| Full name: zinc finger protein 469 | Alias Symbol: KIAA1858 | ||
| Type: protein-coding gene | Cytoband: 16q24.2 | ||
| Entrez ID: 84627 | HGNC ID: HGNC:23216 | Ensembl Gene: ENSG00000225614 | OMIM ID: 612078 |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF469:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF469 | 84627 | 230440_at | 0.8977 | 0.0623 | |
| GSE26886 | ZNF469 | 84627 | 230440_at | 0.8725 | 0.0004 | |
| GSE45670 | ZNF469 | 84627 | 230440_at | 0.9064 | 0.0043 | |
| GSE53622 | ZNF469 | 84627 | 48122 | 2.5377 | 0.0000 | |
| GSE53624 | ZNF469 | 84627 | 48122 | 3.0185 | 0.0000 | |
| GSE63941 | ZNF469 | 84627 | 230440_at | -1.3993 | 0.0052 | |
| GSE77861 | ZNF469 | 84627 | 230440_at | 0.0751 | 0.6175 | |
| GSE97050 | ZNF469 | 84627 | A_32_P116556 | 1.3723 | 0.0705 | |
| SRP007169 | ZNF469 | 84627 | RNAseq | 4.2213 | 0.0000 | |
| SRP008496 | ZNF469 | 84627 | RNAseq | 5.5877 | 0.0000 | |
| SRP064894 | ZNF469 | 84627 | RNAseq | 3.0724 | 0.0000 | |
| SRP133303 | ZNF469 | 84627 | RNAseq | 3.2933 | 0.0000 | |
| SRP159526 | ZNF469 | 84627 | RNAseq | 3.1633 | 0.0000 | |
| SRP193095 | ZNF469 | 84627 | RNAseq | 3.5248 | 0.0000 | |
| SRP219564 | ZNF469 | 84627 | RNAseq | 3.2256 | 0.0000 | |
| TCGA | ZNF469 | 84627 | RNAseq | 0.7204 | 0.0000 |
Upregulated datasets: 9; Downregulated datasets: 1.
Survival by ZNF469 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF469:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF469 | 84627 | 4 | 3 | 23 | |
| GSE20123 | ZNF469 | 84627 | 4 | 3 | 23 | |
| GSE43470 | ZNF469 | 84627 | 1 | 13 | 29 | |
| GSE46452 | ZNF469 | 84627 | 38 | 1 | 20 | |
| GSE47630 | ZNF469 | 84627 | 11 | 9 | 20 | |
| GSE54993 | ZNF469 | 84627 | 3 | 4 | 63 | |
| GSE54994 | ZNF469 | 84627 | 9 | 11 | 33 | |
| GSE60625 | ZNF469 | 84627 | 4 | 0 | 7 | |
| GSE74703 | ZNF469 | 84627 | 1 | 9 | 26 | |
| GSE74704 | ZNF469 | 84627 | 3 | 2 | 15 | |
| TCGA | ZNF469 | 84627 | 28 | 15 | 53 |
Total number of gains: 106; Total number of losses: 70; Total Number of normals: 312.
Somatic mutations of ZNF469:
Generating mutation plots.
Highly correlated genes for ZNF469:
Showing top 20/1313 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF469 | ADAMTS12 | 0.80687 | 8 | 0 | 7 |
| ZNF469 | COL5A1 | 0.805255 | 8 | 0 | 8 |
| ZNF469 | XPR1 | 0.801714 | 6 | 0 | 6 |
| ZNF469 | COL5A2 | 0.800897 | 8 | 0 | 8 |
| ZNF469 | FAM89A | 0.800058 | 3 | 0 | 3 |
| ZNF469 | ALPK2 | 0.789671 | 4 | 0 | 4 |
| ZNF469 | EVA1B | 0.786965 | 3 | 0 | 3 |
| ZNF469 | LRRC8C | 0.783057 | 3 | 0 | 3 |
| ZNF469 | THY1 | 0.780987 | 9 | 0 | 9 |
| ZNF469 | ARPC1B | 0.771903 | 6 | 0 | 6 |
| ZNF469 | NCF2 | 0.766143 | 5 | 0 | 5 |
| ZNF469 | CCL11 | 0.765101 | 3 | 0 | 3 |
| ZNF469 | CNTNAP1 | 0.764659 | 3 | 0 | 3 |
| ZNF469 | COL1A1 | 0.764137 | 8 | 0 | 8 |
| ZNF469 | SPON2 | 0.762543 | 4 | 0 | 3 |
| ZNF469 | VCAN | 0.761225 | 8 | 0 | 8 |
| ZNF469 | FCER1G | 0.761128 | 3 | 0 | 3 |
| ZNF469 | C11orf24 | 0.759918 | 7 | 0 | 7 |
| ZNF469 | COL6A3 | 0.759758 | 8 | 0 | 7 |
| ZNF469 | PYCR2 | 0.758937 | 3 | 0 | 3 |
For details and further investigation, click here
