.738441 | 3 | 0 | 3 |
| TSC22D4 | NIPAL1 | 0.729388 | 3 | 0 | 3 |
| TSC22D4 | DDI2 | 0.723337 | 3 | 0 | 3 |
| TSC22D4 | FAM166A | 0.71978 | 3 | 0 | 3 |
| TSC22D4 | ABHD12 | 0.718476 | 3 | 0 | 3 |
| TSC22D4 | SRP68 | 0.718263 | 4 | 0 | 4 |
| TSC22D4 | MZF1 | 0.713626 | 3 | 0 | 3 |
| TSC22D4 | RNF207 | 0.709294 | 3 | 0 | 3 |
| TSC22D4 | ZNF416 | 0.698324 | 3 | 0 | 3 |
| TSC22D4 | KLK14 | 0.696168 | 3 | 0 | 3 |
| TSC22D4 | MOSPD3 | 0.693858 | 11 | 0 | 10 |
| TSC22D4 | AHSP | 0.693595 | 4 | 0 | 3 |
| TSC22D4 | LTA4H | 0.692006 | 3 | 0 | 3 |
| TSC22D4 | ITGA8 | 0.687499 | 4 | 0 | 3 |
| TSC22D4 | DTX2 | 0.686027 | 7 | 0 | 7 |
| TSC22D4 | NUAK2 | 0.682789 | 3 | 0 | 3 |
| TSC22D4 | SESN2 | 0.6827 | 4 | 0 | 4 |
| TSC22D4 | KLF16 | 0.680665 | 4 | 0 | 3 |
| TSC22D4 | TMEM120A | 0.675303 | 6 | 0 | 6 |
For details and further investigation, click here
