CNNM1

 

Full name: cyclin and CBS domain divalent metal cation transport mediator 1 Alias Symbol: 
Type: protein-coding gene Cytoband: 10q24.2
Entrez ID: 26507 HGNC ID: HGNC:102 Ensembl Gene: ENSG00000119946 OMIM ID: 607802
Drug and gene relationship at DGIdb

 

Expression of CNNM1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 CNNM1 26507 220166_at -0.1673 0.6306
GSE20347 CNNM1 26507 220166_at -0.1425 0.2047
GSE23400 CNNM1 26507 220166_at -0.2087 0.0000
GSE26886 CNNM1 26507 220166_at -0.2026 0.0598
GSE29001 CNNM1 26507 220166_at -0.5314 0.0018
GSE38129 CNNM1 26507 220166_at -0.0563 0.6181
GSE45670 CNNM1 26507 220166_at 0.0780 0.4421
GSE63941 CNNM1 26507 220166_at 0.2584 0.3731
GSE77861 CNNM1 26507 220166_at -0.0504 0.6584
GSE97050 CNNM1 26507 A_23_P46947 0.2503 0.4717
SRP007169 CNNM1 26507 RNAseq 1.7919 0.0181
SRP133303 CNNM1 26507 RNAseq 0.6037 0.0984
SRP159526 CNNM1 26507 RNAseq 1.5135 0.0009
SRP193095 CNNM1 26507 RNAseq 0.9113 0.0000
SRP219564 CNNM1 26507 RNAseq 0.4447 0.3574
TCGA CNNM1 26507 RNAseq 0.3471 0.2891

Upregulated datasets: 2; Downregulated datasets: 0.  


 

Survival by CNNM1 expression:

 

TCGA

 

Note: Click image to view full size file.  


Copy number change of CNNM1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 CNNM1 26507 1 8 21
GSE20123 CNNM1 26507 1 7 22
GSE43470 CNNM1 26507 0 7 36
GSE46452 CNNM1 26507 0 11 48
GSE47630 CNNM1 26507 2 14 24
GSE54993 CNNM1 26507 8 0 62
GSE54994 CNNM1 26507 1 12 40
GSE60625 CNNM1 26507 0 0 11
GSE74703 CNNM1 26507 0 5 31
GSE74704 CNNM1 26507 0 4 16
TCGA CNNM1 26507 5 28 63

Total number of gains: 18; Total number of losses: 96; Total Number of normals: 374.  


 

Somatic mutations of CNNM1:

 

Generating mutation plots.

 

Highly correlated genes for CNNM1:

 

Showing top 20/258 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
CNNM1GPR320.678933303
CNNM1L1CAM0.654417403
CNNM1ADRA2A0.65384303
CNNM1CORO1B0.651024403
CNNM1PTGDS0.646314303
CNNM1VAMP20.643614303
CNNM1CD2440.639052403
CNNM1KIAA16140.637429303
CNNM1RAP1GAP0.635184303
CNNM1SIT10.633745303
CNNM1SST0.632273303
CNNM1NECAB20.631964303
CNNM1DRP20.630238807
CNNM1BTN1A10.627001404
CNNM1USH1G0.625351303
CNNM1CEACAM30.625025403
CNNM1MATN10.624659303
CNNM1DPEP10.618477404
CNNM1FSHR0.616412403
CNNM1SPAG60.61457403

For details and further investigation, click here