| Full name: carboxypeptidase X, M14 family member 2 | Alias Symbol: UNQ676|CPX2 | ||
| Type: protein-coding gene | Cytoband: 10q26.13 | ||
| Entrez ID: 119587 | HGNC ID: HGNC:26977 | Ensembl Gene: ENSG00000121898 | OMIM ID: 617348 |
| Drug and gene relationship at DGIdb | |||
Expression of CPXM2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CPXM2 | 119587 | 226824_at | -1.2918 | 0.2893 | |
| GSE26886 | CPXM2 | 119587 | 226824_at | 0.0769 | 0.7531 | |
| GSE45670 | CPXM2 | 119587 | 226824_at | -1.3933 | 0.0001 | |
| GSE53622 | CPXM2 | 119587 | 109195 | -0.8844 | 0.0001 | |
| GSE53624 | CPXM2 | 119587 | 109195 | -0.8051 | 0.0000 | |
| GSE63941 | CPXM2 | 119587 | 1570026_at | 0.0742 | 0.6321 | |
| GSE77861 | CPXM2 | 119587 | 226824_at | 0.1458 | 0.4698 | |
| GSE97050 | CPXM2 | 119587 | A_33_P3333158 | -1.0849 | 0.1230 | |
| SRP007169 | CPXM2 | 119587 | RNAseq | 1.1493 | 0.0238 | |
| SRP008496 | CPXM2 | 119587 | RNAseq | 1.2331 | 0.0014 | |
| SRP064894 | CPXM2 | 119587 | RNAseq | 0.3380 | 0.4152 | |
| SRP133303 | CPXM2 | 119587 | RNAseq | 0.2043 | 0.7108 | |
| SRP159526 | CPXM2 | 119587 | RNAseq | 0.1056 | 0.8036 | |
| SRP193095 | CPXM2 | 119587 | RNAseq | 1.0449 | 0.0013 | |
| SRP219564 | CPXM2 | 119587 | RNAseq | -0.5152 | 0.6687 | |
| TCGA | CPXM2 | 119587 | RNAseq | -0.5193 | 0.0109 |
Upregulated datasets: 3; Downregulated datasets: 1.
Survival by CPXM2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CPXM2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CPXM2 | 119587 | 1 | 6 | 23 | |
| GSE20123 | CPXM2 | 119587 | 1 | 6 | 23 | |
| GSE43470 | CPXM2 | 119587 | 0 | 10 | 33 | |
| GSE46452 | CPXM2 | 119587 | 0 | 11 | 48 | |
| GSE47630 | CPXM2 | 119587 | 2 | 14 | 24 | |
| GSE54993 | CPXM2 | 119587 | 8 | 1 | 61 | |
| GSE54994 | CPXM2 | 119587 | 2 | 8 | 43 | |
| GSE60625 | CPXM2 | 119587 | 0 | 0 | 11 | |
| GSE74703 | CPXM2 | 119587 | 0 | 6 | 30 | |
| GSE74704 | CPXM2 | 119587 | 1 | 2 | 17 | |
| TCGA | CPXM2 | 119587 | 4 | 27 | 65 |
Total number of gains: 19; Total number of losses: 91; Total Number of normals: 378.
Somatic mutations of CPXM2:
Generating mutation plots.
Highly correlated genes for CPXM2:
Showing top 20/657 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CPXM2 | WWTR1 | 0.779157 | 4 | 0 | 4 |
| CPXM2 | CYSLTR1 | 0.773066 | 5 | 0 | 5 |
| CPXM2 | TLN1 | 0.762164 | 4 | 0 | 4 |
| CPXM2 | PALLD | 0.761872 | 4 | 0 | 4 |
| CPXM2 | ID4 | 0.761822 | 3 | 0 | 3 |
| CPXM2 | SPOP | 0.749491 | 4 | 0 | 4 |
| CPXM2 | PDE5A | 0.74656 | 6 | 0 | 5 |
| CPXM2 | SCN7A | 0.744679 | 5 | 0 | 5 |
| CPXM2 | CYP4V2 | 0.742478 | 3 | 0 | 3 |
| CPXM2 | COMMD6 | 0.73881 | 3 | 0 | 3 |
| CPXM2 | PODN | 0.738216 | 4 | 0 | 4 |
| CPXM2 | MRVI1 | 0.737428 | 7 | 0 | 6 |
| CPXM2 | LINC01279 | 0.736255 | 3 | 0 | 3 |
| CPXM2 | NEGR1 | 0.727361 | 5 | 0 | 5 |
| CPXM2 | PEG3 | 0.724062 | 3 | 0 | 3 |
| CPXM2 | GSN | 0.720877 | 4 | 0 | 4 |
| CPXM2 | MYL5 | 0.72013 | 3 | 0 | 3 |
| CPXM2 | CILP | 0.715459 | 5 | 0 | 5 |
| CPXM2 | HPSE2 | 0.715219 | 5 | 0 | 5 |
| CPXM2 | PPP1R14A | 0.713786 | 6 | 0 | 6 |
For details and further investigation, click here
