KIF18B

 

Full name: kinesin family member 18B Alias Symbol: 
Type: protein-coding gene Cytoband: 17q21.31
Entrez ID: 146909 HGNC ID: HGNC:27102 Ensembl Gene: ENSG00000186185 OMIM ID: 614570
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of KIF18B:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 KIF18B 146909 222039_at 1.3511 0.0132
GSE20347 KIF18B 146909 222039_at 1.3567 0.0000
GSE23400 KIF18B 146909 222039_at 0.9044 0.0000
GSE26886 KIF18B 146909 222039_at 0.9499 0.0026
GSE29001 KIF18B 146909 222039_at 1.5163 0.0002
GSE38129 KIF18B 146909 222039_at 1.5815 0.0000
GSE45670 KIF18B 146909 222039_at 1.4413 0.0000
GSE53622 KIF18B 146909 67072 0.9473 0.0000
GSE53624 KIF18B 146909 90234 1.0500 0.0000
GSE63941 KIF18B 146909 222039_at 3.0027 0.0000
GSE77861 KIF18B 146909 222039_at 1.1759 0.0018
GSE97050 KIF18B 146909 A_33_P3421338 1.5503 0.1776
SRP007169 KIF18B 146909 RNAseq 2.2970 0.0000
SRP008496 KIF18B 146909 RNAseq 1.6805 0.0000
SRP064894 KIF18B 146909 RNAseq 1.8908 0.0000
SRP133303 KIF18B 146909 RNAseq 1.5292 0.0000
SRP159526 KIF18B 146909 RNAseq 2.1538 0.0001
SRP193095 KIF18B 146909 RNAseq 0.9993 0.0000
SRP219564 KIF18B 146909 RNAseq 1.8876 0.0133
TCGA KIF18B 146909 RNAseq 1.2993 0.0000

Upregulated datasets: 15; Downregulated datasets: 0.  

 

Survival by KIF18B expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of KIF18B:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 KIF18B 146909 6 2 22
GSE20123 KIF18B 146909 6 2 22
GSE43470 KIF18B 146909 1 2 40
GSE46452 KIF18B 146909 32 0 27
GSE47630 KIF18B 146909 9 0 31
GSE54993 KIF18B 146909 3 4 63
GSE54994 KIF18B 146909 9 6 38
GSE60625 KIF18B 146909 4 0 7
GSE74703 KIF18B 146909 1 1 34
GSE74704 KIF18B 146909 4 1 15
TCGA KIF18B 146909 27 6 63

Total number of gains: 102; Total number of losses: 24; Total Number of normals: 362.  

 

Somatic mutations of KIF18B:

 

Generating mutation plots.

 

Highly correlated genes for KIF18B:

 

Showing top 20/1427 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
KIF18BUHRF10.866921707
KIF18BBUB1B0.86519310010
KIF18BFOXM10.86466911011
KIF18BAURKA0.85555810010
KIF18BTTK0.8481510010
KIF18BNCAPH0.843616909
KIF18BFEN10.84167510010
KIF18BBUB10.841554909
KIF18BORC60.83541611011
KIF18BASPM0.83214410010
KIF18BCDCA20.823043505
KIF18BRACGAP10.820164908
KIF18BKIF4A0.81889712011
KIF18BNUF20.817985706
KIF18BRAD51AP10.8121312011
KIF18BTOP2A0.81175211010
KIF18BTROAP0.81115610010
KIF18BNUSAP10.80758211010
KIF18BMCM20.80381312011
KIF18BKIF140.80379412010

For details and further investigation, click here