| Full name: protein phosphatase 1 regulatory subunit 18 | Alias Symbol: phostensin | ||
| Type: protein-coding gene | Cytoband: 6p21.33 | ||
| Entrez ID: 170954 | HGNC ID: HGNC:29413 | Ensembl Gene: ENSG00000146112 | OMIM ID: 610990 |
Expression of PPP1R18:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PPP1R18 | 170954 | 224927_at | 0.7199 | 0.0659 | |
| GSE26886 | PPP1R18 | 170954 | 224927_at | 0.1851 | 0.4655 | |
| GSE45670 | PPP1R18 | 170954 | 224927_at | 0.0433 | 0.9042 | |
| GSE53622 | PPP1R18 | 170954 | 12876 | 0.7720 | 0.0000 | |
| GSE53624 | PPP1R18 | 170954 | 12876 | 0.9402 | 0.0000 | |
| GSE63941 | PPP1R18 | 170954 | 224927_at | -1.3361 | 0.0233 | |
| GSE77861 | PPP1R18 | 170954 | 224927_at | 0.5681 | 0.0592 | |
| GSE97050 | PPP1R18 | 170954 | A_33_P3287584 | 0.1835 | 0.3790 | |
| SRP007169 | PPP1R18 | 170954 | RNAseq | 1.2349 | 0.0038 | |
| SRP008496 | PPP1R18 | 170954 | RNAseq | 1.3676 | 0.0000 | |
| SRP064894 | PPP1R18 | 170954 | RNAseq | 0.8720 | 0.0001 | |
| SRP133303 | PPP1R18 | 170954 | RNAseq | 0.6197 | 0.0047 | |
| SRP159526 | PPP1R18 | 170954 | RNAseq | 0.5368 | 0.1351 | |
| SRP193095 | PPP1R18 | 170954 | RNAseq | 1.3698 | 0.0000 | |
| SRP219564 | PPP1R18 | 170954 | RNAseq | 0.4277 | 0.3412 |
Upregulated datasets: 3; Downregulated datasets: 1.
Survival by PPP1R18 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of PPP1R18:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PPP1R18 | 170954 | 5 | 1 | 24 | |
| GSE20123 | PPP1R18 | 170954 | 5 | 1 | 24 | |
| GSE43470 | PPP1R18 | 170954 | 5 | 1 | 37 | |
| GSE46452 | PPP1R18 | 170954 | 1 | 10 | 48 | |
| GSE47630 | PPP1R18 | 170954 | 7 | 3 | 30 | |
| GSE54993 | PPP1R18 | 170954 | 2 | 1 | 67 | |
| GSE54994 | PPP1R18 | 170954 | 11 | 4 | 38 | |
| GSE60625 | PPP1R18 | 170954 | 0 | 1 | 10 | |
| GSE74703 | PPP1R18 | 170954 | 5 | 0 | 31 | |
| GSE74704 | PPP1R18 | 170954 | 2 | 0 | 18 | |
| TCGA | PPP1R18 | 170954 | 18 | 16 | 62 |
Total number of gains: 61; Total number of losses: 38; Total Number of normals: 389.
Somatic mutations of PPP1R18:
Generating mutation plots.
Highly correlated genes for PPP1R18:
Showing top 20/1113 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PPP1R18 | FCGR3A | 0.781658 | 3 | 0 | 3 |
| PPP1R18 | STK32B | 0.779521 | 3 | 0 | 3 |
| PPP1R18 | LRRC8C | 0.777735 | 3 | 0 | 3 |
| PPP1R18 | GNG11 | 0.763023 | 3 | 0 | 3 |
| PPP1R18 | NCOR2 | 0.750371 | 3 | 0 | 3 |
| PPP1R18 | ADAMTS15 | 0.747399 | 3 | 0 | 3 |
| PPP1R18 | CRTC2 | 0.74563 | 3 | 0 | 3 |
| PPP1R18 | APLNR | 0.741988 | 3 | 0 | 3 |
| PPP1R18 | CD99L2 | 0.737509 | 3 | 0 | 3 |
| PPP1R18 | LHFPL2 | 0.727832 | 8 | 0 | 7 |
| PPP1R18 | PLAUR | 0.716916 | 8 | 0 | 8 |
| PPP1R18 | NNMT | 0.71651 | 3 | 0 | 3 |
| PPP1R18 | CNTNAP1 | 0.712707 | 3 | 0 | 3 |
| PPP1R18 | TNFRSF1A | 0.708523 | 3 | 0 | 3 |
| PPP1R18 | MMP11 | 0.704791 | 3 | 0 | 3 |
| PPP1R18 | NONO | 0.703853 | 5 | 0 | 5 |
| PPP1R18 | ZNF469 | 0.703052 | 5 | 0 | 5 |
| PPP1R18 | CACNA1B | 0.702773 | 3 | 0 | 3 |
| PPP1R18 | TMC8 | 0.69709 | 3 | 0 | 3 |
| PPP1R18 | AQP9 | 0.696884 | 4 | 0 | 4 |
For details and further investigation, click here
