| Full name: collagen type IX alpha 1 chain | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 6q13 | ||
| Entrez ID: 1297 | HGNC ID: HGNC:2217 | Ensembl Gene: ENSG00000112280 | OMIM ID: 120210 |
| Drug and gene relationship at DGIdb | |||
COL9A1 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04151 | PI3K-Akt signaling pathway | |
| hsa04510 | Focal adhesion |
Expression of COL9A1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | COL9A1 | 1297 | 222008_at | 0.0952 | 0.8270 | |
| GSE20347 | COL9A1 | 1297 | 222008_at | 0.0891 | 0.4203 | |
| GSE23400 | COL9A1 | 1297 | 222008_at | -0.0280 | 0.3542 | |
| GSE26886 | COL9A1 | 1297 | 222008_at | 0.5163 | 0.0081 | |
| GSE29001 | COL9A1 | 1297 | 222008_at | 0.0185 | 0.9090 | |
| GSE38129 | COL9A1 | 1297 | 222008_at | -0.0504 | 0.6715 | |
| GSE45670 | COL9A1 | 1297 | 222008_at | -0.1711 | 0.0425 | |
| GSE53622 | COL9A1 | 1297 | 49995 | 0.0700 | 0.6701 | |
| GSE53624 | COL9A1 | 1297 | 49995 | 0.0766 | 0.4053 | |
| GSE63941 | COL9A1 | 1297 | 222008_at | 0.2942 | 0.0371 | |
| GSE77861 | COL9A1 | 1297 | 222008_at | -0.0525 | 0.7590 | |
| GSE97050 | COL9A1 | 1297 | A_24_P311856 | -0.0147 | 0.9644 | |
| TCGA | COL9A1 | 1297 | RNAseq | -1.2944 | 0.0839 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by COL9A1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of COL9A1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | COL9A1 | 1297 | 2 | 2 | 26 | |
| GSE20123 | COL9A1 | 1297 | 2 | 1 | 27 | |
| GSE43470 | COL9A1 | 1297 | 3 | 0 | 40 | |
| GSE46452 | COL9A1 | 1297 | 2 | 11 | 46 | |
| GSE47630 | COL9A1 | 1297 | 8 | 4 | 28 | |
| GSE54993 | COL9A1 | 1297 | 3 | 2 | 65 | |
| GSE54994 | COL9A1 | 1297 | 10 | 4 | 39 | |
| GSE60625 | COL9A1 | 1297 | 0 | 2 | 9 | |
| GSE74703 | COL9A1 | 1297 | 3 | 0 | 33 | |
| GSE74704 | COL9A1 | 1297 | 0 | 1 | 19 | |
| TCGA | COL9A1 | 1297 | 12 | 18 | 66 |
Total number of gains: 45; Total number of losses: 45; Total Number of normals: 398.
Somatic mutations of COL9A1:
Generating mutation plots.
Highly correlated genes for COL9A1:
Showing top 20/82 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| COL9A1 | LRP5L | 0.65029 | 4 | 0 | 3 |
| COL9A1 | BCAT2 | 0.634752 | 3 | 0 | 3 |
| COL9A1 | THUMPD2 | 0.614899 | 3 | 0 | 3 |
| COL9A1 | FBXO31 | 0.613936 | 4 | 0 | 3 |
| COL9A1 | TLCD1 | 0.609834 | 3 | 0 | 3 |
| COL9A1 | KIAA1324 | 0.608632 | 3 | 0 | 3 |
| COL9A1 | ARHGEF19 | 0.607186 | 3 | 0 | 3 |
| COL9A1 | PAK3 | 0.602874 | 5 | 0 | 3 |
| COL9A1 | STMN4 | 0.601665 | 4 | 0 | 4 |
| COL9A1 | NUDT17 | 0.596742 | 3 | 0 | 3 |
| COL9A1 | FGF3 | 0.592282 | 4 | 0 | 3 |
| COL9A1 | TUBB2B | 0.591279 | 3 | 0 | 3 |
| COL9A1 | CITED1 | 0.586842 | 4 | 0 | 4 |
| COL9A1 | HPN | 0.582193 | 4 | 0 | 3 |
| COL9A1 | SOX10 | 0.575571 | 5 | 0 | 3 |
| COL9A1 | PCDH8 | 0.571998 | 5 | 0 | 4 |
| COL9A1 | PLD3 | 0.571086 | 3 | 0 | 3 |
| COL9A1 | HEATR1 | 0.569679 | 3 | 0 | 3 |
| COL9A1 | DBN1 | 0.56953 | 4 | 0 | 3 |
| COL9A1 | HDAC2 | 0.568804 | 3 | 0 | 3 |
For details and further investigation, click here
