| Full name: sperm associated antigen 6 | Alias Symbol: Repro-SA-1|pf16|CT141 | ||
| Type: protein-coding gene | Cytoband: 10p12.2 | ||
| Entrez ID: 9576 | HGNC ID: HGNC:11215 | Ensembl Gene: ENSG00000077327 | OMIM ID: 605730 |
| Drug and gene relationship at DGIdb | |||
Expression of SPAG6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SPAG6 | 9576 | 210032_s_at | 0.0085 | 0.9819 | |
| GSE20347 | SPAG6 | 9576 | 210032_s_at | -0.0470 | 0.4402 | |
| GSE23400 | SPAG6 | 9576 | 210033_s_at | -0.2225 | 0.0000 | |
| GSE26886 | SPAG6 | 9576 | 210033_s_at | -0.0984 | 0.5746 | |
| GSE29001 | SPAG6 | 9576 | 210033_s_at | -0.4105 | 0.0106 | |
| GSE38129 | SPAG6 | 9576 | 210032_s_at | -0.0205 | 0.8268 | |
| GSE45670 | SPAG6 | 9576 | 210033_s_at | -0.0661 | 0.5316 | |
| GSE53622 | SPAG6 | 9576 | 100027 | 0.3890 | 0.0358 | |
| GSE53624 | SPAG6 | 9576 | 100027 | 0.1061 | 0.3240 | |
| GSE63941 | SPAG6 | 9576 | 210032_s_at | 0.0442 | 0.7819 | |
| GSE77861 | SPAG6 | 9576 | 210033_s_at | -0.2996 | 0.0219 | |
| SRP133303 | SPAG6 | 9576 | RNAseq | 0.2888 | 0.2159 | |
| TCGA | SPAG6 | 9576 | RNAseq | 0.0491 | 0.9566 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SPAG6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SPAG6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SPAG6 | 9576 | 5 | 8 | 17 | |
| GSE20123 | SPAG6 | 9576 | 5 | 7 | 18 | |
| GSE43470 | SPAG6 | 9576 | 4 | 4 | 35 | |
| GSE46452 | SPAG6 | 9576 | 1 | 14 | 44 | |
| GSE47630 | SPAG6 | 9576 | 5 | 15 | 20 | |
| GSE54993 | SPAG6 | 9576 | 10 | 0 | 60 | |
| GSE54994 | SPAG6 | 9576 | 3 | 9 | 41 | |
| GSE60625 | SPAG6 | 9576 | 0 | 0 | 11 | |
| GSE74703 | SPAG6 | 9576 | 3 | 2 | 31 | |
| GSE74704 | SPAG6 | 9576 | 0 | 6 | 14 | |
| TCGA | SPAG6 | 9576 | 18 | 25 | 53 |
Total number of gains: 54; Total number of losses: 90; Total Number of normals: 344.
Somatic mutations of SPAG6:
Generating mutation plots.
Highly correlated genes for SPAG6:
Showing top 20/489 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SPAG6 | THRB | 0.74484 | 3 | 0 | 3 |
| SPAG6 | PSG5 | 0.680635 | 3 | 0 | 3 |
| SPAG6 | CRYL1 | 0.666632 | 3 | 0 | 3 |
| SPAG6 | C21orf62 | 0.665648 | 3 | 0 | 3 |
| SPAG6 | SH3GL1 | 0.665242 | 4 | 0 | 4 |
| SPAG6 | ZNF717 | 0.663951 | 4 | 0 | 3 |
| SPAG6 | MYL1 | 0.663833 | 3 | 0 | 3 |
| SPAG6 | CSPG5 | 0.663727 | 4 | 0 | 4 |
| SPAG6 | GAB2 | 0.661863 | 3 | 0 | 3 |
| SPAG6 | PRSS3 | 0.66143 | 3 | 0 | 3 |
| SPAG6 | E2F2 | 0.658665 | 3 | 0 | 3 |
| SPAG6 | GABRA2 | 0.658546 | 3 | 0 | 3 |
| SPAG6 | GSN-AS1 | 0.657335 | 4 | 0 | 3 |
| SPAG6 | CA4 | 0.657321 | 3 | 0 | 3 |
| SPAG6 | TGM3 | 0.652893 | 3 | 0 | 3 |
| SPAG6 | PHOX2A | 0.651856 | 3 | 0 | 3 |
| SPAG6 | LCNL1 | 0.651742 | 3 | 0 | 3 |
| SPAG6 | FSCN3 | 0.650396 | 3 | 0 | 3 |
| SPAG6 | KLK11 | 0.650315 | 3 | 0 | 3 |
| SPAG6 | ALDH3B2 | 0.649682 | 3 | 0 | 3 |
For details and further investigation, click here
