| Full name: LIM domain only 4 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1p22.3 | ||
| Entrez ID: 8543 | HGNC ID: HGNC:6644 | Ensembl Gene: ENSG00000143013 | OMIM ID: 603129 |
| Drug and gene relationship at DGIdb | |||
Expression of LMO4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LMO4 | 8543 | 209205_s_at | -0.2151 | 0.7837 | |
| GSE20347 | LMO4 | 8543 | 209205_s_at | -0.2836 | 0.2856 | |
| GSE23400 | LMO4 | 8543 | 209205_s_at | -0.3549 | 0.0063 | |
| GSE26886 | LMO4 | 8543 | 209205_s_at | -0.5569 | 0.0150 | |
| GSE29001 | LMO4 | 8543 | 209205_s_at | -0.4506 | 0.2230 | |
| GSE38129 | LMO4 | 8543 | 209205_s_at | -0.3957 | 0.0515 | |
| GSE45670 | LMO4 | 8543 | 209205_s_at | -0.4167 | 0.0889 | |
| GSE53622 | LMO4 | 8543 | 93956 | -0.4104 | 0.0022 | |
| GSE53624 | LMO4 | 8543 | 93956 | -0.5745 | 0.0000 | |
| GSE63941 | LMO4 | 8543 | 209205_s_at | -0.5064 | 0.4669 | |
| GSE77861 | LMO4 | 8543 | 209205_s_at | -0.7369 | 0.2125 | |
| GSE97050 | LMO4 | 8543 | A_33_P3298425 | -0.8125 | 0.0684 | |
| SRP007169 | LMO4 | 8543 | RNAseq | -1.1411 | 0.0036 | |
| SRP008496 | LMO4 | 8543 | RNAseq | -1.0791 | 0.0000 | |
| SRP064894 | LMO4 | 8543 | RNAseq | -0.3849 | 0.0326 | |
| SRP133303 | LMO4 | 8543 | RNAseq | -0.1882 | 0.4582 | |
| SRP159526 | LMO4 | 8543 | RNAseq | 0.2166 | 0.5712 | |
| SRP193095 | LMO4 | 8543 | RNAseq | -0.6840 | 0.0005 | |
| SRP219564 | LMO4 | 8543 | RNAseq | -0.4932 | 0.1656 | |
| TCGA | LMO4 | 8543 | RNAseq | -0.2094 | 0.0047 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by LMO4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LMO4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LMO4 | 8543 | 0 | 8 | 22 | |
| GSE20123 | LMO4 | 8543 | 0 | 8 | 22 | |
| GSE43470 | LMO4 | 8543 | 2 | 2 | 39 | |
| GSE46452 | LMO4 | 8543 | 1 | 1 | 57 | |
| GSE47630 | LMO4 | 8543 | 8 | 5 | 27 | |
| GSE54993 | LMO4 | 8543 | 0 | 1 | 69 | |
| GSE54994 | LMO4 | 8543 | 6 | 2 | 45 | |
| GSE60625 | LMO4 | 8543 | 0 | 0 | 11 | |
| GSE74703 | LMO4 | 8543 | 1 | 2 | 33 | |
| GSE74704 | LMO4 | 8543 | 0 | 5 | 15 | |
| TCGA | LMO4 | 8543 | 6 | 23 | 67 |
Total number of gains: 24; Total number of losses: 57; Total Number of normals: 407.
Somatic mutations of LMO4:
Generating mutation plots.
Highly correlated genes for LMO4:
Showing top 20/397 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LMO4 | AP3M1 | 0.842035 | 3 | 0 | 3 |
| LMO4 | VPS39 | 0.775027 | 3 | 0 | 3 |
| LMO4 | ADHFE1 | 0.769369 | 3 | 0 | 3 |
| LMO4 | COBLL1 | 0.762762 | 3 | 0 | 3 |
| LMO4 | ZACN | 0.730651 | 3 | 0 | 3 |
| LMO4 | GHITM | 0.713055 | 3 | 0 | 3 |
| LMO4 | SLC12A6 | 0.708788 | 4 | 0 | 3 |
| LMO4 | ABHD14B | 0.703999 | 4 | 0 | 3 |
| LMO4 | C5orf51 | 0.701792 | 3 | 0 | 3 |
| LMO4 | GPIHBP1 | 0.700664 | 3 | 0 | 3 |
| LMO4 | ZNF784 | 0.697834 | 4 | 0 | 4 |
| LMO4 | PSENEN | 0.693568 | 3 | 0 | 3 |
| LMO4 | ZBTB22 | 0.683828 | 3 | 0 | 3 |
| LMO4 | ANKRD6 | 0.682649 | 3 | 0 | 3 |
| LMO4 | RTN3 | 0.680656 | 3 | 0 | 3 |
| LMO4 | GLB1L2 | 0.677277 | 3 | 0 | 3 |
| LMO4 | KLF3 | 0.671021 | 5 | 0 | 4 |
| LMO4 | CCL28 | 0.668626 | 3 | 0 | 3 |
| LMO4 | SETX | 0.667199 | 4 | 0 | 3 |
| LMO4 | DNAJB9 | 0.666277 | 3 | 0 | 3 |
For details and further investigation, click here
