| Full name: cyclin and CBS domain divalent metal cation transport mediator 4 | Alias Symbol: KIAA1592 | ||
| Type: protein-coding gene | Cytoband: 2q11.2 | ||
| Entrez ID: 26504 | HGNC ID: HGNC:105 | Ensembl Gene: ENSG00000158158 | OMIM ID: 607805 |
| Drug and gene relationship at DGIdb | |||
Expression of CNNM4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CNNM4 | 26504 | 218900_at | 0.7772 | 0.0253 | |
| GSE20347 | CNNM4 | 26504 | 218900_at | 0.3896 | 0.0017 | |
| GSE23400 | CNNM4 | 26504 | 218900_at | -0.0199 | 0.7387 | |
| GSE26886 | CNNM4 | 26504 | 218900_at | 0.1502 | 0.3535 | |
| GSE29001 | CNNM4 | 26504 | 218900_at | 0.0553 | 0.8196 | |
| GSE38129 | CNNM4 | 26504 | 218900_at | 0.3653 | 0.0004 | |
| GSE45670 | CNNM4 | 26504 | 218900_at | 0.2044 | 0.1568 | |
| GSE53622 | CNNM4 | 26504 | 12162 | 0.1893 | 0.0885 | |
| GSE53624 | CNNM4 | 26504 | 12162 | 0.1401 | 0.0341 | |
| GSE63941 | CNNM4 | 26504 | 218900_at | 1.0426 | 0.0321 | |
| GSE77861 | CNNM4 | 26504 | 218900_at | 0.2879 | 0.0829 | |
| GSE97050 | CNNM4 | 26504 | A_23_P119923 | 0.0480 | 0.8585 | |
| SRP007169 | CNNM4 | 26504 | RNAseq | -0.3101 | 0.3621 | |
| SRP008496 | CNNM4 | 26504 | RNAseq | -0.3334 | 0.0666 | |
| SRP064894 | CNNM4 | 26504 | RNAseq | -0.6128 | 0.0181 | |
| SRP133303 | CNNM4 | 26504 | RNAseq | 0.3624 | 0.0617 | |
| SRP159526 | CNNM4 | 26504 | RNAseq | 0.8988 | 0.0825 | |
| SRP193095 | CNNM4 | 26504 | RNAseq | -0.1948 | 0.2717 | |
| SRP219564 | CNNM4 | 26504 | RNAseq | 0.1144 | 0.8355 | |
| TCGA | CNNM4 | 26504 | RNAseq | -0.0016 | 0.9793 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by CNNM4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CNNM4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CNNM4 | 26504 | 6 | 2 | 22 | |
| GSE20123 | CNNM4 | 26504 | 6 | 2 | 22 | |
| GSE43470 | CNNM4 | 26504 | 2 | 3 | 38 | |
| GSE46452 | CNNM4 | 26504 | 2 | 3 | 54 | |
| GSE47630 | CNNM4 | 26504 | 7 | 0 | 33 | |
| GSE54993 | CNNM4 | 26504 | 0 | 6 | 64 | |
| GSE54994 | CNNM4 | 26504 | 11 | 0 | 42 | |
| GSE60625 | CNNM4 | 26504 | 0 | 3 | 8 | |
| GSE74703 | CNNM4 | 26504 | 2 | 2 | 32 | |
| GSE74704 | CNNM4 | 26504 | 4 | 1 | 15 | |
| TCGA | CNNM4 | 26504 | 35 | 3 | 58 |
Total number of gains: 75; Total number of losses: 25; Total Number of normals: 388.
Somatic mutations of CNNM4:
Generating mutation plots.
Highly correlated genes for CNNM4:
Showing top 20/464 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CNNM4 | EIF1AD | 0.747174 | 3 | 0 | 3 |
| CNNM4 | PLAU | 0.67968 | 4 | 0 | 4 |
| CNNM4 | FEN1 | 0.67849 | 4 | 0 | 4 |
| CNNM4 | TIGD2 | 0.673939 | 3 | 0 | 3 |
| CNNM4 | CFL1 | 0.673401 | 3 | 0 | 3 |
| CNNM4 | PPP1R14B | 0.667007 | 4 | 0 | 3 |
| CNNM4 | PRKDC | 0.665197 | 5 | 0 | 4 |
| CNNM4 | SF3B4 | 0.66368 | 5 | 0 | 5 |
| CNNM4 | RUVBL1 | 0.663479 | 5 | 0 | 5 |
| CNNM4 | SPATA24 | 0.661805 | 3 | 0 | 3 |
| CNNM4 | KIF18B | 0.661029 | 5 | 0 | 5 |
| CNNM4 | CDCA5 | 0.657095 | 4 | 0 | 3 |
| CNNM4 | NCAPH | 0.654885 | 6 | 0 | 5 |
| CNNM4 | C1orf112 | 0.65115 | 6 | 0 | 6 |
| CNNM4 | DAGLB | 0.650603 | 5 | 0 | 4 |
| CNNM4 | TPX2 | 0.648026 | 6 | 0 | 5 |
| CNNM4 | DDX55 | 0.647296 | 3 | 0 | 3 |
| CNNM4 | TMEM161A | 0.644133 | 3 | 0 | 3 |
| CNNM4 | CKAP2L | 0.643635 | 4 | 0 | 4 |
| CNNM4 | DESI2 | 0.643403 | 4 | 0 | 4 |
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