TLCD1

 

Full name: TLC domain containing 1 Alias Symbol: 
Type: protein-coding gene Cytoband: 17q11.2
Entrez ID: 116238 HGNC ID: HGNC:25177 Ensembl Gene: ENSG00000160606 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of TLCD1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TLCD1 116238 227804_at 0.8177 0.0865
GSE26886 TLCD1 116238 227804_at 0.1540 0.6901
GSE45670 TLCD1 116238 227804_at 0.5197 0.1138
GSE53622 TLCD1 116238 93093 0.5444 0.0003
GSE53624 TLCD1 116238 93093 0.3696 0.0000
GSE63941 TLCD1 116238 227804_at 1.6297 0.0290
GSE77861 TLCD1 116238 227804_at 0.8421 0.0768
GSE97050 TLCD1 116238 A_23_P420417 0.6783 0.1476
SRP007169 TLCD1 116238 RNAseq 0.2258 0.6824
SRP064894 TLCD1 116238 RNAseq 0.3064 0.2941
SRP133303 TLCD1 116238 RNAseq 0.2120 0.3060
SRP159526 TLCD1 116238 RNAseq 0.0480 0.8800
SRP193095 TLCD1 116238 RNAseq 0.0166 0.9199
SRP219564 TLCD1 116238 RNAseq 0.1424 0.8353
TCGA TLCD1 116238 RNAseq 0.5058 0.0001

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by TLCD1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of TLCD1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TLCD1 116238 9 1 20
GSE20123 TLCD1 116238 9 1 20
GSE43470 TLCD1 116238 0 1 42
GSE46452 TLCD1 116238 33 1 25
GSE47630 TLCD1 116238 7 1 32
GSE54993 TLCD1 116238 2 3 65
GSE54994 TLCD1 116238 7 6 40
GSE60625 TLCD1 116238 4 0 7
GSE74703 TLCD1 116238 0 1 35
GSE74704 TLCD1 116238 7 1 12
TCGA TLCD1 116238 21 10 65

Total number of gains: 99; Total number of losses: 26; Total Number of normals: 363.  

 

Somatic mutations of TLCD1:

 

Generating mutation plots.

 

Highly correlated genes for TLCD1:

 

Showing top 20/736 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TLCD1SYT70.789542303
TLCD1DHRS130.772055505
TLCD1INO80B0.770851303
TLCD1SQLE0.766102303
TLCD1SPINT20.717947404
TLCD1TM9SF40.716747403
TLCD1TMEM2230.704021404
TLCD1MGST10.7037303
TLCD1PPP1R9B0.70044303
TLCD1OSBPL30.699156303
TLCD1RNF1490.690784303
TLCD1MSTO10.688674303
TLCD1CSTF30.687806303
TLCD1CCDC860.682899404
TLCD1SLC1A50.682741404
TLCD1KPNA20.682088504
TLCD1SPAG50.681732706
TLCD1HELLS0.681164504
TLCD1MYO190.679141606
TLCD1FBXO410.679039403

For details and further investigation, click here