| Full name: non-SMC condensin I complex subunit H | Alias Symbol: CAP-H|hCAP-H | ||
| Type: protein-coding gene | Cytoband: 2q11.2 | ||
| Entrez ID: 23397 | HGNC ID: HGNC:1112 | Ensembl Gene: ENSG00000121152 | OMIM ID: 602332 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of NCAPH:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NCAPH | 23397 | 212949_at | 1.4474 | 0.0343 | |
| GSE20347 | NCAPH | 23397 | 212949_at | 1.1968 | 0.0000 | |
| GSE23400 | NCAPH | 23397 | 212949_at | 0.5130 | 0.0000 | |
| GSE26886 | NCAPH | 23397 | 212949_at | 1.0097 | 0.0007 | |
| GSE29001 | NCAPH | 23397 | 212949_at | 0.9021 | 0.0002 | |
| GSE38129 | NCAPH | 23397 | 212949_at | 1.4346 | 0.0000 | |
| GSE45670 | NCAPH | 23397 | 212949_at | 1.3891 | 0.0000 | |
| GSE63941 | NCAPH | 23397 | 212949_at | 3.0193 | 0.0001 | |
| GSE77861 | NCAPH | 23397 | 212949_at | 0.8519 | 0.0009 | |
| GSE97050 | NCAPH | 23397 | A_33_P3230259 | -0.0957 | 0.7307 | |
| SRP007169 | NCAPH | 23397 | RNAseq | 2.3340 | 0.0000 | |
| SRP008496 | NCAPH | 23397 | RNAseq | 1.9181 | 0.0000 | |
| SRP064894 | NCAPH | 23397 | RNAseq | 1.5582 | 0.0000 | |
| SRP133303 | NCAPH | 23397 | RNAseq | 1.1830 | 0.0000 | |
| SRP159526 | NCAPH | 23397 | RNAseq | 1.6422 | 0.0001 | |
| SRP193095 | NCAPH | 23397 | RNAseq | 0.8816 | 0.0000 | |
| SRP219564 | NCAPH | 23397 | RNAseq | 1.6472 | 0.0130 | |
| TCGA | NCAPH | 23397 | RNAseq | 1.4330 | 0.0000 |
Upregulated datasets: 13; Downregulated datasets: 0.
Survival by NCAPH expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of NCAPH:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NCAPH | 23397 | 6 | 2 | 22 | |
| GSE20123 | NCAPH | 23397 | 6 | 2 | 22 | |
| GSE43470 | NCAPH | 23397 | 2 | 3 | 38 | |
| GSE46452 | NCAPH | 23397 | 2 | 3 | 54 | |
| GSE47630 | NCAPH | 23397 | 7 | 0 | 33 | |
| GSE54993 | NCAPH | 23397 | 0 | 6 | 64 | |
| GSE54994 | NCAPH | 23397 | 11 | 0 | 42 | |
| GSE60625 | NCAPH | 23397 | 0 | 3 | 8 | |
| GSE74703 | NCAPH | 23397 | 2 | 2 | 32 | |
| GSE74704 | NCAPH | 23397 | 4 | 1 | 15 | |
| TCGA | NCAPH | 23397 | 36 | 3 | 57 |
Total number of gains: 76; Total number of losses: 25; Total Number of normals: 387.
Somatic mutations of NCAPH:
Generating mutation plots.
Highly correlated genes for NCAPH:
Showing top 20/1564 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NCAPH | BUB1 | 0.918518 | 7 | 0 | 7 |
| NCAPH | UBE2T | 0.864151 | 5 | 0 | 5 |
| NCAPH | UHRF1 | 0.861015 | 5 | 0 | 5 |
| NCAPH | CEP55 | 0.859244 | 9 | 0 | 9 |
| NCAPH | AURKB | 0.858584 | 9 | 0 | 9 |
| NCAPH | BUB1B | 0.857734 | 9 | 0 | 9 |
| NCAPH | MTFR2 | 0.855967 | 5 | 0 | 5 |
| NCAPH | TPX2 | 0.855709 | 9 | 0 | 9 |
| NCAPH | RAD51AP1 | 0.854781 | 9 | 0 | 9 |
| NCAPH | CDCA3 | 0.852824 | 9 | 0 | 9 |
| NCAPH | FOXM1 | 0.851908 | 9 | 0 | 9 |
| NCAPH | UBE2C | 0.847465 | 9 | 0 | 9 |
| NCAPH | TRIP13 | 0.847199 | 9 | 0 | 9 |
| NCAPH | CDCA2 | 0.845739 | 5 | 0 | 5 |
| NCAPH | NEK2 | 0.845592 | 9 | 0 | 9 |
| NCAPH | CENPF | 0.844242 | 9 | 0 | 9 |
| NCAPH | KIF18B | 0.843616 | 9 | 0 | 9 |
| NCAPH | KIF14 | 0.842841 | 9 | 0 | 9 |
| NCAPH | CDC20 | 0.841786 | 9 | 0 | 9 |
| NCAPH | MCM2 | 0.839345 | 9 | 0 | 9 |
For details and further investigation, click here
