DAGLB

 

Full name: diacylglycerol lipase beta Alias Symbol: KCCR13L|DAGLBETA
Type: protein-coding gene Cytoband: 7p22.1
Entrez ID: 221955 HGNC ID: HGNC:28923 Ensembl Gene: ENSG00000164535 OMIM ID: 614016
Drug and gene relationship at DGIdb

 

Expression of DAGLB:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 DAGLB 221955 225832_s_at 0.4413 0.1823
GSE26886 DAGLB 221955 225832_s_at -0.5730 0.0039
GSE45670 DAGLB 221955 225832_s_at 0.4085 0.0075
GSE53622 DAGLB 221955 28299 0.4514 0.0000
GSE53624 DAGLB 221955 28299 0.6585 0.0000
GSE63941 DAGLB 221955 225832_s_at 1.3053 0.0010
GSE77861 DAGLB 221955 226640_at 0.2092 0.1658
GSE97050 DAGLB 221955 A_23_P8539 0.5046 0.2144
SRP007169 DAGLB 221955 RNAseq -0.2544 0.5991
SRP008496 DAGLB 221955 RNAseq -0.1913 0.5125
SRP064894 DAGLB 221955 RNAseq 0.3987 0.0351
SRP133303 DAGLB 221955 RNAseq 0.3392 0.0529
SRP159526 DAGLB 221955 RNAseq -0.0215 0.9471
SRP193095 DAGLB 221955 RNAseq -0.0079 0.9389
SRP219564 DAGLB 221955 RNAseq 0.7984 0.1061
TCGA DAGLB 221955 RNAseq 0.1197 0.0451

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by DAGLB expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of DAGLB:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 DAGLB 221955 14 1 15
GSE20123 DAGLB 221955 14 1 15
GSE43470 DAGLB 221955 6 1 36
GSE46452 DAGLB 221955 13 1 45
GSE47630 DAGLB 221955 9 1 30
GSE54993 DAGLB 221955 0 6 64
GSE54994 DAGLB 221955 20 1 32
GSE60625 DAGLB 221955 0 0 11
GSE74703 DAGLB 221955 6 0 30
GSE74704 DAGLB 221955 9 0 11
TCGA DAGLB 221955 56 4 36

Total number of gains: 147; Total number of losses: 16; Total Number of normals: 325.  

 

Somatic mutations of DAGLB:

 

Generating mutation plots.

 

Highly correlated genes for DAGLB:

 

Showing top 20/220 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
DAGLBTPD520.681714303
DAGLBUBR40.659447303
DAGLBCELSR10.655892403
DAGLBSOGA10.654144303
DAGLBLSR0.651152605
DAGLBCNNM40.650603504
DAGLBNUCB10.6419303
DAGLBCLN60.638319303
DAGLBEIF3B0.63549706
DAGLBLASP10.635058303
DAGLBSPATA240.630875303
DAGLBUSP210.62995504
DAGLBCOPA0.624895303
DAGLBAKT1S10.622825403
DAGLBEIF2AK10.620552805
DAGLBPFN10.619185403
DAGLBLRP50.616246303
DAGLBPPP1R14B0.614977504
DAGLBNELFCD0.612445403
DAGLBPOGK0.612009403

For details and further investigation, click here