| Full name: collagen type XXVII alpha 1 chain | Alias Symbol: KIAA1870|MGC11337|FLJ11895 | ||
| Type: protein-coding gene | Cytoband: 9q32 | ||
| Entrez ID: 85301 | HGNC ID: HGNC:22986 | Ensembl Gene: ENSG00000196739 | OMIM ID: 608461 |
| Drug and gene relationship at DGIdb | |||
Expression of COL27A1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | COL27A1 | 85301 | 225293_at | 1.4141 | 0.0140 | |
| GSE26886 | COL27A1 | 85301 | 225293_at | 1.7242 | 0.0019 | |
| GSE45670 | COL27A1 | 85301 | 225293_at | 1.5329 | 0.0001 | |
| GSE53622 | COL27A1 | 85301 | 166432 | 1.9511 | 0.0000 | |
| GSE53624 | COL27A1 | 85301 | 119796 | 1.6049 | 0.0000 | |
| GSE63941 | COL27A1 | 85301 | 225293_at | -0.0782 | 0.9315 | |
| GSE77861 | COL27A1 | 85301 | 225293_at | 0.8268 | 0.1204 | |
| GSE97050 | COL27A1 | 85301 | A_24_P363896 | 0.3039 | 0.2198 | |
| SRP007169 | COL27A1 | 85301 | RNAseq | 2.1818 | 0.0002 | |
| SRP008496 | COL27A1 | 85301 | RNAseq | 2.6119 | 0.0000 | |
| SRP064894 | COL27A1 | 85301 | RNAseq | 2.5529 | 0.0000 | |
| SRP133303 | COL27A1 | 85301 | RNAseq | 1.6985 | 0.0000 | |
| SRP193095 | COL27A1 | 85301 | RNAseq | 1.8210 | 0.0000 | |
| SRP219564 | COL27A1 | 85301 | RNAseq | 1.4082 | 0.0005 | |
| TCGA | COL27A1 | 85301 | RNAseq | 0.5743 | 0.0000 |
Upregulated datasets: 11; Downregulated datasets: 0.
Survival by COL27A1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of COL27A1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | COL27A1 | 85301 | 3 | 10 | 17 | |
| GSE20123 | COL27A1 | 85301 | 3 | 11 | 16 | |
| GSE43470 | COL27A1 | 85301 | 5 | 3 | 35 | |
| GSE46452 | COL27A1 | 85301 | 6 | 13 | 40 | |
| GSE47630 | COL27A1 | 85301 | 3 | 16 | 21 | |
| GSE54993 | COL27A1 | 85301 | 3 | 3 | 64 | |
| GSE54994 | COL27A1 | 85301 | 9 | 10 | 34 | |
| GSE60625 | COL27A1 | 85301 | 0 | 0 | 11 | |
| GSE74703 | COL27A1 | 85301 | 4 | 3 | 29 | |
| GSE74704 | COL27A1 | 85301 | 2 | 7 | 11 | |
| TCGA | COL27A1 | 85301 | 27 | 21 | 48 |
Total number of gains: 65; Total number of losses: 97; Total Number of normals: 326.
Somatic mutations of COL27A1:
Generating mutation plots.
Highly correlated genes for COL27A1:
Showing top 20/719 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| COL27A1 | NID2 | 0.797294 | 3 | 0 | 3 |
| COL27A1 | SPATA2L | 0.793725 | 3 | 0 | 3 |
| COL27A1 | LRFN4 | 0.788345 | 4 | 0 | 4 |
| COL27A1 | DNMT3B | 0.774589 | 7 | 0 | 7 |
| COL27A1 | PMEPA1 | 0.770881 | 7 | 0 | 7 |
| COL27A1 | MIIP | 0.770419 | 3 | 0 | 3 |
| COL27A1 | PTK7 | 0.761089 | 6 | 0 | 6 |
| COL27A1 | HOXD11 | 0.75631 | 6 | 0 | 6 |
| COL27A1 | DBF4B | 0.737931 | 4 | 0 | 4 |
| COL27A1 | SALL4 | 0.736133 | 7 | 0 | 7 |
| COL27A1 | RFX8 | 0.735924 | 3 | 0 | 3 |
| COL27A1 | LAMC2 | 0.729414 | 7 | 0 | 6 |
| COL27A1 | KIF26B | 0.728511 | 6 | 0 | 5 |
| COL27A1 | VAV2 | 0.726612 | 8 | 0 | 7 |
| COL27A1 | BGN | 0.725006 | 6 | 0 | 5 |
| COL27A1 | LOXL2 | 0.724944 | 6 | 0 | 6 |
| COL27A1 | NPM2 | 0.724871 | 4 | 0 | 4 |
| COL27A1 | FUT1 | 0.7234 | 3 | 0 | 3 |
| COL27A1 | FOXD2-AS1 | 0.722591 | 3 | 0 | 3 |
| COL27A1 | CHST13 | 0.722222 | 3 | 0 | 3 |
For details and further investigation, click here
