| Full name: RB binding protein 4, chromatin remodeling factor | Alias Symbol: RbAp48|NURF55|lin-53 | ||
| Type: protein-coding gene | Cytoband: 1p35.1 | ||
| Entrez ID: 5928 | HGNC ID: HGNC:9887 | Ensembl Gene: ENSG00000162521 | OMIM ID: 602923 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of RBBP4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RBBP4 | 5928 | 210371_s_at | 0.3899 | 0.2147 | |
| GSE20347 | RBBP4 | 5928 | 210371_s_at | 0.5738 | 0.0057 | |
| GSE23400 | RBBP4 | 5928 | 217301_x_at | 0.5321 | 0.0000 | |
| GSE26886 | RBBP4 | 5928 | 210371_s_at | -1.1814 | 0.0000 | |
| GSE29001 | RBBP4 | 5928 | 210371_s_at | 0.6389 | 0.1196 | |
| GSE38129 | RBBP4 | 5928 | 210371_s_at | 0.5482 | 0.0005 | |
| GSE45670 | RBBP4 | 5928 | 210371_s_at | 0.1585 | 0.3095 | |
| GSE53622 | RBBP4 | 5928 | 42715 | 0.4506 | 0.0000 | |
| GSE53624 | RBBP4 | 5928 | 42715 | 0.4789 | 0.0000 | |
| GSE63941 | RBBP4 | 5928 | 210371_s_at | 0.5056 | 0.2533 | |
| GSE77861 | RBBP4 | 5928 | 210371_s_at | 0.1283 | 0.7477 | |
| GSE97050 | RBBP4 | 5928 | A_23_P326691 | -0.0525 | 0.8895 | |
| SRP007169 | RBBP4 | 5928 | RNAseq | 0.7563 | 0.0425 | |
| SRP008496 | RBBP4 | 5928 | RNAseq | 0.8140 | 0.0000 | |
| SRP064894 | RBBP4 | 5928 | RNAseq | 0.4584 | 0.0195 | |
| SRP133303 | RBBP4 | 5928 | RNAseq | 0.3562 | 0.0086 | |
| SRP159526 | RBBP4 | 5928 | RNAseq | 0.5606 | 0.0571 | |
| SRP193095 | RBBP4 | 5928 | RNAseq | 0.1410 | 0.0679 | |
| SRP219564 | RBBP4 | 5928 | RNAseq | 0.0042 | 0.9814 | |
| TCGA | RBBP4 | 5928 | RNAseq | 0.0280 | 0.5302 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by RBBP4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RBBP4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RBBP4 | 5928 | 2 | 5 | 23 | |
| GSE20123 | RBBP4 | 5928 | 2 | 4 | 24 | |
| GSE43470 | RBBP4 | 5928 | 5 | 6 | 32 | |
| GSE46452 | RBBP4 | 5928 | 5 | 1 | 53 | |
| GSE47630 | RBBP4 | 5928 | 8 | 3 | 29 | |
| GSE54993 | RBBP4 | 5928 | 1 | 1 | 68 | |
| GSE54994 | RBBP4 | 5928 | 11 | 2 | 40 | |
| GSE60625 | RBBP4 | 5928 | 0 | 0 | 11 | |
| GSE74703 | RBBP4 | 5928 | 4 | 3 | 29 | |
| GSE74704 | RBBP4 | 5928 | 1 | 0 | 19 | |
| TCGA | RBBP4 | 5928 | 12 | 19 | 65 |
Total number of gains: 51; Total number of losses: 44; Total Number of normals: 393.
Somatic mutations of RBBP4:
Generating mutation plots.
Highly correlated genes for RBBP4:
Showing top 20/559 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RBBP4 | PDIK1L | 0.728981 | 3 | 0 | 3 |
| RBBP4 | DPP8 | 0.728001 | 3 | 0 | 3 |
| RBBP4 | KLHL36 | 0.726265 | 3 | 0 | 3 |
| RBBP4 | ATP6V1H | 0.726067 | 3 | 0 | 3 |
| RBBP4 | RPAP1 | 0.715966 | 3 | 0 | 3 |
| RBBP4 | CEP170 | 0.70869 | 3 | 0 | 3 |
| RBBP4 | GLOD4 | 0.706893 | 6 | 0 | 5 |
| RBBP4 | CASP8AP2 | 0.706425 | 9 | 0 | 9 |
| RBBP4 | PAPSS1 | 0.704197 | 3 | 0 | 3 |
| RBBP4 | RSPRY1 | 0.699117 | 3 | 0 | 3 |
| RBBP4 | HNRNPR | 0.698144 | 8 | 0 | 8 |
| RBBP4 | NDUFA10 | 0.693228 | 4 | 0 | 3 |
| RBBP4 | GNG10 | 0.68936 | 3 | 0 | 3 |
| RBBP4 | POLDIP3 | 0.688902 | 5 | 0 | 5 |
| RBBP4 | SSH2 | 0.687513 | 3 | 0 | 3 |
| RBBP4 | PDHA1 | 0.686609 | 3 | 0 | 3 |
| RBBP4 | ARF3 | 0.685919 | 3 | 0 | 3 |
| RBBP4 | PPP1R8 | 0.681582 | 7 | 0 | 6 |
| RBBP4 | CLPTM1L | 0.680059 | 3 | 0 | 3 |
| RBBP4 | MRFAP1L1 | 0.674258 | 5 | 0 | 5 |
For details and further investigation, click here
