| Full name: COMM domain containing 8 | Alias Symbol: FLJ20502 | ||
| Type: protein-coding gene | Cytoband: 4p12 | ||
| Entrez ID: 54951 | HGNC ID: HGNC:26036 | Ensembl Gene: ENSG00000169019 | OMIM ID: 616656 |
| Drug and gene relationship at DGIdb | |||
Expression of COMMD8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | COMMD8 | 54951 | 218351_at | -0.4297 | 0.3993 | |
| GSE20347 | COMMD8 | 54951 | 218351_at | -0.8165 | 0.0000 | |
| GSE23400 | COMMD8 | 54951 | 218351_at | -0.1221 | 0.1175 | |
| GSE26886 | COMMD8 | 54951 | 218351_at | -1.2014 | 0.0001 | |
| GSE29001 | COMMD8 | 54951 | 218351_at | -0.2962 | 0.5454 | |
| GSE38129 | COMMD8 | 54951 | 218351_at | -0.4236 | 0.0063 | |
| GSE45670 | COMMD8 | 54951 | 218351_at | -0.1350 | 0.4287 | |
| GSE53622 | COMMD8 | 54951 | 33228 | -0.3096 | 0.0001 | |
| GSE53624 | COMMD8 | 54951 | 169744 | -0.5187 | 0.0000 | |
| GSE63941 | COMMD8 | 54951 | 218351_at | -0.2653 | 0.4971 | |
| GSE77861 | COMMD8 | 54951 | 218351_at | -0.9407 | 0.0032 | |
| GSE97050 | COMMD8 | 54951 | A_33_P3285077 | 0.1509 | 0.6594 | |
| SRP007169 | COMMD8 | 54951 | RNAseq | -0.8607 | 0.0684 | |
| SRP008496 | COMMD8 | 54951 | RNAseq | -0.7592 | 0.0085 | |
| SRP064894 | COMMD8 | 54951 | RNAseq | -0.2893 | 0.1318 | |
| SRP133303 | COMMD8 | 54951 | RNAseq | 0.1539 | 0.4976 | |
| SRP159526 | COMMD8 | 54951 | RNAseq | -0.7913 | 0.0092 | |
| SRP193095 | COMMD8 | 54951 | RNAseq | -1.1009 | 0.0000 | |
| SRP219564 | COMMD8 | 54951 | RNAseq | -0.7852 | 0.0539 | |
| TCGA | COMMD8 | 54951 | RNAseq | 0.1819 | 0.0066 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by COMMD8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of COMMD8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | COMMD8 | 54951 | 1 | 15 | 14 | |
| GSE20123 | COMMD8 | 54951 | 1 | 15 | 14 | |
| GSE43470 | COMMD8 | 54951 | 0 | 13 | 30 | |
| GSE46452 | COMMD8 | 54951 | 1 | 37 | 21 | |
| GSE47630 | COMMD8 | 54951 | 1 | 18 | 21 | |
| GSE54993 | COMMD8 | 54951 | 7 | 0 | 63 | |
| GSE54994 | COMMD8 | 54951 | 4 | 9 | 40 | |
| GSE60625 | COMMD8 | 54951 | 0 | 0 | 11 | |
| GSE74703 | COMMD8 | 54951 | 0 | 11 | 25 | |
| GSE74704 | COMMD8 | 54951 | 0 | 9 | 11 | |
| TCGA | COMMD8 | 54951 | 16 | 33 | 47 |
Total number of gains: 31; Total number of losses: 160; Total Number of normals: 297.
Somatic mutations of COMMD8:
Generating mutation plots.
Highly correlated genes for COMMD8:
Showing top 20/1423 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| COMMD8 | SLC12A6 | 0.784395 | 3 | 0 | 3 |
| COMMD8 | ALG13 | 0.770108 | 4 | 0 | 4 |
| COMMD8 | NANS | 0.751203 | 3 | 0 | 3 |
| COMMD8 | IPMK | 0.750623 | 4 | 0 | 4 |
| COMMD8 | KLHDC2 | 0.750354 | 3 | 0 | 3 |
| COMMD8 | ATG2B | 0.741699 | 3 | 0 | 3 |
| COMMD8 | DDX52 | 0.738699 | 3 | 0 | 3 |
| COMMD8 | FYTTD1 | 0.731891 | 3 | 0 | 3 |
| COMMD8 | RALGPS2 | 0.723184 | 5 | 0 | 4 |
| COMMD8 | FAHD1 | 0.722611 | 4 | 0 | 4 |
| COMMD8 | KIF21A | 0.718749 | 4 | 0 | 4 |
| COMMD8 | SH3PXD2A-AS1 | 0.716138 | 3 | 0 | 3 |
| COMMD8 | EMCN | 0.707407 | 3 | 0 | 3 |
| COMMD8 | SLC22A15 | 0.70538 | 5 | 0 | 4 |
| COMMD8 | SLC35A5 | 0.704126 | 4 | 0 | 3 |
| COMMD8 | GAPT | 0.703644 | 3 | 0 | 3 |
| COMMD8 | C2CD2 | 0.702133 | 3 | 0 | 3 |
| COMMD8 | ORMDL2 | 0.701277 | 7 | 0 | 6 |
| COMMD8 | FBXL3 | 0.70025 | 4 | 0 | 3 |
| COMMD8 | TMEM167A | 0.700112 | 4 | 0 | 3 |
For details and further investigation, click here
