| Full name: cytochrome c oxidase assembly factor 5 | Alias Symbol: MGC52110|FLJ27524|Pet191 | ||
| Type: protein-coding gene | Cytoband: 2q11.2 | ||
| Entrez ID: 493753 | HGNC ID: HGNC:33848 | Ensembl Gene: ENSG00000183513 | OMIM ID: 613920 |
Screen Evidence:
| |||
Expression of COA5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | COA5 | 493753 | 225410_at | 0.0480 | 0.8618 | |
| GSE26886 | COA5 | 493753 | 225409_at | 0.4999 | 0.0556 | |
| GSE45670 | COA5 | 493753 | 225410_at | 0.1401 | 0.4419 | |
| GSE53622 | COA5 | 493753 | 120036 | -0.0123 | 0.8769 | |
| GSE53624 | COA5 | 493753 | 120036 | 0.1596 | 0.0108 | |
| GSE63941 | COA5 | 493753 | 225410_at | 0.5771 | 0.1225 | |
| GSE77861 | COA5 | 493753 | 225410_at | 0.2945 | 0.0425 | |
| GSE97050 | COA5 | 493753 | A_23_P39910 | -0.3069 | 0.3582 | |
| SRP007169 | COA5 | 493753 | RNAseq | 0.2918 | 0.4392 | |
| SRP008496 | COA5 | 493753 | RNAseq | 0.8887 | 0.0030 | |
| SRP064894 | COA5 | 493753 | RNAseq | -0.0183 | 0.9058 | |
| SRP133303 | COA5 | 493753 | RNAseq | -0.0721 | 0.6546 | |
| SRP159526 | COA5 | 493753 | RNAseq | 0.9488 | 0.0632 | |
| SRP193095 | COA5 | 493753 | RNAseq | -0.1762 | 0.1605 | |
| SRP219564 | COA5 | 493753 | RNAseq | -0.4760 | 0.1857 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by COA5 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of COA5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | COA5 | 493753 | 6 | 2 | 22 | |
| GSE20123 | COA5 | 493753 | 6 | 2 | 22 | |
| GSE43470 | COA5 | 493753 | 3 | 2 | 38 | |
| GSE46452 | COA5 | 493753 | 2 | 3 | 54 | |
| GSE47630 | COA5 | 493753 | 7 | 0 | 33 | |
| GSE54993 | COA5 | 493753 | 0 | 6 | 64 | |
| GSE54994 | COA5 | 493753 | 10 | 0 | 43 | |
| GSE60625 | COA5 | 493753 | 0 | 3 | 8 | |
| GSE74703 | COA5 | 493753 | 3 | 2 | 31 | |
| GSE74704 | COA5 | 493753 | 4 | 1 | 15 | |
| TCGA | COA5 | 493753 | 33 | 5 | 58 |
Total number of gains: 74; Total number of losses: 26; Total Number of normals: 388.
Somatic mutations of COA5:
Generating mutation plots.
Highly correlated genes for COA5:
Showing top 20/509 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| COA5 | ATXN1L | 0.820728 | 3 | 0 | 3 |
| COA5 | BMPR1A | 0.784891 | 3 | 0 | 3 |
| COA5 | CKB | 0.764405 | 3 | 0 | 3 |
| COA5 | DHX40 | 0.757472 | 3 | 0 | 3 |
| COA5 | CEP290 | 0.751895 | 3 | 0 | 3 |
| COA5 | ZXDB | 0.745179 | 4 | 0 | 3 |
| COA5 | CYB5D1 | 0.736961 | 3 | 0 | 3 |
| COA5 | GZF1 | 0.735318 | 3 | 0 | 3 |
| COA5 | ISCA1 | 0.732188 | 3 | 0 | 3 |
| COA5 | FAR2 | 0.732099 | 3 | 0 | 3 |
| COA5 | PSMC3 | 0.730793 | 3 | 0 | 3 |
| COA5 | SFT2D3 | 0.728078 | 4 | 0 | 4 |
| COA5 | KIAA1257 | 0.726906 | 3 | 0 | 3 |
| COA5 | DZIP3 | 0.724227 | 4 | 0 | 3 |
| COA5 | KHNYN | 0.720829 | 3 | 0 | 3 |
| COA5 | SRI | 0.720453 | 3 | 0 | 3 |
| COA5 | BBX | 0.718814 | 3 | 0 | 3 |
| COA5 | EFCAB7 | 0.716451 | 4 | 0 | 3 |
| COA5 | SCAI | 0.713779 | 4 | 0 | 3 |
| COA5 | TSNARE1 | 0.713626 | 3 | 0 | 3 |
For details and further investigation, click here
