| Full name: eukaryotic translation initiation factor 3 subunit J | Alias Symbol: eIF3-p35|eIF3-alpha|eIF3j | ||
| Type: protein-coding gene | Cytoband: 15q21.1 | ||
| Entrez ID: 8669 | HGNC ID: HGNC:3270 | Ensembl Gene: ENSG00000104131 | OMIM ID: 603910 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of EIF3J:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EIF3J | 8669 | 208985_s_at | -0.1688 | 0.6641 | |
| GSE20347 | EIF3J | 8669 | 208985_s_at | -0.0699 | 0.7071 | |
| GSE23400 | EIF3J | 8669 | 208985_s_at | 0.1549 | 0.0498 | |
| GSE26886 | EIF3J | 8669 | 208985_s_at | 0.1061 | 0.6365 | |
| GSE29001 | EIF3J | 8669 | 208985_s_at | -0.3700 | 0.3805 | |
| GSE38129 | EIF3J | 8669 | 208985_s_at | 0.1152 | 0.4460 | |
| GSE45670 | EIF3J | 8669 | 208985_s_at | 0.1457 | 0.3356 | |
| GSE53622 | EIF3J | 8669 | 171724 | 0.0988 | 0.0827 | |
| GSE53624 | EIF3J | 8669 | 171724 | -0.0027 | 0.9650 | |
| GSE63941 | EIF3J | 8669 | 208985_s_at | 0.4631 | 0.3509 | |
| GSE77861 | EIF3J | 8669 | 208985_s_at | 0.2112 | 0.3377 | |
| GSE97050 | EIF3J | A_21_P0012407 | -0.3472 | 0.2264 | ||
| SRP007169 | EIF3J | 8669 | RNAseq | -0.1356 | 0.7081 | |
| SRP008496 | EIF3J | 8669 | RNAseq | 0.1260 | 0.6659 | |
| SRP064894 | EIF3J | 8669 | RNAseq | -0.4861 | 0.0000 | |
| SRP133303 | EIF3J | 8669 | RNAseq | 0.1286 | 0.4838 | |
| SRP159526 | EIF3J | 8669 | RNAseq | -0.1093 | 0.7884 | |
| SRP193095 | EIF3J | 8669 | RNAseq | -0.2042 | 0.0622 | |
| SRP219564 | EIF3J | 8669 | RNAseq | -0.4889 | 0.0550 | |
| TCGA | EIF3J | 8669 | RNAseq | 0.0125 | 0.7876 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by EIF3J expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EIF3J:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EIF3J | 8669 | 3 | 4 | 23 | |
| GSE20123 | EIF3J | 8669 | 3 | 5 | 22 | |
| GSE43470 | EIF3J | 8669 | 4 | 4 | 35 | |
| GSE46452 | EIF3J | 8669 | 3 | 7 | 49 | |
| GSE47630 | EIF3J | 8669 | 8 | 10 | 22 | |
| GSE54993 | EIF3J | 8669 | 4 | 6 | 60 | |
| GSE54994 | EIF3J | 8669 | 5 | 7 | 41 | |
| GSE60625 | EIF3J | 8669 | 4 | 0 | 7 | |
| GSE74703 | EIF3J | 8669 | 4 | 3 | 29 | |
| GSE74704 | EIF3J | 8669 | 1 | 2 | 17 | |
| TCGA | EIF3J | 8669 | 12 | 17 | 67 |
Total number of gains: 51; Total number of losses: 65; Total Number of normals: 372.
Somatic mutations of EIF3J:
Generating mutation plots.
Highly correlated genes for EIF3J:
Showing top 20/489 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EIF3J | COBLL1 | 0.760828 | 3 | 0 | 3 |
| EIF3J | SMAD2 | 0.735957 | 3 | 0 | 3 |
| EIF3J | MSH3 | 0.719727 | 3 | 0 | 3 |
| EIF3J | ENTPD3 | 0.719648 | 3 | 0 | 3 |
| EIF3J | INHBE | 0.712974 | 3 | 0 | 3 |
| EIF3J | MRPL50 | 0.705019 | 3 | 0 | 3 |
| EIF3J | RBKS | 0.697494 | 3 | 0 | 3 |
| EIF3J | MRPS22 | 0.697005 | 3 | 0 | 3 |
| EIF3J | DNAJA2 | 0.694935 | 5 | 0 | 4 |
| EIF3J | C15orf61 | 0.694559 | 4 | 0 | 3 |
| EIF3J | WDR61 | 0.691639 | 8 | 0 | 8 |
| EIF3J | RNASEH2C | 0.683731 | 3 | 0 | 3 |
| EIF3J | PHTF2 | 0.671461 | 3 | 0 | 3 |
| EIF3J | ANKMY2 | 0.670992 | 4 | 0 | 3 |
| EIF3J | ATL2 | 0.669807 | 4 | 0 | 3 |
| EIF3J | TMEM41B | 0.669427 | 4 | 0 | 3 |
| EIF3J | UBE2M | 0.666799 | 4 | 0 | 4 |
| EIF3J | COPS2 | 0.664554 | 13 | 0 | 12 |
| EIF3J | CNOT1 | 0.659591 | 3 | 0 | 3 |
| EIF3J | PLEKHG1 | 0.656596 | 3 | 0 | 3 |
For details and further investigation, click here
